Program Leadership

Leader: Jeffrey E. Settleman, Ph.D.
Co-Leader: Karen Cichowski, Ph.D.

Cancer Cell Biology Program

The Cancer Cell Biology (CCB) Program focuses on cell death (apoptosis), cell division (cell-cycle control), and cellular differentiation. The CCB Program performs high-quality basic research that provides mechanistic insights into cancer causation. These studies may help identify new molecular targets that could be used in the development of novel diagnostics or therapeutics.

The CCB Program is devoted to basic and translational studies that impact patient care; it also provides a strong basic science foundation for the research initiatives of clinical colleagues in the DF/HCC disease-based programs.

The Program has four specific aims:


Status:

Active

Type:

Discipline

Discipline:

Basic Science
Image of prostate cancer (provided by Massimo Loda): tumor suppressor gene PTEN in the normal mucosa (brown, left) and complete loss in the tumor glands (right). Loss of PTEN results in PI3K activation.