DF/HCC Cancer Proteomics Center

 Functional genomic and proteomic technologies provide the means to define and compare protein profiles in normal and pathological samples, correlate protein profiles with biological activities, define disease mechanisms at a molecular level, establish interrelationships among proteins, identify temporal patterns of expression, and define the function of uncharacterized proteins. As a result, there is intense interest in applying proteomics to foster a better understanding of cancer processes, develop new biomarkers for diagnosis, early detection, prediction and prognosis of cancer, identify tumor antigens recognized by the immune system, discover new molecular targets for accelerated drug development and identify markers for therapeutic efficacy, toxicity and patient stratification leading ultimately to better management of cancer patients.

The mission of the DF/HCC Cancer Proteomics Core is to develop a comprehensive and interdisciplinary proteomics core for High Sensitivity, High Resolution and High Throughput Proteomics with particular emphasis on in depth proteomic consultation, referral to the optimal proteomics facility and a strong focus on clinical sample analysis. The core will combine consultation, service and education into a comprehensive, translationally and clinically oriented proteomics core.