DF/HCC SPORE in Prostate Cancer Translational Projects/Cores

August 04, 2016


DF/HCC SPORE in Prostate Cancer
Competing Renewal

PIs: Massimo Loda, MD (DFCI), Steven Balk, MD, PhD (BIDMC)

REQUEST FOR APPLICATIONS: NEW Translational Projects In Prostate Cancer

AWARD AMOUNT: Up to 5 awards, up to $150,000 (direct costs) per year for up to 5 years
APPLICATION DEADLINE: On or before Monday, August 15, 2016
ANTICIPATED AWARD DATE: July 1, 2018
(Please note that January 1, 2018 was previously listed. July 1, 2018 is the corrected anticipated award date)

The Dana-Farber / Harvard Cancer Center (DF/HCC) Specialized Program in Research Excellence (SPORE) in Prostate Cancer is currently seeking applications for Translational Projects or Cores in Prostate Cancer.

The applicant (PI) or co-PI must be on the faculty at Harvard Medical School or Harvard School of Public Health at the level of Assistant Professor or higher. Research may span the disciplines of basic biology, population science, or clinical science including imaging. Proposals will be accepted from investigators leading existing projects and pilot projects as well as currently non-SPORE funded investigators. All basic research supported by the SPORE must have a plan for translation into application or studies in humans, since the purpose of this program is to promote translational research in prostate cancer. Similarly all clinical research needs to have a strong wet or dry lab component. As such, basic or population scientists need to partner with clinical scientists to ensure a plan for clinical application. Collaboration between investigators currently working in this field is strongly encouraged.

We are seeking pre-applications in the form of a 1-page proposal that contains background, specific aims, research plan and plans for translation (see below). These pre-applications will be judged on their scientific merit, translational potential and the potential for contribution to the overall status of the DF/HCC Prostate Cancer Program/Prostate Cancer SPORE. Some pre-applications may be selected to present their proposal at a project review session (time and place to be determined). Up to 5 projects may ultimately be selected for inclusion in the next SPORE competitive renewal. This award will be granted at a level up to $150k in yearly direct costs for up to 5 years (likely start date 07/01/2018). The awardees will become members of the DF/HCC Prostate Cancer Program and the DF/HCC Prostate Cancer SPORE and would be expected to attend SPORE activities (meetings, retreats, research presentations). Women and minority candidates are encouraged to apply.

Applications are due August 15, 2016, and should consist of the following:

1) NIH Biosketch of all key personnel
2) Current Other Support pages for all key personnel
3) A brief research proposal of approximately 1 page that is structured as follows:
     A. Background
     B. Specific Aims
     C. Research Plan
     D. Plan for Translation to Clinical Application.
4) Appendix with reprints etc. are permitted

Application Submission Instructions: One PDF document including the above required documentation should be emailed to Meredith_Smith@dfci.harvard.edu by August 15, 2016. For all inquiries, please contact Meredith Smith by email or phone (617.632.4705).