Photo of Abram Recht,  MD

Abram Recht, MD

Beth Israel Deaconess Medical Center

Beth Israel Deaconess Medical Center
Phone: (617) 667-2345
Fax: (617) 667-4990

Abram Recht, MD

Beth Israel Deaconess Medical Center

EDUCATIONAL TITLES

  • Professor, Radiation Oncology, Harvard Medical School
  • Deputy Chief and Senior Radiation Oncologist, Radiation Therapy, Beth Israel Deaconess Medical Center

DF/HCC PROGRAM AFFILIATION

Research Abstract

Clinical research in all areas of local-regional treatment of breast cancer, with an emphasis on the use of conservative surgery and radiation therapy and the integration of systemic therapy and radiotherapy.

Publications

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  • Galland-Girodet S, Pashtan I, MacDonald SM, Ancukiewicz M, Hirsch AE, Kachnic LA, Specht M, Gadd M, Smith BL, Powell SN, Recht A, Taghian AG. Long-Term Cosmetic Outcomes and Toxicities of Proton Beam Therapy Compared With Photon-Based 3-Dimensional Conformal Accelerated Partial-Breast Irradiation: A Phase 1 Trial. Int J Radiat Oncol Biol Phys 2014. PubMed
  • Varlotto JM, Decamp MM, Flickinger JC, Lake J, Recht A, Belani CP, Reed MF, Toth JW, Mackley HB, Sciamanna CN, Lipton A, Ali SM, Mahraj RP, Gilbert CR, Yao N. Would screening for lung cancer benefit 75- to 84-year-old residents of the United States? 2014; 4:37. PubMed
  • Varlotto J, Fakiris A, Flickinger J, Medford-Davis L, Liss A, Shelkey J, Belani C, Deluca J, Recht A, Maheshwari N, Barriger R, Yao N, Decamp M. Matched-pair and propensity score comparisons of outcomes of patients with clinical stage I non-small cell lung cancer treated with resection or stereotactic radiosurgery. Cancer 2013. PubMed
  • Yao N, Mackley HB, Anderson RT, Recht A. Survival after partial breast brachytherapy in elderly patients with nonmetastatic breast cancer. Brachytherapy 2013. PubMed
  • Krishnan MS, Recht A, Bellon JR, Punglia RS. Trade-offs associated with axillary lymph node dissection with breast irradiation versus breast irradiation alone in patients with a positive sentinel node in relation to the risk of non-sentinel node involvement: implications of ACOSOG Z0011. Breast Cancer Res Treat 2013; 138:205-13. PubMed
  • Pashtan IM, Recht A, Ancukiewicz M, Brachtel E, Abi-Raad RF, D'Alessandro HA, Levy A, Wo JY, Hirsch AE, Kachnic LA, Goldberg S, Specht M, Gadd M, Smith BL, Powell SN, Taghian AG. External beam accelerated partial-breast irradiation using 32 gy in 8 twice-daily fractions: 5-year results of a prospective study. Int J Radiat Oncol Biol Phys 2012; 84:e271-7. PubMed
  • Solin LJ, Gray R, Goldstein LJ, Recht A, Baehner FL, Shak S, Badve S, Perez EA, Shulman LN, Martino S, Davidson NE, Sledge GW, Sparano JA. Prognostic value of biologic subtype and the 21-gene recurrence score relative to local recurrence after breast conservation treatment with radiation for early stage breast carcinoma: results from the Eastern Cooperative Oncology Group E2197 study. Breast Cancer Res Treat 2012; 134:683-92. PubMed
  • Recht A, Solin LJ. Breast-conserving surgery and radiotherapy in early-stage breast cancer: the importance of local control. Semin Radiat Oncol 2010; 21:3-9. PubMed
  • Recht A. Can Radiotherapy Replace Axillary Dissection for Patients with Positive Sentinel Nodes? Breast Dis 2010. PubMed
  • Varlotto JM, Medford-Davis LN, Recht A, Flickinger JC, Schaefer E, Decamp MM. Failure Rates and Patterns of Recurrence in Patients with Resected N1 Non-Small-Cell Lung Cancer. Int J Radiat Oncol Biol Phys 2010. PubMed
  • Smith BD, Bentzen SM, Correa CR, Hahn CA, Hardenbergh PH, Ibbott GS, McCormick B, McQueen JR, Pierce LJ, Powell SN, Recht A, Taghian AG, Vicini FA, White JR, Haffty BG. Fractionation for Whole Breast Irradiation: An American Society for Radiation Oncology (ASTRO) Evidence-Based Guideline. Int J Radiat Oncol Biol Phys 2010. PubMed
  • Adesiyun TA, Lee BT, Yueh JH, Chen C, Colakoglu S, Anderson KE, Nguyen MD, Recht A. Impact of Sequencing of Postmastectomy Radiotherapy and Breast Reconstruction on Timing and Rate of Complications and Patient Satisfaction. Int J Radiat Oncol Biol Phys 2010. PubMed
  • Varlotto JM, Recht A, Flickinger JC, Medford-Davis LN, Dyer AM, Decamp MM. Varying recurrence rates and risk factors associated with different definitions of local recurrence in patients with surgically resected, stage I nonsmall cell lung cancer. Cancer 2010; 116:2390-400. PubMed
  • Lee BT, A Adesiyun T, Colakoglu S, Curtis MS, Yueh JH, E Anderson K, Tobias AM, Recht A. Postmastectomy radiation therapy and breast reconstruction: an analysis of complications and patient satisfaction. Ann Plast Surg 2010; 64:679-83. PubMed
  • Recht A. Radiotherapy, antihormonal therapy, and personalised medicine. Lancet Oncol 2010; 11:215-6. PubMed
  • Hughes LL, Wang M, Page DL, Gray R, Solin LJ, Davidson NE, Lowen MA, Ingle JN, Recht A, Wood WC. Local excision alone without irradiation for ductal carcinoma in situ of the breast: a trial of the Eastern Cooperative Oncology Group. J Clin Oncol 2009; 27:5319-24. PubMed
  • Shields HM,Recht A,Wang HH. Exposure to Both Radiation and Chemotherapy Increases the Risk of Barrett's and Multilayered Epithelium. Dig Dis Sci 2009; 54:2143-9. PubMed
  • Silverstein MJ, Recht A, Lagios MD, Bleiweiss IJ, Blumencranz PW, Gizienski T, Harms SE, Harness J, Jackman RJ, Klimberg VS, Kuske R, Levine GM, Linver MN, Rafferty EA, Rugo H, Schilling K, Tripathy D, Vicini FA, Whitworth PW, Willey SC. Special report: Consensus conference III. Image-detected breast cancer: state-of-the-art diagnosis and treatment. J Am Coll Surg 2009; 209:504-20. PubMed
  • Recht A, Ancukiewicz M, Alm El-Din MA, Lu XQ, Martin C, Berman SM, Hirsch AE, Kachnic LA, Katz A, MacDonald S, Nedea EA, Stevenson MA, Powell SN, Taghian AG. Lung dose-volume parameters and the risk of pneumonitis for patients treated with accelerated partial-breast irradiation using three-dimensional conformal radiotherapy. J Clin Oncol 2009; 27:3887-93. PubMed
  • Varlotto JM, Flickinger JC, Recht A, Nikolov MC, DeCamp MM. A comparison of survival and disease-specific survival in surgically resected, lymph node-positive bronchioloalveolar carcinoma versus nonsmall cell lung cancer: implications for adjuvant therapy. Cancer 2008; 112:1547-54. PubMed
  • Recht A. New radiation treatment strategies for early stage breast cancer. Cancer Treat Res 2008; 141:135-48. PubMed
  • Balboni TA, Chen MH, Harris JR, Recht A, Stevenson MA, D'Amico AV. Academic career selection and retention in radiation oncology: the joint center for radiation therapy experience. Int J Radiat Oncol Biol Phys 2007; 68:183-6. PubMed
  • Alexander BM, Bryan B, Collins LC, Recht A. Atypical cytology in a persistent seroma following mastectomy for breast cancer: a case report and review of the literature. Breast J 2007; 13:196-9. PubMed
  • Recht A. The weakest link. Eur J Cancer 2006; 43:228-30. PubMed
  • Zhou P, Gautam S, Recht A. Factors affecting outcome for young women with early stage invasive breast cancer treated with breast-conserving therapy. Breast Cancer Res Treat 2006; 101:51-7. PubMed
  • Kozak KR, Smith BL, Adams J, Kornmehl E, Katz A, Gadd M, Specht M, Hughes K, Gioioso V, Lu HM, Braaten K, Recht A, Powell SN, DeLaney TF, Taghian AG. Accelerated partial-breast irradiation using proton beams: initial clinical experience. Int J Radiat Oncol Biol Phys 2006; 66:691-8. PubMed
  • Recht A. Which breast cancer patients should really worry about radiation-induced heart disease--and how much? J Clin Oncol 2006; 24:4059-61. PubMed
  • Pomahac B, Recht A, May JW, Hergrueter CA, Slavin SA. New Trends in Breast Cancer Management: Is the Era of Immediate Breast Reconstruction Changing? Ann Surg 2006; 244:282-288. PubMed
  • Lim M, Bellon JR, Gelman R, Silver B, Recht A, Schnitt SJ, Harris JR. A prospective study of conservative surgery without radiation therapy in select patients with Stage I breast cancer. Int J Radiat Oncol Biol Phys 2006; 65:1149-54. PubMed
  • Taghian AG, Kozak KR, Doppke KP, Katz A, Smith BL, Gadd M, Specht M, Hughes K, Braaten K, Kachnic LA, Recht A, Powell SN. Initial dosimetric experience using simple three-dimensional conformal external-beam accelerated partial-breast irradiation. Int J Radiat Oncol Biol Phys 2006; 64:1092-9. PubMed
  • Carlson RW, Brown E, Burstein HJ, Gradishar WJ, Hudis CA, Loprinzi C, Mamounas EP, Perez EA, Pritchard K, Ravdin P, Recht A, Somlo G, Theriault RL, Winer EP, Wolff AC,. NCCN Task Force Report: Adjuvant Therapy for Breast Cancer. J Natl Compr Canc Netw 2006; 4 Suppl 1:S1-26. PubMed
  • Bellon JR, Come SE, Gelman RS, Henderson IC, Shulman LN, Silver BJ, Harris JR, Recht A. Sequencing of chemotherapy and radiation therapy in early-stage breast cancer: updated results of a prospective randomized trial. J Clin Oncol 2005; 23:1934-40. PubMed
  • Thurman SA, Schnitt SJ, Connolly JL, Gelman R, Silver B, Harris JR, Recht A. Outcome after breast-conserving therapy for patients with stage I or II mucinous, medullary, or tubular breast carcinoma. Int J Radiat Oncol Biol Phys 2004; 59:152-9. PubMed
  • Punglia RS, Kuntz KM, Lee JH, Recht A. Radiation therapy plus tamoxifen versus tamoxifen alone after breast-conserving surgery in postmenopausal women with stage I breast cancer: a decision analysis. J Clin Oncol 2003; 21:2260-7. PubMed
  • Galper S, Gelman R, Recht A, Silver B, Kohli A, Wong JS, Van Buren T, Baldini EH, Harris JR. Second nonbreast malignancies after conservative surgery and radiation therapy for early-stage breast cancer. Int J Radiat Oncol Biol Phys 2002; 52:406-14. PubMed
  • Galper S, Recht A, Silver B, Bernardo MV, Gelman R, Wong J, Schnitt SJ, Connolly JL, Harris JR. Is radiation alone adequate treatment to the axilla for patients with limited axillary surgery? Implications for treatment after a positive sentinel node biopsy. Int J Radiat Oncol Biol Phys 2000; 48:125-32. PubMed
  • Park CC, Mitsumori M, Nixon A, Recht A, Connolly J, Gelman R, Silver B, Hetelekidis S, Abner A, Harris JR, Schnitt SJ. Outcome at 8 years after breast-conserving surgery and radiation therapy for invasive breast cancer: influence of margin status and systemic therapy on local recurrence. J Clin Oncol 2000; 18:1668-75. PubMed
  • Hetelekidis S, Schnitt SJ, Silver B, Manola J, Bornstein BA, Nixon AJ, Recht A, Gelman R, Harris JR, Connolly JL. The significance of extracapsular extension of axillary lymph node metastases in early-stage breast cancer. Int J Radiat Oncol Biol Phys 2000; 46:31-4. PubMed
  • Peiro G, Bornstein BA, Connolly JL, Gelman R, Hetelekidis S, Nixon AJ, Recht A, Silver B, Harris JR, Schnitt SJ. The influence of infiltrating lobular carcinoma on the outcome of patients treated with breast-conserving surgery and radiation therapy. Breast Cancer Res Treat 2000; 59:49-54. PubMed
  • Dubey A, Recht A, Come SE, Gelman RS, Silver B, Harris JR, Shulman LN. Concurrent CMF and radiation therapy for early stage breast cancer: results of a pilot study. Int J Radiat Oncol Biol Phys 1999; 45:877-84. PubMed
  • Abner AL, Collins L, Peiro G, Recht A, Come S, Shulman LN, Silver B, Nixon A, Harris JR, Schnitt SJ, Connolly JL. Correlation of tumor size and axillary lymph node involvement with prognosis in patients with T1 breast carcinoma. Cancer 1999; 83:2502-8. PubMed
  • Shapiro CL, Hardenbergh PH, Gelman R, Blanks D, Hauptman P, Recht A, Hayes DF, Harris J, Henderson IC. Cardiac effects of adjuvant doxorubicin and radiation therapy in breast cancer patients. J Clin Oncol 1998; 16:3493-501. PubMed
  • Chabner E, Nixon A, Gelman R, Hetelekidis S, Recht A, Bornstein B, Connolly J, Schnitt S, Silver B, Manola J, Harris J, Garber J. Family history and treatment outcome in young women after breast-conserving surgery and radiation therapy for early-stage breast cancer. J Clin Oncol 1998; 16:2045-51. PubMed
  • Gage I, Schnitt SJ, Recht A, Abner A, Come S, Shulman LN, Monson JM, Silver B, Harris JR, Connolly JL. Skin recurrences after breast-conserving therapy for early-stage breast cancer. J Clin Oncol 1998; 16:480-6. PubMed
  • Connolly JL, Boyages J, Nixon AJ, Peir. Predictors of breast recurrence after conservative surgery and radiation therapy for invasive breast cancer. Mod Pathol 1998; 11:134-9. PubMed
  • Monson JM, Chin L, Nixon A, Gage I, Silver B, Recht A, Harris JR. Is machine energy (4-8 MV) associated with outcome for stage I-II breast cancer patients? Int J Radiat Oncol Biol Phys 1997; 37:1095-100. PubMed
  • Recht A, Come SE, Henderson IC, Gelman RS, Silver B, Hayes DF, Shulman LN, Harris JR. The sequencing of chemotherapy and radiation therapy after conservative surgery for early-stage breast cancer. N Engl J Med 1996; 334:1356-61. PubMed
  • Gage I, Recht A, Gelman R, Nixon AJ, Silver B, Bornstein BA, Harris JR. Long-term outcome following breast-conserving surgery and radiation therapy. Int J Radiat Oncol Biol Phys 1995; 33:245-51. PubMed
  • Buswell L, Recht A, Clark J, Ravikumar T, Busse PM, Coleman CN. Combined-modality therapy of esophageal cancer with radiotherapy, etanidazole, and cisplatin-fluorouracil, with or without surgery: neurotoxicity, other toxicities and outcome. Int J Radiat Oncol Biol Phys 1994; 29:535-40. PubMed
  • Recht A, Come SE, Gelman RS, Goldstein M, Tishler S, Gore SM, Abner AL, Vicini FA, Silver B, Connolly JL. Integration of conservative surgery, radiotherapy, and chemotherapy for the treatment of early-stage, node-positive breast cancer: sequencing, timing, and outcome. J Clin Oncol 1991; 9:1662-7. PubMed
  • Recht A, Pierce SM, Abner A, Vicini F, Osteen RT, Love SM, Silver B, Harris JR. Regional nodal failure after conservative surgery and radiotherapy for early-stage breast carcinoma. J Clin Oncol 1991; 9:988-96. PubMed
  • Recht A, Schnitt SJ, Connolly JL, Rose MA, Silver B, Come S, Henderson IC, Slavin S, Harris JR. Prognosis following local or regional recurrence after conservative surgery and radiotherapy for early stage breast carcinoma. Int J Radiat Oncol Biol Phys 1988; 16:3-9. PubMed
  • Recht A, Silen W, Schnitt SJ, Connolly JL, Gelman RS, Rose MA, Silver B, Harris JR. Time-course of local recurrence following conservative surgery and radiotherapy for early stage breast cancer. Int J Radiat Oncol Biol Phys 1988; 15:255-61. PubMed
  • Recht A, Siddon RL, Kaplan WD, Andersen JW, Harris JR. Three-dimensional internal mammary lymphoscintigraphy: implications for radiation therapy treatment planning for breast carcinoma. Int J Radiat Oncol Biol Phys 1988; 14:477-81. PubMed
  • Recht A, Connolly JL, Schnitt SJ, Silver B, Rose MA, Love S, Harris JR. The effect of young age on tumor recurrence in the treated breast after conservative surgery and radiotherapy. Int J Radiat Oncol Biol Phys 1987; 14:3-10. PubMed
  • Recht A, Danoff BS, Solin LJ, Schnitt S, Connolly J, Botnick L, Goldberg I, Goodman RL, Harris JR. Intraductal carcinoma of the breast: results of treatment with excisional biopsy and irradiation. J Clin Oncol 1985; 3:1339-43. PubMed
  • Schnitt SJ, Connolly JL, Recht A, Silver B, Harris JR. Breast relapse following primary radiation therapy for early breast cancer. II. Detection, pathologic features and prognostic significance. Int J Radiat Oncol Biol Phys 1985; 11:1277-84. PubMed
  • Harris JR, Recht A, Amalric R, Calle R, Clark RM, Reid JG, Spitalier JM, Vilcoq JR, Hellman S. Time course and prognosis of local recurrence following primary radiation therapy for early breast cancer. J Clin Oncol 1983; 2:37-41. PubMed
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