To encourage the formation of cross-disciplinary teams, we regularly hold informational sessions, workshops, and symposia based on complex translational problems in cancer. Check below for information about upcoming Bridge Project opportunities and events, or click the listings to the left to view videos from previous events.

Past Bridge Project Events

2016

2016 Bridge Project Request for Applications

Download the 2016 Bridge Project RFA here.

Letter of Intent deadline: September 30, 2016

Please send an email to ki-bridge@mit.edu that includes the names and affiliations of your Bridge Project proposal team members, a title and a brief description of your proposal.

Proposal submission deadline: October 20, 2016 at 5 p.m.

The review committee meeting, at which finalists present as a team, will take place on December 13, 2016. All team members must be available that day for an in-person interview. If your team members cannot make this date, or have time restrictions, please let us know when you submit your letter of intent. 

July 12, 2016: Off-Cycle Bridge Project RFA Information Session - Pediatric Brain Tumor Research

Click here to view the event details

 

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2015

September 2015: Bridge Project RFA Information Session

On September 8, 2015, David Livingston, deputy director of Dana-Farber/Harvard Cancer Center, and Tyler Jacks, director of the Koch Institute, announced details of the new and expanded 2015 Bridge Project RFA. This event also featured presentations by successful Bridge Project awardees and highlighted information and resources that may benefit teams' application packages. Click here to view the full RFA, and watch presentations from the evening's program below:

ANNOUNCEMENT OF EXPANDED 2015 RFA & APPLICATION TIPS 

David Livingston, MD (DFCI), Tyler Jacks, PhD(Koch)

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NEW AREA OF INTEREST: LEIOMYOSARCOMA 

George Demetri, MD (DFCI)

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NEW AREA OF INTEREST: MULTIPLE MYELOMA 

Nikhil Munshi, MD (DFCI)

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ENGINEERING ASSETS

K. Dane Wittrup, PhD (Koch)

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2014

May 2014: Bridging the Gap in Pancreatic Cancer

On May 29, 2014, the Koch Institute's with/in/sight lecture series showcased the work of the Bridge Project. With introductory remarks by Anne Deconinck and Bridge Project co-leader Tyler Jacks, the event offered a clinician's perspective on the challenges of pancreatic cancer and examples of Bridge Project-funded research focused on developing novel approaches and technologies for its treatment. Click here to view photos from evening's program or view the presentations below:

Introduction

Anne Deconinck (Koch) and Tyler Jacks, PhD(Koch)

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Elazer Edelman, MD, PhD (Koch) (video not available)

May 2014: Building Bridges Symposium and Networking Event

This event held on May 22, 2014, included the announcement of newly awarded Bridge Project Teams and presentations by two of last year's winning teams, as well as experts in the three newly added research areas of interest. Participants learned about new opportunities associated with the Bridge Project and networked with colleagues to build bridges toward future collaboration. View selected videos from the event below.

Speakers and Presentations

Introduction to Bridge Project 2014

David Livingston, MD (DFCI)
Tyler Jacks, PhD (Koch)

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Bridge to Success

Targeting Mutant IDH1 in Malignant Gliomas, a collaboration between MatthewVanderHeiden,MD,PhD (Koch), WilliamKaelin,MD (DFCI), and DanielCahill,MD,PhD (MGH)

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Osmotic Micro-Pump as Delivery System for Intraperitoneal Chemotherapy in the Treatment of Advanced Ovarian Cancer, a collaboration between, Michael Birrer, MD, PhD (MGH), Marcela Del Carmen, MD (MGH), and Michael Cima, PhD (Koch)

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CachexiaAlfred Goldberg, PhD (HMS)

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Cancers with Viral EtiologyJames DeCaprio, MD (DFCI)

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New Technologies for Tumor MonitoringPeter Ghoroghchian, MD, PhD (Koch)

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Closing Remarks

Tyler Jacks, PhD (Koch)
David Livingston, MD (DFCI)

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2013

June 2013: Bridge Project Technology Workshop

During this program, which took place on June 27, 2013, engineers from MIT and the Koch Institute presented new technologies for cancer diagnosis and drug development. The aim of the session was to stimulate new collaborations between MIT and the Koch Institute scientists and engineers with DF/HCC members, in preparation for the 2014 round of Bridge funding.

Speakers and Presentations

Opening Remarks

David Livingston, MD (DFCI)

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Early Detection/Diagnostics

Barbara Imperiali, PhD(MIT)

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Systems Biology

Doug Lauffenburger, PhD (Koch)

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May 2013: Cancer Treatment Challenges Symposium/Roundtable

At this May 6, 2013 event, cancer biologists, engineers, and clinicians gathered at the Koch Institute at MIT for an open discussion of the greatest challenges and most promising solutions in cancer care.

Hear highlights from the discussion in the video below:

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Speakers and Presentations

Catherine Wu, MD (DFCI/MGH)
Matthew Smith, MD, PhD (MGH)
Steven Balk, MD, PhD (BIDMC)
Phillip Sharp, PhD
(Koch)
Sangeeta Bhatia, MD, PhD (Koch)
K. Dane Wittrup, PhD (Koch)
Michael Yaffe, MD, PhD (Koch)

The event also featured presentations by researchers working on existing Bridge Project teams:

Novel Immunotherapies Against Pancreatic Cancer, a collaboration between KaiWucherpfennigMD, (DFCI), J. Christopher Love, PhD (Koch), and Hidde Ploegh, PhD (Whitehead/Koch)

A Pancreatobiliary Chemotherapy Eluting Stent for Pancreatic Ductal Adenocarcinomas, a collaboration between J(MGH) and Elazer Edelman, MD, PhD (Koch)

Angiotensin Receptor Blockers (ARBs) as a Novel Approach to Improve Drug Delivery in the Treatment of Pancreatic Cancer, a collaboration between Rakesh Jain, PhD (MGH) and Robert Langer, ScD (Koch)

Single-Cell Functional, Genomic and Transcriptomic Analysis in Glioblastoma, a collaboration between Keith Ligon, MD, PhD (DFCI) and J. Christopher Love, PhD (Koch)

March 2013: Bridge Project Awards Ceremony and Luncheon

The event, which took place on March 21, 2013, was hosted by MIT President L. Rafael Reif, PhD, and featured opening remarks by Reif, David Livingston, MD, Deputy Director of the DF/HCC, Tyler Jacks, PhD, Director of the Koch Institute, and David Nathan, MD, President Emeritus, Dana-Farber Cancer Institute. The award ceremony and luncheon included presentations by researchers working on the four newly awarded Bridge Project projects:

Presentations

Osmotic Micro-Pump as Delivery System for Intraperitoneal Chemotherapy in the Treatment of Advanced Ovarian Cancer, a collaboration between Michael Birrer, MD, PhD (MGH), Marcela Del Carmen, MD (MGH), and Michael Cima, PhD (Koch)

Developing Novel Therapeutic Approaches in Small Cell Lung Carcinoma Using Genetically Engineered Mouse Models and Human Circulating Tumor Cells, a collaboration between Tyler Jacks, PhD (Koch), Jeffrey Engelman, MD, PhD (MGH), and Daniel Haber, MD, PhD (MGH). Presented by Anna Farago, MD, PhD (Koch/MGH)

Detection of 'Invisible' Nevi in Redheads, a collaboration between David Fisher, MD, PhD (MGH), Peter So, PhD (MIT), and Conor Evans, PhD (MGH)

Targeting Mutant IDH1 in Malignant Gliomas, a collaboration between William Kaelin, Jr., MD (DFCI), Daniel Cahill, MD, PhD (MGH), and Matthew Vander Heiden, MD, PhD (Koch)

The event also featured a presentation from one of the existing Bridge Project teams:

A Pancreatobiliary Chemotherapy Eluting Stent for Pancreatic Ductal Adenocarcinomas, a collaboration between Jeffrey Clark, MD (MGH), Robert Langer, ScD (Koch), and Elazer Edelman, MD, PhD (Koch)

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2012

September 2012: Technology Workshop

This program, which took place on September 20, 2012, brought together engineers and technologists from across MIT and the Dana-Farber/Harvard Cancer Center to introduce tools and capabilities that could be used by collaborative teams to improve cancer treatment.

Speakers and Presentations

Introduction

David Livingston, MD (DFCI)

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Drug Delivery Presentations

Robert Langer, ScD (Koch)

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Early Detection/Diagnostics Presentations

Sangeeta Bhatia, MD, PhD(Koch)

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Systems Biology Presentations

Michael Yaffe, MD, PhD(Koch)

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Conclusion

David Livingston, MD (DFCI)

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July 2012: Melanoma Workshop

Understanding the Unmet Needs in Melanoma

On July 31, 2012 the Bridge Project invited scientists and engineers to talk with clinicians and form interdisciplinary teams to address pressing challenges in the field of melanoma research.

Clinician Presenters

David Fisher, MD, PhD(DFCI) (General Overview)
Keith Flaherty, MD (MGH) (Targeted Therapy)
Alan Geller MPH, RN (HSPH) (Early Detection-High Risk Identification)
Jennifer Wargo, MD (MGH) (Surgery)
Lyn Duncan, MD (MGH) (Dermatopathology)
Steven Hodi, MD (DFCI) (Melanoma and Immunotherapy)

July 2012: Ovarian Cancer Workshop

Understanding the Unmet Needs in Ovarian Cancer

On July 18, 2012 the Bridge Project invited scientists and engineers to talk with clinicians and form interdisciplinary teams to address pressing challenges in ovarian cancer research.

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May 2012: Lung Cancer Workshop

Understanding the Unmet Needs in Lung Cancer

On May 24, 2012 researchers, engineers, and clinicians gathered to discuss the clinical, translational, and basic science aspects of lung cancer and explore opportunities for interdisciplinary collaboration.

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Presenters

Yolonda Colson, MD, PhD (DFCI)
Tyler Jacks, PhD (Koch)
Matthew Meyerson, MD, PhD (DFCI) (not recorded)
Alice Shaw, MD, PhD (MGH/Koch)

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