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Core Facilities

Biostatistics

Description

Descriptions

The Biostatistics Core facility is a shared resource supporting consultation on biostatistics and epidemiology throughout the Dana-Farber/Harvard Cancer Center (DF/HCC). The mission of the core is to ensure that experimental designs, study monitoring and data analyses take advantage of robust, efficient methods that reflect 'best practices' in biostatistics and epidemiology; to support NIH-funded peer reviewed grants that do not contain salary support for statisticians; and to enable pilot and small scale studies to become part of successful applications for peer-reviewed funding. The specific objectives for this Biostatistics Core are to provide:

  1. Expertise for the planning, conduct, analysis and reporting of clinical trials, epidemiologic and population based studies, studies in genetic susceptibility of cancer, and experiments in basic research in the biology of cancer
     
  2. Advice and support in the preparation of grant applications of DFIHCC members.
     
  3. Scientific computing for data analysis and scientific graphics necessary for analyses of epidemiological, clinical, basic science, and genomic studies.
     
  4. Advice and consultation to the Quality Assurance Office for Clinical Trials (QACT) on efficient and accurate database design and management of clinical research data.
  5. Computer support for the clinical research database, using the lngres system on the Department of Biostatistics and Computational Biology (DFCI) network.
     
  6. Advice and consultation to the Office for the Protection of Research Risks (OPRS) in the scientific and human protection reviews of clinical trials through membership on the DF/HCC Scientific Review Committees and the DFCI IRB, which serves as the central IRB for the DF/HCC.
     
  7. Education for members of the DF/HCC in the areas of study design, data collection, computerization, and statistical methods for laboratory, clinical and population based studies.