Project 1: Modifiable risk factors and gene/environmental interactions in ovarian cancer
Principal Investigators: Susan Hankinson, MPH, ScD (HSPH) and Daniel W. Cramer, MD, ScD (BWH)
Co-Investigators: Immaculata DeVivo, MPH, PhD (BWH) and Linda Titus-Ernstoff, PhD (Norris Cotton Cancer Center)
Project 2: Genetic changes in early stage ovarian cancer
Principal Investigators: Samuel Mok, PhD (BWH) and Ross Berkowitz, MD (BWH)
Co-Investigators: Michael Birrer, MD (NCI); John Blessing, PhD (Roswell Park Cancer Institute); Cynthia Morton, PhD (BWH); and Eugene Sobel, PhD (Roswell Park Cancer Institute)
Project 3: Identifying novel biomarkers of ovarian cancer with application to high risk women undergoing risk reducing salpingo oophorectomy
Principal Investigator: Steven Skates, PhD (MGH)
Co-Investigator: Ronny Drapkin, MD, PhD (DFCI)
Project 4: Defining clinical response genes and proteins in high-risk epithelial ovarian carcinoma
Principal Investigators: Stephen Cannistra, MD (BIDMC) and Alan D’Andrea, MD (DFCI)
Project 5: Novel immunotherapeutic approaches for ovarian cancer
Principal Investigators: Donald Kufe, MD (DFCI) and David Avigan, MD (BIDMC)