Latest News and Announcements

  • July 30, 2015 – Funding

    The Bridge Project is a collaboration between Dana-Farber/Harvard Cancer Center and the Koch Institute, designed to bring advanced bioengineering in cancer science and clinical oncology research together to solve today’s...

  • July 30, 2015 – Funding

    Three pilot projects in the amount of $65,000 per year for up to 2 years will be awarded. The anticipated award date is November 1, 2015.

  • July 24, 2015 – Funding

    The DF/HCC Ovarian Cancer program is soliciting project proposals for an ovarian cancer SPORE application. Funding will be provided through the P50 Research Center Grants for Specialized Programs of Research Excellence...

  • July 14, 2015 – Announcements

    July 2015 | The NIH continues to recognize DF/HCC as a leader in cancer research by awarding funding to a number of our research initiatives. Recently, this funding included the following new highly collaborative grants:...

Publications

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  • Li W, Reátegui E, Park MH, Castleberry S, Deng JZ, Hsu B, Mayner S, Jensen AE, Sequist LV, Maheswaran S, Haber DA, Toner M, Stott SL, Hammond PT. Biodegradable nano-films for capture and non-invasive release of circulating tumor cells. Biomaterials 2015; 65:93-102. PubMed
  • Beckers A, Van Peer G, Carter DR, Gartlgruber M, Herrmann C, Agarwal S, Helsmoortel HH, Althoff K, Molenaar JJ, Cheung BB, Schulte JH, Benoit Y, Shohet JM, Westermann F, Marshall GM, Vandesompele J, De Preter K, Speleman F. MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma. Cancer Lett 2015; 366:123-32. PubMed
  • Felix AS, Brinton LA, McMeekin DS, Creasman WT, Mutch D, Cohn DE, Walker JL, Moore RG, Downs LS, Soslow RA, Zaino R, Sherman ME. Relationships of Tubal Ligation to Endometrial Carcinoma Stage and Mortality in the NRG Oncology/ Gynecologic Oncology Group 210 Trial. Journal of the National Cancer Institute 2015. PubMed
  • Jeong HS, Jones D, Liao S, Wattson DA, Cui CH, Duda DG, Willett CG, Jain RK, Padera TP. Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases. Journal of the National Cancer Institute 2015. PubMed
  • Li J, Zhang H, Wang L, Yang C, Lai H, Zhang W, Chen X, Wang J. Comparative study of IDH1 mutations in gliomas by high resolution melting analysis, immunohistochemistry and direct DNA sequencing. 2015; 12:4376-81. PubMed
  • Zhu L, Liu R, Zhang W, Qian S, Wang JH. MicroRNA-205 regulates ubiquitin specific peptidase 7 protein expression in hepatocellular carcinoma cells. 2015; 12:4652-6. PubMed
  • Ligibel JA, Cirrincione CT, Liu M, Citron M, Ingle JN, Gradishar W, Martino S, Sikov W, Michaelson R, Mardis E, Perou CM, Ellis M, Winer E, Hudis CA, Berry D, Barry WT. Body Mass Index, PAM50 Subtype, and Outcomes in Node-Positive Breast Cancer: CALGB 9741 (Alliance). Journal of the National Cancer Institute 2015. PubMed
  • Zeigler-Johnson C, Morales KH, Glanz K, Spangler E, Mitchell J, Rebbeck TR. Individual- and neighborhood-level education influences the effect of obesity on prostate cancer treatment failure after prostatectomy. Cancer Causes Control 2015; 26:1329-37. PubMed
  • Lim SM, Xie T, Westover KD, Ficarro SB, Tae HS, Gurbani D, Sim T, Marto JA, Jänne PA, Crews CM, Gray NS. Development of small molecules targeting the pseudokinase Her3. Bioorg Med Chem Lett 2015; 25:3382-9. PubMed
  • Huang J, Wang L, Cong Z, Amoozgar Z, Kiner E, Xing D, Orsulic S, Matulonis U, Goldberg MS. The PARP1 inhibitor BMN 673 exhibits immunoregulatory effects in a Brca1(-/-) murine model of ovarian cancer. Biochem Biophys Res Commun 2015; 463:551-6. PubMed
  • Zhao JJ, Chu ZB, Hu Y, Lin J, Wang Z, Jiang M, Chen M, Wang X, Kang Y, Zhou Y, Ní Chonghaile T, Johncilla ME, Tai YT, Cheng JQ, Letai A, Munshi NC, Anderson KC, Carrasco RD. Targeting the miR-221-222/PUMA/BAK/BAX pathway abrogates dexamethasone resistance in multiple myeloma. Cancer Res 2015. PubMed
  • Stone JH, Carruthers MN, Topazian MD, Khosroshahi A, Witzig TE, Wallace ZS, Hart PA, Deshpande V, Smyrk TC, Chari S. Response to: 'Is rituximab effective for IgG4-related disease in the long term? Experience of cases treated with rituximab for 4 years' by Yamamoto et al. Ann Rheum Dis 2015; 74:e47. PubMed
  • Jones M, Chebib I, Deshpande V, Nielsen GP. Radiation-Associated Low-Grade Extraskeletal Osteosarcoma of the Neck Following Treatment for Thyroid Cancer. Int J Surg Pathol 2015; 23:384-7. PubMed
  • Shiramizu B, Goldman S, Smith L, Agsalda-Garcia M, Galardy P, Perkins SL, Frazer JK, Sanger W, Anderson JR, Gross TG, Weinstein H, Harrison L, Barth MJ, Mussolin L, Cairo MS. Impact of persistent minimal residual disease post-consolidation therapy in children and adolescents with advanced Burkitt leukaemia: a Children's Oncology Group Pilot Study Report. British Journal of Haematology 2015; 170:367-71. PubMed
  • Jegadeesh N, Liu Y, Prabhu RS, Magliocca KR, Marcus DM, Higgins KA, Vainshtein JM, Trad Wadsworth J, Beitler JJ. Outcomes and prognostic factors in modern era management of major salivary gland cancer. Oral Oncol 2015; 51:770-7. PubMed
  • Sorror ML, Logan BR, Zhu X, Rizzo JD, Cooke KR, McCarthy PL, Ho VT, Horowitz MM, Pasquini MC. Prospective Validation of the Predictive Power of the Hematopoietic Cell Transplantation Comorbidity Index: A Center for International Blood and Marrow Transplant Research Study. Biol Blood Marrow Transplant 2015; 21:1479-87. PubMed
  • Betensky RA. Measures of follow-up in time-to-event studies: Why provide them and what should they be? Clin Trials 2015; 12:403-8. PubMed
  • Kassam A, Skiadaresis J, Alexander S, Wolfe J. Differences in end-of-life communication for children with advanced cancer who were referred to a palliative care team. Pediatr Blood Cancer 2015; 62:1409-13. PubMed
  • Boeke CE, Tamimi RM, Berkey CS, Colditz GA, Giovannucci E, Malspeis S, Willett WC, Frazier AL. Adolescent dietary vitamin D and sun exposure in relation to benign breast disease. Cancer Causes Control 2015; 26:1181-7. PubMed
  • Schmid M, Sood A, Campbell L, Kapoor V, Dalela D, Klett DE, Chun FK, Kibel AS, Sammon JD, Menon M, Fisch M, Trinh QD. Impact of smoking on perioperative outcomes after major surgery. Am J Surg 2015; 210:221-229.e6. PubMed
  • Ng K, Chan AT, Fuchs CS. Response. Journal of the National Cancer Institute 2015. PubMed
  • Nipp RD, Ryan DP. Predicting a response to FOLFIRINOX in pancreatic cancer. Journal of the National Cancer Institute 2015. PubMed
  • Van Blarigan EL, Kenfield SA, Yang M, Sesso HD, Ma J, Stampfer MJ, Chan JM, Chavarro JE. Fat intake after prostate cancer diagnosis and mortality in the Physicians' Health Study. Cancer Causes Control 2015; 26:1117-26. PubMed
  • Cheney MD, Zhang D, Chen MH, Loffredo MJ, Richie JP, D'Amico AV. Greatest Percentage Involved Core Length and Risk of Clinically Significant Prostate-Specific Antigen Failure After Radical Prostatectomy. Clin Genitourin Cancer 2015; 13:338-43. PubMed
  • Bulger AL, Mayer JE, Gershenwald JE, Guild SR, Gottlieb MA, Geller AC. Enforcement Provisions of Indoor Tanning Bans for Minors: An Analysis of the First 6 US States. Am J Public Health 2015; 105:e10-2. PubMed
  • Chandra RA, Chen MH, Zhang D, Loffredo M, D'Amico AV. Age, Comorbidity, and the Risk of Prostate Cancer-Specific Mortality in Men With Biopsy Gleason Score 4+3: Implications on Patient Selection for Multiparametric MRI. Clin Genitourin Cancer 2015; 13:400-5. PubMed
  • Gilkey MB, Moss JL, Coyne-Beasley T, Hall ME, Shah PD, Brewer NT. Physician communication about adolescent vaccination: How is human papillomavirus vaccine different? Prev Med 2015; 77:181-5. PubMed
  • Esain V, Kwan W, Carroll KJ, Cortes M, Liu SY, Frechette GM, Sheward LM, Nissim S, Goessling W, North TE. Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity. Stem Cells 2015; 33:2596-612. PubMed
  • Chan SS, Wong DC, Cheung YT, Leung DY, Lau L, Lai V, Lam TH. A block randomized controlled trial of a brief smoking cessation counselling and advice through short message service on participants who joined the Quit to Win Contest in Hong Kong. 2015; 30:609-21. PubMed
  • Park SW, Lee HL, Doo EY, Lee KN, Jun DW, Lee OY, Han DS, Yoon BC, Choi HS, Lee KH. Visceral Obesity Predicts Fewer Lymph Node Metastases and Better Overall Survival in Colon Cancer. J Gastrointest Surg 2015; 19:1513-21. PubMed
  • Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L. Interventions to Slow Aging in Humans: Are We Ready? Aging Cell 2015; 14:497-510. PubMed
  • Rahman R, Catalano PJ, Reardon DA, Norden AD, Wen PY, Lee EQ, Nayak L, Beroukhim R, Dunn IF, Golby AJ, Johnson MD, Chiocca EA, Claus EB, Alexander BM, Arvold ND. Incidence, risk factors, and reasons for hospitalization among glioblastoma patients receiving chemoradiation. J. Neurooncol. 2015; 124:137-46. PubMed
  • Prados MD, Byron SA, Tran NL, Phillips JJ, Molinaro AM, Ligon KL, Wen PY, Kuhn JG, Mellinghoff IK, de Groot JF, Colman H, Cloughesy TF, Chang SM, Ryken TC, Tembe WD, Kiefer JA, Berens ME, Craig DW, Carpten JD, Trent JM. Toward precision medicine in glioblastoma: the promise and the challenges. 2015; 17:1051-63. PubMed
  • Li HW, Andreola G, Carlson AL, Shao S, Lin CP, Zhao G, Sykes M. Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation. J Immunol 2015; 195:1282-92. PubMed
  • Schrauwen P, van Marken Lichtenbelt WD, Spiegelman BM. The future of brown adipose tissues in the treatment of type 2 diabetes. Diabetologia 2015; 58:1704-7. PubMed
  • Vaughn JE, Storer BE, Armand P, Raimondi R, Gibson C, Rambaldi A, Ciceri F, Oneto R, Bruno B, Martin PJ, Sandmaier BM, Storb R, Sorror ML. Design and Validation of an Augmented Hematopoietic Cell Transplantation-Comorbidity Index Comprising Pretransplant Ferritin, Albumin, and Platelet Count for Prediction of Outcomes after Allogeneic Transplantation. Biol Blood Marrow Transplant 2015; 21:1418-24. PubMed
  • Redjal N, Agarwalla PK, Dietrich J, Dinevski N, Stemmer-Rachamimov A, Nahed BV, Loeffler JS. Remote acute demyelination after focal proton radiation therapy for optic nerve meningioma. J Clin Neurosci 2015; 22:1367-9. PubMed
  • Kojić N, Milošević M, Petrović D, Isailović V, Sarioglu AF, Haber DA, Kojić M, Toner M. A computational study of circulating large tumor cells traversing microvessels. 2015; 63:187-95. PubMed
  • Amri R, Bordeianou LG, Sylla P, Berger DL. Variations in Metastasis Site by Primary Location in Colon Cancer. J Gastrointest Surg 2015; 19:1522-7. PubMed
  • Anderson KS, Gerber JE, D'Souza G, Pai SI, Cheng JN, Alam R, Kesiraju S, Chowell D, Gross ND, Haddad R, Gillison ML, Posner M. Biologic predictors of serologic responses to HPV in oropharyngeal cancer: The HOTSPOT study. Oral Oncol 2015; 51:751-8. PubMed
  • Martin PJ, Lee SJ, Przepiorka D, Horowitz MM, Koreth J, Vogelsang GB, Walker I, Carpenter PA, Griffith LM, Akpek G, Mohty M, Wolff D, Pavletic SZ, Cutler CS. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: VI. The 2014 Clinical Trial Design Working Group Report. Biol Blood Marrow Transplant 2015; 21:1343-59. PubMed
  • Montesinos-Rongen M, Purschke FG, Brunn A, May C, Nordhoff E, Marcus K, Deckert M. Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins. J Immunol 2015; 195:1312-9. PubMed
  • Betensky RA, Szymonifka J, Lee EQ, Nutt CL, Batchelor TT. Computationally simple analysis of matched, outcome-based studies of ordinal disease states. Stat Med 2015; 34:2514-27. PubMed
  • Black JC, Whetstine JR. Too little O2 Too much gain. Cell Cycle 2015. PubMed
  • Nichols RJ, Higgins SJ. Single-Molecule Electronics: Chemical and Analytical Perspectives. Annu Rev Anal Chem (Palo Alto Calif) 2015; 8:389-417. PubMed
  • Yamoah K, Johnson MH, Choeurng V, Faisal FA, Yousefi K, Haddad Z, Ross AE, Alshalafa M, Den R, Lal P, Feldman M, Dicker AP, Klein EA, Davicioni E, Rebbeck TR, Schaeffer EM. Novel Biomarker Signature That May Predict Aggressive Disease in African American Men With Prostate Cancer. J Clin Oncol 2015. PubMed
  • Flaherty KT, Manola JB, Pins M, McDermott DF, Atkins MB, Dutcher JJ, George DJ, Margolin KA, DiPaola RS. BEST: A Randomized Phase II Study of Vascular Endothelial Growth Factor, RAF Kinase, and Mammalian Target of Rapamycin Combination Targeted Therapy With Bevacizumab, Sorafenib, and Temsirolimus in Advanced Renal Cell Carcinoma-A Trial of the ECOG-ACRIN Ca J Clin Oncol 2015; 33:2384-91. PubMed
  • Sineshaw HM, Freedman RA, Ward EM, Flanders WD, Jemal A. Black/White Disparities in Receipt of Treatment and Survival Among Men With Early-Stage Breast Cancer. J Clin Oncol 2015; 33:2337-44. PubMed
  • Hyun H, Owens EA, Wada H, Levitz A, Park G, Park MH, Frangioni JV, Henary M, Choi HS. Cartilage-Specific Near-Infrared Fluorophores for Biomedical Imaging. Angew Chem Int Ed Engl 2015; 54:8648-52. PubMed
  • Sparano JA, Zhao F, Martino S, Ligibel JA, Perez EA, Saphner T, Wolff AC, Sledge GW, Wood WC, Davidson NE. Long-Term Follow-Up of the E1199 Phase III Trial Evaluating the Role of Taxane and Schedule in Operable Breast Cancer. J Clin Oncol 2015; 33:2353-60. PubMed
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