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Core Facilities

Tumor Imaging Metrics



The mission of the Tumor Imaging Metrics Core (TIMC) is to provide standardized, consistent, and efficient radiological measurements to evaluate tumor response for DF/HCC clinical trials.

  • Make reliable, quantitative, longitudinal measurements (such as linear dimension, RECIST, volume, function, etc.) of lesions from serial MRI, CT, and PET scan images
  • Present results of analyses on a password protected secure web-based report
  • Provide an independent service, with verifiable measurement of treatment response for patients enrolled in cancer center trials
  • Serve as a centralized, computerized resource to facilitate efficient internal or external auditing

Reliable tracking of changes in lesion size or function is essential for clinical trials that use radiological measurements as surrogate endpoints. The Tumor Metrics Core provides a service for managing these images, making measurements in a routine, reliable, and centralized way, and making results available to investigators efficiently.


Co-Director: Annick D. Van den Abbeele M.D. (DFCI)
Co-Director: Gordon J. Harris Ph.D. (MGH)

Project Manager: William Hanlon (MGH)
Director of Quality Control: Cheryl Sadow, M.D. (BWH)
Lead Image Analyst: Trinity Urban (MGH)


Massachusetts General Hospital, 3D Imaging Service
Brigham and Women's Hospital, 3D and Image Processing Center
Dana-Farber Cancer Institute, Department of Radiology, Division of Nuclear Medicine