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Core Facilities

Rodent Histopathology (Pathology)



Bassing CH, Suh H, Ferguson DO, Chua KF, Manis J, Eckersdorff M, Gleason M, Bronson R, Lee C, Alt FW. 2003. Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors. Cell. 114:359-70.

Biswas DK, Dai S-C, Weiser B, Graner E, and Pardee AB. 2001. The nuclear factor kappa B (NF-kB): A potential therapeutic target for estrogen receptor negative breast cancers. Proc. Natl. Acad. Sci, USA 98: 10386-10391.

Ciemerych MA, Kenney AM, Sicinska E, Kalaszczynska I, Bronson RT, Rowitch DH, Gardner H, Sicinski P. 2002. Development of mice expressing a single D-type cyclin. Genes Dev. 16:3277-89.

Deleault N, Dolph P, Cook M, Nishina K, Feany MB, Harris D. 2003. Supattapone S. Post-transcriptional Suppression of Pathogenic Prion Protein Expression in Drosophila Neurons. J Neurochem. 85:1614-23.

Fischer, F.R., L. Santambrogio, Y. Luo, M.A. Berman, W.W. Hancock, and M.E. Dorf. 2000. Modulation of experimental autoimmune encephalomyelitis: Effect of altered peptide ligand on chemokine and chemokine receptor expression. J Neuroimmunol. 110: 195-208.

Fruman DA, Mauvais-Jarvis F, Pollard DA, Yballe CM, Brazil D, Bronson RT, Kahn CR, Cantley LC. 2000. Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p8 alpha. Nature Genet. 26:379-82.

Geng Y, Yu Q, Sicinska E, Das M, Bronson RT, Sicinski P.2001. Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice. Proc Natl Acad Sci U S A. 98:194-9.

Gounari F, Signoretti S, Bronson R, Klein L, Sellers WR, Kum J, Siermann A, Taketo MM, von Boehmer H, Khazaie K. 2002. Stabilization of beta-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentitation of other secretory epithelia. Oncogene 21:4099-4107.

Hock H, Meade E, Medeiros S, Schindler JW, Valk PJ, Fujiwara Y, Orkin SH. 2004. Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival. Genes Dev. 18:2336-41.

Katz SG, Williams A, Yang J, Fujiwara Y, Tsang AP, Epstein JA, Orkin SH. 2003. Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development. Proc Natl Acad Sci U S A. 100:14030-5.

Kim YM, Asavaroengchai W, Bronson R, Sykes M. 2003. Graft-versus-host disease can be separated from graft-versus-lymphoma effects by control fo lymphocyte trafficking with FTY20. J Clin Invest 111:659-669

Kung AL, Rebel VI, Bronson RT, Ch’ng L-E, Sieff CA, Livingston DM, Yao T-P. 2000. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Develop. 14: 272-277.

Lam, Y.P., and Breakefield, X.O. 2001. Potential of gene therapy for brain tumors. Human Molecular Genetics, 10:777-787.

Lawler J, Miao WM, Duquette M, Bouck N, Bronson RT, Hynes RO. 2001. Thrombospondin -1 gene expression affects survival and tumor spectrum in p53-deficient mice. Am J Pathology, 159:1949-1956.

Li D, Dower K, Ma Y, Benjamin TL. 2001. A ‘Tumor Host Range’ Selection Procedure Identifies p150sal2 as a target of Polyoma Large T Antigen. PNAS 98:12619-14624.

Li S, Wang Q, Chakladar A, Bronson RT, Bernards A. 2000. Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1. Mol Cell Biol. 20:697-701.

McDannold N, Fossheim SL, Rasmussen H, Martin H, Vykhodtseva N, Hynynen K. 2004. In vivo evaluation of a temperature-activated paramagnetic liposomal MRI contrast agent: Initial results in rabbit liver and kidney. Radiology 230: 743-752.

Mitsiades CS, Mitsiades NS, Bronson RT, Chauhan D, Munshi N, Treon SP, Maxwell CA, Pilarski L, Hideshima T, Hoffman RM, Anderson KC. 2003. Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications. Cancer Res. 63:6689-96.

Roberts CW, Leroux MM, Fleming MD, Orkin SH. 2002. Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5. Cancer Cell. 2:415-25.

Santambrogio L, Pakaski M, Wong ML, Cipriani B, Brosnan CF, Lees MB, and Dorf ME. 1999. Antigen presenting capacity of brain microvasculature in altered peptide ligand modulation of experimental allergic encephalomyelitis. J Neuroimmunol; 93:81-91.

Spear, M., Breakefield, X.O., Beltzer, J., Schuback, D., Weissleder, R., Pardo, F., Ladner, R. 2001. Isolation, characterization, and recovery of small peptide phage display epitopes selected against viable malignant glioma cells. Cancer Gene Therapy, 8:506-511.

Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, Messerli SM, McClatchey AI, Niwa-Kawakita M, Ratner N, Reilly KM, Zhu Y, Giovannini M. 2004. Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Res. 64:3718-24.

Takahashi C, Bronson RT, Socolovsky M, Contreras B, Lee Y, Jacks T, Noda M, Kucherlapati R, Ewen ME. 2003. Rb and N-ras function together to control differentitation in the mouse. Mol Cell Biol 23:5256-5268.

Tevosian SG, Albrecht KH, Crispino JD, Fujiwara Y, Eicher EM, Orkin SH. 2002. Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2. Development. 129:4627-34.

Velupillai P, Carroll J, and Benjamin TL. 2002 . Susceptibility to Polyomavirus-Induced Tumors in Inbred Mice: Role of Innate Immune Responses. Virol. 76:9657-9663.

Weber GF, Bronson RT, Hagan J, Cantor H, Schmitts R, mak TW. 2002. Absence of the CD44 gene prevents sarcoma metastasis. Cancer Res 15:2281-2286.

Yang A, Walker N, Bronson R, Kagland M, Oosterwegel M, Bonnin J, Vagner L, Bonnet T, Dikkes P, Sharpe A, McKeon F, Caput D. 2000. P73 deficient mice have neurological, pheromonal, and inflammatory defects but lack spontaneous tumors. Nature 404:99-103.

Yu C, Cantor AB, Yang H, Browne C, Wells RA, Fujiwara Y, Orkin SH. 2002. Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo. J Exp Med. 195:1387-95.

Zinkel SS, Ong CC, Ferguson DO, Iwasaki H, Akashi K, Bronson RT, Kutok JL, Alt FW, Korsmeyer SJ. 2003. Pro-apoptotic BID is required for myeloid homeostsis and tumor suppression. Genes Dev. 17:229-39.