Selected Scientific Publications

Original Articles:

Allen AM, Haddad RI, Tishler RI Retropharyngeal Nodes in Hypopharynx Cancer on Positron Emission Tomography JCO, 2007;25(5)—599-601.

Tishler RB, Posner MR, Norris CM, Jr., et al: Concurrent weekly docetaxel and concomitant boost radiation therapy in the treatment of locally advanced squamous cancer of the head and neck. Int. J. Radiation Oncology Biol. Phys., Vol. 65(4), 1036-44, 2006

Posner MR, With LJ: Cetuximab and radiotherapy for head and neck cancer. N Engl J Med, 2006 254:634-36

Posner MR, Hershock D, Blajman C, Mieckiwicz E, Winquist E, Gorbounova V, Tjulandin S, Shin D, Cullen K, Ervin T, Murphy BA, Raez LE, Cohen RB, Spaulding M, Tishler RB, Roth B, Viroglio RC, Venkatesan V, Romanov I, Agarwala S, Harter KW, Dugan M, Cmelak A, Markoe A, Read P, Steinbrenner L, Colevas AD, Norris CM, Haddad RI for the TAX 324 Group. Cisplatinum and fluorouracil alone or with docetaxel for head and neck cancer. New England Journal of Medicine, 2007, 357:1705-1715

Pennell NA, Daniels GH, Haddad RI, Ross DS, Evans T, Wirth LJ, Fidias PH, Temel JS, Gurubhagavatula S, Heist RS, Clark JR, Lynch TJ. A Phase II Study of Gefitinib in Patients with Advanced Thyroid Cancer. Thyroid. 2008; 18(3):317-23.

Haddad RI, Shin DM. Recent advances in head and neck cancer. NEJM. 2008; 359 (11):1143.

Haddad R, Crum C, Chen Z, Posner M, Krane J,  Li L, Burk R. HPV 16 transmission between a couple with HPV related head and neck cancer. Oral Oncology, 2008, 44:812-815

Salama J, Haddad R, Kies M, Busse P, Dong L, Brizel D, Eisbruch A, Tishler R, Trotti A, Garden A. Clinical Practice Guidance For Radiotherapy Planning Following Induction Chemotherapy In Locoregionally Advanced Head And Neck Cancer . International Journal of Radiation Oncology, Biology, Physics. 2009;In Press

Marsit CJ, Black CC, Posner MR, Kelsey KK. A genotype-phenotype examination of cyclin D1 on risk and outcome on squamous cell cancer of the head and neck  Clinical Cancer Research,  2008, 14:2371-2377.

Caglar HB, Tishler RB, Othus M, Burke E, Li Y, Goguen L, Wirth LJ, Haddad RI, Norris CM, Court LE, Annino DJ, Posner MR, Allen AM. Dose to the larynx predicts for swallowing complications following IMRT. International Journal of Radiation Oncology, Biology and Physics,, 2008;  72:1110-1118

Duval M, Posner MR, Cavacini LA. Neutrophil mediated destruction of HIV directed by a broadly reactive anti-HIV and anti-CD89 bispecific antibody. Journal of Virology, 2008, 82:4671-4674.

Wirth LJ, Krane JF, Li Y, Othus M, Moran AE, Dorfman DM, Norris CM, Goguen L, Posner MR, Haddad RI, Bertagnolli M. A pilot surrogate endpoint biomarker study of celecoxib in oral premalignant lesions. Cancer Prevention Research, 2008, 1: 339-348.

Marsit CJ, Posner MR, McClean MD, Kelsey KT. Hypermethylation of E-cadherin is an independent predictor of improved survival in head and neck squamous cell carcinoma. Cancer,, 2008; 113: 1566-1571

Furniss CS, McClean M, Smith JF, Bryan J, Applebaum K, Nelson HH, Posner MR, Kelsey KT. Human Papillomavirus 6 seropositivity is associated with head and neck squamous cell carcinoma, independent of tobacco and alcohol use. Annals of Oncology, Ann Oncol 2009;20(3):534-541.

Posner MR, Norris CM, Wirth LJ, Shin DM, Cullen KJ, Winquist EW, Blajman CR, Mickiewicz EA, Frennette GP, Pliner LF, Cohen RG, Steinbrenner LM, Freue JM,  Gorbunova VA, Tjulandin SA, Raez LE, Adkins DR, Tishler RB, Sarlis NJ, Haddad RI for the TAX 324 Study Group. Sequential Therapy for the Locally Advanced Larynx and Hypopharynx Cancer Subgroup in Tax 324: Survival, Surgery, and Organ Preservation, Annals of Oncology, 2008, in press

Parthan A, Posner MR, Brammer C, Beltran P,  Jansen J. Cost-utility of Docetaxel as Induction Chemotherapy followed by Chemoradiation in Locally Advanced Squamous Cell Carcinoma of Head and Neck. Head and Neck, 2008, in Press

Marsit CJ, Christensen BC, Houseman EA, Karagas MR, Wrensch MR, Yeh R, Nelson HH, Wiemels JL, Zheng S, Posner MR, McClean MD, Wienecke JK, Kelsey KT. Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma. Carcinogenesis, 2008, Carcinogenesis 2009;30(3):416-422..

Allen AM, Wolfsberger L, Tishler RB, Court LE.  Options for Combining Altered Fractionation with IMRT.  Technol Cancer Res Treat 2008; 7: 457-62. 

Elting LS, Keefe DM, Sonis ST, Garden AS, Spijkervet FK, Barasch A, Tishler RB, Canty TP, Kudrimoti MK, Vera-Llonch M; Burden of Illness Head and Neck Writing Committee. Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy: demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life.  Cancer 2008; 113: 2704-13.

Court LE, Wolfsberger L, Allen AM, James S, Tishler RB. Clinical experience of the importance of daily portal imaging for head and neck IMRT treatments.  J Appl Clin Med Phys 2008; 9: 2756.

Court LE, Tishler R, Xiang H, Allen AM, Makrigiorgos M, Chin L. Experimental evaluation of the accuracy of skin dose calculation for a commercial treatment planning system.  J Appl Clin Med Phys 2008; 9: 2792.

Fogg MH, Wirth LJ, Posner M, Wang F. Decreased EBNA-1-specific CD8+ T cells in patients with Epstein-Barr virus-associated nasopharyngeal carcinoma. Proc Natl Acad Sci U S A 2009;106(9):3318-23.

Chen A, Marsit C, Christensen BC,  Houseman EA, McClean M, Smith JF, Bryan J, Posner MR, Nelson HH, Kelsey KT. Variation in the vitamin C transporter, SLC23A2, and risk of HPV-16 associated head and neck cancer. Carcinogenesis, 2009, In Press.

Haddad RI,  Allen A, Wirth LJ, Goguen L, Annino D, Norris CM, Posner MR, Tishler RB. A randomized Phase II study of concomitant chemoradiotherapy using weekly carboplatin/paclitaxel with or without daily subcutaneous Amifostine in patients with locally advanced head and neck cancer. Cancer, In Press, 2009.

Non-Peer Reviewed Articles:

Wirth L and Kies M. Adjuvant Chemoradiotherapy for High-Risk Head and Neck Cancer. In: Jennifer Shin, Greg Randolph, and Chris Hartnick, editors. Evidence-Based Otolaryngology in press. New York, NY: Springer SBM; 2008.

Wirth L and Kies M. Chemoradiotherapy for Locally-Advanced Head and Neck Cancer. In: Jennifer Shin, Greg Randolph, and Chris Hartnick, editors. Evidence-Based Otolaryngology in press. New York, NY: Springer SBM; 2008.

Wirth L and Kies M. Nonsurgical Treatment for Laryngeal Carcinoma. In: Jennifer Shin, Greg Randolph, and Chris Hartnick, editors. Evidence-Based Otolaryngology in press. New York, NY: Springer SBM; 2008.

Wirth L and Kies M. Treatment of Recurrent and/or Metastatic Head and Neck Cancer. In: Jennifer Shin, Greg Randolph, and Chris Hartnick, editors. Evidence-Based Otolaryngology in press. New York, NY: Springer SBM; 2008.

Posner MR, Vermorken JB. Induction chemotherapy in the modern era of combined modality therapy for locally advanced head and neck cancer. Seminars in Oncology, 2008, 35 221-228.

Posner MR, Haddad RI, Tishler RB. Reply to Letters to the Editor. Treatment of Head and Neck Cancer. New England Journal of Medicine, 2008, 358:1077-1078.

Haddad RI and Posner MR.  Cisplatin, 5-fluorouracil, and docetaxel in locally advanced head and neck cancer. American Journal of Hematology /Oncology, 2008, 7:28-32.

Lorch JH, Posner MR, Wirth LJ, Haddad RI. Seeking alternative biological therapies: The future of targeted molecular treatment. Oral Oncology, In press, 2008

Russo G, Haddad RI, Posner MR, Machtay M. Radiation treatment breaks and ulcerative mucositis in head and neck cancer. The Oncologist, 2008; 13(8):886-898.

Forastiere, AA, Ang KK, Brizel D, Brockstein BE, Burtness BA, Cmelak AJ, Colevas AD, Dunphy F, Eisele DW, Goepfert H, Hicks WL, Jr, Kies MS, Lydiatt WM, Maghami E, Martins R, McCaffrey T, Mittal BB, Pfister DG, Pinto HA, Posner MR, Ridge JA, Samant S, Schuller DE, Shah JP, Spencer S, Trotti A, 3rd, Weber RS, Wolf GT, and Worden F. Head and neck cancers. Journal of the National Comprehensive Cancer Network, 2008, 6: 646-695

Lorch JH, Posner M, Haddad RI. Induction chemotherapy in locally advanced head and neck cancer. A new standard of care? Hematol Oncol Clin North Am. 2008; 22(6): 1155-63.

Haddad R, Annino D, Tishler RB. Multidisciplinary approach to cancer treatment: focus on head and neck cancer. Dent Clin North Am. 2008; 52(1):1-17

Haddad R. Trends in Head and Neck Cancer. The American Journal of Hematology/Oncology. 2008; 7(8): 323-324.

Boshoff C and Posner MR. Targeting EGFr in head and neck cancer: A decade of progress. Nature Clinical Practice Oncology, 2009, 6:123