Services

Services offered by the Core include the following:

• Experimental design and protocol development
• Preparation of dosing and sample collection case report forms and sample labels
• Establishing and implementing appropriate procedures for sample handling, processing, and storage prior to analysis
• Sample storage and tracking
• Study oversight
• The development, validation, and application of analytical methods to measure drugs and their metabolites in biological fluids
• Metabolite identification
• PK data analysis and interpretation
• Correlation analyses to assess the influence of pathophysiologic variables on PK parameters and associations between PK parameters and biological effects such as toxicity, biological correlates, and therapeutic response
• Assistance in the preparation of manuscripts and presentations