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Clinical Research Support

Protocol Review and Monitoring System (PRMS)

Protocol Review and Monitoring System (PRMS)

The Protocol Review and Monitoring System (PRMS) at Dana-Farber/Harvard Cancer Center (DF/HCC) supports the design, review, activation, and performance of oncology protocols across its clinical sites.The Office for Human Research Studies (OHRS) manages the PRMS system, from submission of protocols by the disease programs through initial scientific review, IRB review, activation, and ongoing scientific review.

Scientific leadership for PRMS is provided by Bruce Chabner, MD (MGH) in his role as  DF/HCC Associate Director for Clinical Sciences. Dr. Chabner chairs the Clinical Sciences Coordinating Committee, which supervises the academic activities of the Disease Programs. Importantly, there is continuing review of the entire clinical research process and infrastructure by the DF/HCC Executive Committee to ensure optimal function of the process. This provides continuing oversight and evaluation so that any changes required to make the system more effective can be implemented in a timely manner.

Administrative leadership is provided by Drew Memmott, DFCI Senior Vice President for Research Administration, who also serves as Associate Director for Administration, DF/HCC.