Photo of Adam Kibel,  MD

Adam Kibel, MD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 732-6665

Adam Kibel, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Professor, Surgery, Harvard Medical School
  • Chief of Urology, Surgery/Urology, Brigham And Women's Hospital
  • Chief of Urology, Genitourinary Maligncies, Dana-Farber Cancer Institute

DF/HCC PROGRAM AFFILIATION

DF/HCC ASSOCIATIONS

  • Member, Center Scientific Council

Research Abstract

I serve as the Chief of Urology for the Brigham and Women’s Hospital as well as Chairman of the Harvard Urology Residency (Longwood). My practice encompasses complex open and minimally invasive oncology cases. A large portion of my practice is centered on robotic surgery for urologic cancers.

From a research perspective, I am interested in elucidating the molecular basis of prostate cancer aggressiveness. In collaboration with others both within and without the Harvard System, I identified multiple genetic variants associated with aggressive prostate carcinoma. At the current time, we are completing several important projects. We have performed whole genome sequencing on aggressive and indolent prostate tumors, to determine if there are driver mutations for aggressive disease. We are also performing whole exome sequencing on germline DNA to determine if rare variants are associated with risk of aggressive disease. I am particularly interested in integrating environmental determinants of risk since they offer the potential to alter the underlying genetic predisposition to disease.

In addition, I have lead efforts to integrate improved imaging into our care of patients with urologic malignancies. This includes FDG-PET in bladder cancer and C11 Acetate PET in prostate. Lastly, I’m involved in ongoing trials to integrate adjuvant and neoadjuvant systemic therapy into our management of patients with urologic malignancies.

Publications

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  • Hanske J, Sanchez A, Schmid M, Meyer CP, Abdollah F, Feldman AS, Kibel AS, Sammon JD, Menon M, Eswara JR, Noldus J, Trinh QD. A Comparison of 30-Day Perioperative Outcomes in Open Versus Minimally Invasive Nephroureterectomy for Upper Tract Urothelial Carcinoma: Analysis of 896 Patients from the American College of Surgeons-National Surgical Quality Improvement Program Database. J Endourol 2015. PubMed
  • Pandey A, Sood A, Sammon JD, Abdollah F, Gupta E, Golwala H, Bardia A, Kibel AS, Menon M, Trinh QD. Effect of Preoperative Angina Pectoris on Cardiac Outcomes in Patients With Previous Myocardial Infarction Undergoing Major Noncardiac Surgery (Data from ACS-NSQIP). Am J Cardiol 2015; 115:1080-4. PubMed
  • Meyer CP, Hanske J, Friedlander DF, Schmid M, Dahlem R, Trinh VQ, Chang SL, Kibel AS, Chun FK, Fisch M, Trinh QD, Eswara JR. The Impact of Resident Involvement in Male One-stage Anterior Urethroplasties. Urology 2015; 85:937-41. PubMed
  • Preston MA, Lerner SP, Kibel AS. New Trends in the Surgical Management of Invasive Bladder Cancer. Hematol Oncol Clin North Am 2015; 29:253-269. PubMed
  • Stegeman S, Amankwah E, Klein K, O'Mara TA, Kim D, Lin HY, Permuth-Wey J, Sellers TA, Srinivasan S, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pharoah P, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Kaneva R, Teixeira MR, , , Spurdle AB, Clements JA, Park JY, Batra J. A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer. 2015; 5:368-79. PubMed
  • Cookson MS, Lowrance WT, Murad MH, Kibel AS. Castration-resistant prostate cancer: AUA guideline amendment. J Urol 2015; 193:491-9. PubMed
  • Sammon JD, McKay RR, Kim SP, Sood A, Sukumar S, Hayn MH, Hu JC, Kibel AS, Nguyen PL, Peabody JO, Saad F, Sun M, Varda B, Menon M, Choueiri TK, Trinh QD. Burden of hospital admissions and utilization of hospice care in metastatic prostate cancer patients. Urology 2015; 85:343-9. PubMed
  • Shui IM, Lindström S, Kibel AS, Berndt SI, Campa D, Gerke T, Penney KL, Albanes D, Berg C, Bueno-de-Mesquita HB, Chanock S, Crawford ED, Diver WR, Gapstur SM, Gaziano JM, Giles GG, Henderson B, Hoover R, Johansson M, Le Marchand L, Ma J, Navarro C, Overvad K, Schumacher FR, Severi G, Siddiq A, Stampfer M, Stevens VL, Travis RC, Trichopoulos D, Vineis P, Mucci LA, Yeager M, Giovannucci E, Kraft P. Prostate cancer (PCa) risk variants and risk of fatal PCa in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. Eur Urol 2014; 65:1069-75. PubMed
  • Choueiri TK, Jacobus S, Bellmunt J, Qu A, Appleman LJ, Tretter C, Bubley GJ, Stack EC, Signoretti S, Walsh M, Steele G, Hirsch M, Sweeney CJ, Taplin ME, Kibel AS, Krajewski KM, Kantoff PW, Ross RW, Rosenberg JE. Neoadjuvant Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin With Pegfilgrastim Support in Muscle-Invasive Urothelial Cancer: Pathologic, Radiologic, and Biomarker Correlates. J Clin Oncol 2014. PubMed
  • Aizer AA, Urun Y, McKay RR, Kibel AS, Nguyen PL, Choueiri TK. Cytoreductive nephrectomy in patients with metastatic non-clear-cell renal cell carcinoma (RCC). BJU Int 2014; 113:E67-74. PubMed
  • Gandaglia G, Sammon JD, Chang SL, Choueiri TK, Hu JC, Karakiewicz PI, Kibel AS, Kim SP, Konijeti R, Montorsi F, Nguyen PL, Sukumar S, Menon M, Sun M, Trinh QD. Comparative Effectiveness of Robot-Assisted and Open Radical Prostatectomy in the Postdissemination Era. J Clin Oncol 2014. PubMed
  • Gray PJ, Lin CC, Jemal A, Shipley WU, Fedewa SA, Kibel AS, Rosenberg JE, Kamat AM, Virgo KS, Blute ML, Zietman AL, Efstathiou JA. Clinical-pathologic stage discrepancy in bladder cancer patients treated with radical cystectomy: results from the national cancer data base. Int J Radiat Oncol Biol Phys 2014; 88:1048-56. PubMed
  • Leow JJ, Reese S, Trinh QD, Bellmunt J, Chung BI, Kibel AS, Chang SL. The Impact of Surgeon Volume on the Morbidity and Costs of Radical Cystectomy in the United States: A Contemporary Population-Based Analysis. BJU Int 2014. PubMed
  • Borza T, Kibel AS. Local treatment of high risk prostate cancer: Role of surgery and radiation therapy. Cancer 2014. PubMed
  • Bhojani N, Gandaglia G, Sood A, Rai A, Pucheril D, Chang SL, Karakiewicz PI, Menon M, Olugbade K, Ruhotina N, Sammon JD, Sukumar S, Sun M, Ghani KR, Schmid M, Varda B, Kibel AS, Zorn KC, Trinh QD. Morbidity and Mortality After Benign Prostatic Hyperplasia Surgery: Data from the American College of Surgeons National Surgical Quality Improvement Program. J Endourol 2014. PubMed
  • Ahmed K, Khan SA, Hayn MH, Agarwal PK, Badani KK, Balbay MD, Castle EP, Dasgupta P, Ghavamian R, Guru KA, Hemal AK, Hollenbeck BK, Kibel AS, Menon M, Mottrie A, Nepple K, Pattaras JG, Peabody JO, Poulakis V, Pruthi RS, Redorta JP, Rha KH, Richstone L, Saar M, Scherr DS, Siemer S, Stoeckle M, Wallen EM, Weizer AZ, Wiklund P, Wilson T, Woods M, Khan MS. Analysis of intracorporeal compared with extracorporeal urinary diversion after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol 2014; 65:340-7. PubMed
  • Saunders EJ, Dadaev T, Leongamornlert DA, Jugurnauth-Little S, Tymrakiewicz M, Wiklund F, Al Olama AA, Benlloch S, Neal DE, Hamdy FC, Donovan JL, Giles GG, Severi G, Gronberg H, Aly M, Haiman CA, Schumacher F, Henderson BE, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock S, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Nordestgaard BG, Canzian F, Campa D, Riboli E, Key TJ, Travis RC, Ingles SA, John EM, Hayes RB, Pharoah P, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Clements JA, Teixeira MR, Xu J, Mikropoulos C, Goh C, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, , , , , Easton DF, Muir K, Eeles RA, Kote-Jarai Z. Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer. PLoS Genet. 2014; 10:e1004129. PubMed
  • Leow JJ, Reese SW, Jiang W, Lipsitz SR, Bellmunt J, Trinh QD, Chung BI, Kibel AS, Chang SL. Propensity-Matched Comparison of Morbidity and Costs of Open and Robot-Assisted Radical Cystectomies: A Contemporary Population-Based Analysis in the United States. Eur Urol 2014. PubMed
  • Antczak C, Trinh VQ, Sood A, Ravi P, Roghmann F, Trudeau V, Chang SL, Karakiewicz PI, Kibel AS, Krishna N, Nguyen PL, Saad F, Sammon JD, Sukumar S, Zorn KC, Sun M, Trinh QD. The health care burden of skeletal-related events in renal cell carcinoma patients with bone metastases. J Urol 2014. PubMed
  • Mir MC, Stephenson AJ, Grubb RL, Black A, Kibel AS, Izmirlian G. Predicting risk of bladder cancer using clinical and demographic information from prostate, lung, colorectal, and ovarian cancer screening trial participants. Cancer Epidemiol Biomarkers Prev 2013; 22:2241-9. PubMed
  • Borza T, Konijeti R, Kibel AS. Early detection, PSA screening, and management of overdiagnosis. Hematol Oncol Clin North Am 2013; 27:1091-110, vii. PubMed
  • Al-Daghmin A, Kauffman EC, Shi Y, Badani K, Balbay MD, Canda E, Dasgupta P, Ghavamian R, Grubb R, Hemal A, Kaouk J, Kibel AS, Maatman T, Menon M, Mottrie A, Nepple K, Pattaras JG, Peabody JO, Poulakis V, Pruthi R, Redorta JP, Rha KH, Richstone L, Schanne F, Scherr DS, Siemer S, Stöckle M, Wallen EM, Weizer A, Wiklund P, Wilson T, Wilding G, Woods M, Guru KA. Efficacy of Robot-assisted Radical Cystectomy in Advanced Bladder Cancer: Results from the International Radical Cystectomy Consortium (IRCC). BJU Int 2013. PubMed
  • Schweizer MT, Huang P, Kattan MW, Kibel AS, de Wit R, Sternberg CN, Epstein JI, Eisenberger MA. Adjuvant leuprolide with or without docetaxel in patients with high-risk prostate cancer after radical prostatectomy (TAX-3501): important lessons for future trials. Cancer 2013; 119:3610-8. PubMed
  • Lin C, Yin Y, Stemler K, Humphrey P, Kibel AS, Mysorekar IU, Ma L. Constitutive 硫-catenin activation induces male-specific tumorigenesis in the bladder urothelium. Cancer Res 2013; 73:5914-25. PubMed
  • Kacker R, Kibel AS. Re: Intermittent Androgen Suppression for Rising PSA Level After Radiotherapy. Eur Urol 2013; 63:1129-30. PubMed
  • Cookson MS, Roth BJ, Dahm P, Engstrom C, Freedland SJ, Hussain M, Lin DW, Lowrance WT, Murad MH, Oh WK, Penson DF, Kibel AS. Castration-Resistant Prostate Cancer: AUA Guideline. J Urol 2013. PubMed
  • Kibel AS. Response to Letter to the Editor. J Urol 2013. PubMed
  • Patterson RE, Colditz GA, Hu FB, Schmitz KH, Ahima RS, Brownson RC, Carson KR, Chavarro JE, Chodosh LA, Gehlert S, Gill J, Glanz K, Haire-Joshu D, Herbst KL, Hoehner CM, Hovmand PS, Irwin ML, Jacobs LA, James AS, Jones LW, Kerr J, Kibel AS, King IB, Ligibel JA, Meyerhardt JA, Natarajan L, Neuhouser ML, Olefsky JM, Proctor EK, Redline S, Rock CL, Rosner B, Sarwer DB, Schwartz JS, Sears DD, Sesso HD, Stampfer MJ, Subramanian SV, Taveras EM, Tchou J, Thompson B, Troxel AB, Wessling-Resnick M, Wolin KY, Thornquist MD. The 2011-2016 Transdisciplinary Research on Energetics and Cancer (TREC) initiative: rationale and design. Cancer Causes Control 2013; 24:695-704. PubMed
  • Eeles RA, Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock SJ, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah PD, Pashayan N, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A, Dunning AM, Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL, English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R, Diver WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors T, Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, Røder MA, Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM, Karyadi DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake B, Colditz G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Sellers TA, Lin HY, Slavov C, Mitev V, Lose F, Srinivasan S, Maia S, Paulo P, Lange E, Cooney KA, Antoniou AC, Vincent D, Bacot F, Tessier DC, , , , , , Kote-Jarai Z, Easton DF. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet 2013; 45:385-91. PubMed
  • Kote-Jarai Z, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Dadaev T, Jugurnauth-Little S, Ross-Adams H, Al Olama AA, Benlloch S, Halim S, Russel R, Dunning AM, Luccarini C, Dennis J, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Marchand LL, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock S, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah P, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle A, Clements JA, Teixeira MR, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dicks E, Baynes C, Conroy D, Bojesen SE, Kaaks R, Vincent D, Bacot F, Tessier DC, , , , , Easton DF, Eeles RA. Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression. Hum Mol Genet 2013. PubMed
  • Nepple KG, Stephenson AJ, Kallogjeri D, Michalski J, Grubb RL, Strope SA, Haslag-Minoff J, Piccirillo JF, Ciezki JP, Klein EA, Reddy CA, Yu C, Kattan MW, Kibel AS. Mortality After Prostate Cancer Treatment with Radical Prostatectomy, External-Beam Radiation Therapy, or Brachytherapy in Men Without Comorbidity. Eur Urol 2013. PubMed
  • Haseebuddin M, Dehdashti F, Siegel BA, Liu J, Roth EB, Nepple KG, Siegel CL, Fischer KC, Kibel AS, Andriole GL, Miller TR. 11C-Acetate PET/CT Before Radical Prostatectomy: Nodal Staging and Treatment Failure Prediction. J Nucl Med 2013. PubMed
  • Kibel AS. Editorial comment. J Urol 2013; 189:853. PubMed
  • Marshall SJ, Hayn MH, Stegemann AP, Agarwal PK, Badani KK, Balbay MD, Dasgupta P, Hemal AK, Hollenbeck BK, Kibel AS, Menon M, Mottrie A, Nepple K, Pattaras JG, Peabody JO, Poulakis V, Pruthi RS, Palou Redorta J, Rha KH, Richstone L, Schanne F, Scherr DS, Siemer S, Stöckle M, Wallen EM, Weizer AZ, Wiklund P, Wilson T, Woods M, Guru KA. Impact of surgeon and volume on extended lymphadenectomy at the time of robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium (IRCC). BJU Int 2013. PubMed
  • Ukimura O, Coleman JA, de la Taille A, Emberton M, Epstein JI, Freedland SJ, Giannarini G, Kibel AS, Montironi R, Ploussard G, Roobol MJ, Scattoni V, Jones JS. Contemporary role of systematic prostate biopsies: indications, techniques, and implications for patient care. Eur Urol 2012; 63:214-30. PubMed
  • Johar RS, Hayn MH, Stegemann AP, Ahmed K, Agarwal P, Balbay MD, Hemal A, Kibel AS, Muhletaler F, Nepple K, Pattaras JG, Peabody JO, Palou Redorta J, Rha KH, Richstone L, Saar M, Schanne F, Scherr DS, Siemer S, Stökle M, Weizer A, Wiklund P, Wilson T, Woods M, Yuh B, Guru KA. Complications After Robot-assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium. Eur Urol 2013. PubMed
  • Vickers AJ, Bennette C, Kibel AS, Black A, Izmirlian G, Stephenson AJ, Bochner B. Who should be included in a clinical trial of screening for bladder cancer?: A decision analysis of data from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Cancer 2012; 119:143-9. PubMed
  • Rebbeck TR, Devesa SS, Chang BL, Bunker CH, Cheng I, Cooney K, Eeles R, Fernandez P, Giri VN, Gueye SM, Haiman CA, Henderson BE, Heyns CF, Hu JJ, Ingles SA, Isaacs W, Jalloh M, John EM, Kibel AS, Kidd LR, Layne P, Leach RJ, Neslund-Dudas C, Okobia MN, Ostrander EA, Park JY, Patrick AL, Phelan CM, Ragin C, Roberts RA, Rybicki BA, Stanford JL, Strom S, Thompson IM, Witte J, Xu J, Yeboah E, Hsing AW, Zeigler-Johnson CM. Global patterns of prostate cancer incidence, aggressiveness, and mortality in men of african descent. Prostate Cancer 2013; 2013:560857. PubMed
  • Kibel AS. To Biopsy or Not to Biopsy: Minimizing the Risk of Prostate Needle Biopsy. J Urol 2012. PubMed
  • Kibel AS. Urologic Clinics of North America. Castrate-resistant prostate cancer. Preface. Urol Clin North Am 2012; 39:xv. PubMed
  • Johnson MH, Nepple KG, Peck V, Trinkaus K, Klim A, Sandhu GS, Kibel AS. Randomized Controlled Trial of Oxybutynin Extended Release versus Placebo for Urinary Symptoms during Intravesical Bacillus Calmette-Gu辿rin Treatment. J Urol 2012. PubMed
  • Hudson J, Cao D, Vollmer R, Kibel AS, Grewal S, Humphrey PA. Foamy gland adenocarcinoma of the prostate: incidence, Gleason grade, and early clinical outcome. Hum Pathol 2012; 43:974-9. PubMed
  • Konijeti R, Kibel AS. Androgen deprivation therapy for localized and nonmetastatic prostate cancer: too much of a good thing? Eur Urol 2012; 61:1129-30; discussion 1131. PubMed
  • Yu HY, Hevelone ND, Lipsitz SR, Kowalczyk KJ, Nguyen PL, Choueiri TK, Kibel AS, Hu JC. Comparative Analysis of Outcomes and Costs Following Open Radical Cystectomy Versus Robot-Assisted Laparoscopic Radical Cystectomy: Results From the US Nationwide Inpatient Sample. Eur Urol 2012; 61:1239-44. PubMed
  • Kibel AS, Ciezki JP, Klein EA, Reddy CA, Lubahn JD, Haslag-Minoff J, Deasy JO, Michalski JM, Kallogjeri D, Piccirillo JF, Rabah DM, Yu C, Kattan MW, Stephenson AJ. Survival among men with clinically localized prostate cancer treated with radical prostatectomy or radiation therapy in the prostate specific antigen era. J Urol 2012; 187:1259-65. PubMed
  • Kibel AS. Treat now or later: the dilemma of postoperative radiotherapy. Eur Urol 2012; 61:452-4. PubMed
  • Gardner MW, Roytman TM, Chen C, Brandes SB, Kibel AS, Grubb RL, Bhayani SB, Figenshau RS. Laparoscopic retroperitoneal lymph node dissection for low-stage cancer: a Washington University update. J Endourol 2011; 25:1753-7. PubMed
  • Alemozaffar M, Regan MM, Cooperberg MR, Wei JT, Michalski JM, Sandler HM, Hembroff L, Sadetsky N, Saigal CS, Litwin MS, Klein E, Kibel AS, Hamstra DA, Pisters LL, Kuban DA, Kaplan ID, Wood DP, Ciezki J, Dunn RL, Carroll PR, Sanda MG. Prediction of erectile function following treatment for prostate cancer. JAMA 2011; 306:1205-14. PubMed
  • Nepple KG, Strope SA, Grubb RL, Kibel AS. Early oncologic outcomes of robotic vs. open radical cystectomy for urothelial cancer. Urol Oncol 2011. PubMed
  • Haiman CA, Chen GK, Blot WJ, Strom SS, Berndt SI, Kittles RA, Rybicki BA, Isaacs WB, Ingles SA, Stanford JL, Diver WR, Witte JS, Hsing AW, Nemesure B, Rebbeck TR, Cooney KA, Xu J, Kibel AS, Hu JJ, John EM, Gueye SM, Watya S, Signorello LB, Hayes RB, Wang Z, Yeboah E, Tettey Y, Cai Q, Kolb S, Ostrander EA, Zeigler-Johnson C, Yamamura Y, Neslund-Dudas C, Haslag-Minoff J, Wu W, Thomas V, Allen GO, Murphy A, Chang BL, Zheng SL, Leske MC, Wu SY, Ray AM, Hennis AJ, Thun MJ, Carpten J, Casey G, Carter EN, Duarte ER, Xia LY, Sheng X, Wan P, Pooler LC, Cheng I, Monroe KR, Schumacher F, Le Marchand L, Kolonel LN, Chanock SJ, Van Den Berg D, Stram DO, Henderson BE. Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet 2011; 43:570-3. PubMed
  • Cao D, Humphrey PA, Gao F, Tao Y, Kibel AS. Ability of linear length of positive margin in radical prostatectomy specimens to predict biochemical recurrence. Urology 2011; 77:1409-14. PubMed
  • Sundaram V, Figenshau RS, Roytman TM, Kibel AS, Grubb RL, Bullock A, Benway BM, Bhayani SB. Positive margin during partial nephrectomy: does cancer remain in the renal remnant? Urology 2011; 77:1400-3. PubMed
  • Nepple KG, Kibel AS. Words of wisdom. Re: active surveillance compared with initial treatment for men with low-risk prostate cancer: a decision analysis. Eur Urol 2011; 59:883-4. PubMed
  • Andriole GL, Kibel AS. Editorial for "Prediction of significant prostate cancer diagnosed 20 to 30 years later with a single measure of prostate-specific antigen at or before age 50". Cancer 2011; 117:1110-2. PubMed
  • Ahn J, Kibel AS, Park JY, Rebbeck TR, Rennert H, Stanford JL, Ostrander EA, Chanock S, Wang MH, Mittal RD, Isaacs WB, Platz EA, Hayes RB. Prostate cancer predisposition loci and risk of metastatic disease and prostate cancer recurrence. Clin Cancer Res 2011; 17:1075-81. PubMed
  • Chang BL, Spangler E, Gallagher S, Haiman CA, Henderson B, Isaacs W, Benford ML, Kidd LR, Cooney K, Strom S, Ingles SA, Stern MC, Corral R, Joshi AD, Xu J, Giri VN, Rybicki B, Neslund-Dudas C, Kibel AS, Thompson IM, Leach RJ, Ostrander EA, Stanford JL, Witte J, Casey G, Eeles R, Hsing AW, Chanock S, Hu JJ, John EM, Park J, Stefflova K, Zeigler-Johnson C, Rebbeck TR. Validation of genome-wide prostate cancer associations in men of African descent. Cancer Epidemiol Biomarkers Prev 2011; 20:23-32. PubMed
  • Cao D, Kibel AS, Gao F, Tao Y, Humphrey PA. The Gleason score of tumor at the margin in radical prostatectomy is predictive of biochemical recurrence. Am J Surg Pathol 2010; 34:994-1001. PubMed
  • Lubahn J, Berndt SI, Jin CH, Klim A, Luly J, Wu WS, Isaacs S, Wiley K, Isaacs WB, Suarez BK, Hayes RB, Kibel AS. Association of CASP8 D302H polymorphism with reduced risk of aggressive prostate carcinoma. Prostate 2010; 70:646-53. PubMed
  • Grubb RL, Kibel AS. High-risk localized prostate cancer: role of radical prostatectomy. Curr Opin Urol 2010; 20:204-10. PubMed
  • Katz MD, Serrano MF, Grubb RL, Skolarus TA, Gao F, Humphrey PA, Kibel AS. Percent microscopic tumor necrosis and survival after curative surgery for renal cell carcinoma. J Urol 2010; 183:909-14. PubMed
  • Skolarus TA, Serrano MF, Grubb RL, Katz MD, Bullock TL, Gao F, Humphrey PA, Kibel AS. Effect of reclassification on the incidence of benign and malignant renal tumors. J Urol 2010; 183:455-8. PubMed
  • Wolin KY, Luly J, Sutcliffe S, Andriole GL, Kibel AS. Risk of urinary incontinence following prostatectomy: the role of physical activity and obesity. J Urol 2010; 183:629-33. PubMed
  • Shteynshlyuger A, Kibel AS. Words of wisdom. Re: Prostate cancer-specific mortality after radical prostatectomy for patients treated in the prostate-specific antigen era. Eur Urol 2010; 56:1089-90. PubMed
  • Kibel AS, Dehdashti F, Katz MD, Klim AP, Grubb RL, Humphrey PA, Siegel C, Cao D, Gao F, Siegel BA. Prospective study of [18F]fluorodeoxyglucose positron emission tomography/computed tomography for staging of muscle-invasive bladder carcinoma. J Clin Oncol 2009; 27:4314-20. PubMed
  • Skolarus TA, Lee EW, Virgo KS, Katz MD, Hudson MA, Kibel AS, Grubb RL. Intravesical bacille Calmette-Gu辿rin therapy for non-muscle-invasive bladder cancer: effects of concurrent statin therapy. J Am Coll Surg 2009; 209:248-53. PubMed
  • Xu J, Kibel AS, Hu JJ, Turner AR, Pruett K, Zheng SL, Sun J, Isaacs SD, Wiley KE, Kim ST, Hsu FC, Wu W, Torti FM, Walsh PC, Chang BL, Isaacs WB. Prostate cancer risk associated loci in African Americans. Cancer Epidemiol Biomarkers Prev 2009; 18:2145-9. PubMed
  • Ahn J, Albanes D, Berndt SI, Peters U, Chatterjee N, Freedman ND, Abnet CC, Huang WY, Kibel AS, Crawford ED, Weinstein SJ, Chanock SJ, Schatzkin A, Hayes RB, . Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk. Carcinogenesis 2009; 30:769-76. PubMed
  • Xu J, Humphrey PA, Kibel AS, Snyder AZ, Narra VR, Ackerman JJ, Song SK. Magnetic resonance diffusion characteristics of histologically defined prostate cancer in humans. Magn Reson Med 2009; 61:842-50. PubMed
  • Ahn J,Berndt SI,Wacholder S,Kraft P,Kibel AS,Yeager M,Albanes D,Giovannucci E,Stampfer MJ,Virtamo J,Thun MJ,Feigelson HS,Cancel-Tassin G,Cussenot O,Thomas G,Hunter DJ,Fraumeni JF Jr,Hoover RN,Chanock SJ,Hayes RB. Variation in KLK genes, prostate-specific antigen and risk of prostate cancer. Nat Genet 2009; 40:1032-4; author reply 1035-6. PubMed
  • Megwalu II, Ferguson GG, Wei JT, Mouraviev V, Polascik TJ, Taneja S, Black L, Andriole GL, Kibel AS. Evaluation of a novel precision template-guided biopsy system for detecting prostate cancer. BJU Int 2008; 102:546-50. PubMed
  • Berger DA, Megwalu II, Vlahiotis A, Radwan MH, Serrano MF, Humphrey PA, Piccirillo JF, Kibel AS. Impact of comorbidity on overall survival in patients surgically treated for renal cell carcinoma. Urology 2008; 72:359-63. PubMed
  • Kibel AS, Jin CH, Klim A, Luly J, A Roehl K, Wu WS, Suarez BK. Association between polymorphisms in cell cycle genes and advanced prostate carcinoma. Prostate 2008; 68:1179-86. PubMed
  • Serrano MF, Katz M, Yan Y, Kibel AS, Humphrey PA. Percentage of high-grade carcinoma as a prognostic indicator in patients with renal cell carcinoma. Cancer 2008; 113:477-83. PubMed
  • Megwalu II, Vlahiotis A, Radwan M, Piccirillo JF, Kibel AS. Prognostic impact of comorbidity in patients with bladder cancer. Eur Urol 2008; 53:581-9. PubMed
  • Skolarus TA, Serrano MF, Berger DA, Bullock TL, Yan Y, Humphrey PA, Kibel AS. The distribution of histological subtypes of renal tumors by decade of life using the 2004 WHO classification. J Urol 2008; 179:439-43; discussion 443-4. PubMed
  • Katz MD, Kibel AS. Words of wisdom. Re: EPCA-2: a highly specific serum marker for prostate cancer. Eur Urol 2008; 53:210. PubMed
  • Ogan K, Kawai K, Gill IS, Naito S, Isaacs WB, Suzuki K, Kibel AS, Kakehi Y, Yoshimura N, Yokoyama O, Chancellor MB, Takahashi S. The Second Joint Meeting of American Urological Association (AUA)/Japanese Urological Association (JUA) International Program on the 102nd Annual Meeting of American Urological Association at Anaheim 2007. Int J Urol 2007; 14:1116-23. PubMed
  • Radwan MH, Yan Y, Luly JR, Figenshau RS, Brandes SB, Bhayani SB, Bullock AD, Liefu Y, Andriole GL, Kibel AS. Prostate-specific antigen density predicts adverse pathology and increased risk of biochemical failure. Urology 2007; 69:1121-7. PubMed
  • Kibel AS, Rosenbaum E, Kattan MW, Picus J, Dreicer R, Klein EA, Chatta GS, Nelson JB, DiPaola RS, Roth BJ, Cookson MS, Wilding G, Jarrard DF, Beer TM, Ryan CW, Petrylak DP, Benson MC, Partin AW, Garrett-Mayer E, Eisenberger MA. Adjuvant weekly docetaxel for patients with high risk prostate cancer after radical prostatectomy: a multi-institutional pilot study. J Urol 2007; 177:1777-81. PubMed
  • Bhayani SB, Belani JS, Hidalgo J, Figenshau RS, Landman J, Venkatesh R, Kibel AS. Trends in nephron-sparing surgery for renal neoplasia. Urology 2006; 68:732-6. PubMed
  • Grubb RL, Vardi IY, Bhayani SB, Kibel AS. Minimally invasive approaches to localized prostate carcinoma. Hematol Oncol Clin North Am 2006; 20:879-95. PubMed
  • Noonan-Wheeler FC, Wu W, Roehl KA, Klim A, Haugen J, Suarez BK, Kibel AS. Association of hereditary prostate cancer gene polymorphic variants with sporadic aggressive prostate carcinoma. Prostate 2005; 66:49-56. PubMed
  • Belani JS, Farooki A, Prasad S, Yan Y, Heiken JP, Kibel AS. Parenchymal imaging adds diagnostic utility in evaluating haematuria. BJU Int 2005; 95:64-7. PubMed
  • Kibel AS, Huagen J, Guo C, Isaacs WB, Yan Y, Pienta KJ, Goodfellow PJ. Expression mapping at 12p12-13 in advanced prostate carcinoma. Int J Cancer 2004; 109:668-72. PubMed
  • Grubb RL, Collyer WC, Kibel AS. Transitional cell carcinoma of the renal pelvis associated with hypercalcemia in a patient with autosomal dominant polycystic kidney disease. Urology 2004; 63:778-80. PubMed
  • Bhayani SB, Clayman RV, Sundaram CP, Landman J, Andriole G, Figenshau RS, Bullock A, Brandes S, Shalhav A, McDougall E, Kibel AS. Surgical treatment of renal neoplasia: evolving toward a laparoscopic standard of care. Urology 2003; 62:821-6. PubMed
  • Kibel AS, Faith DA, Bova GS, Isaacs WB. Xq27-28 deletions in prostate carcinoma. Genes Chromosomes Cancer 2003; 37:381-8. PubMed
  • Kibel AS, Suarez BK, Belani J, Oh J, Webster R, Brophy-Ebbers M, Guo C, Catalona WJ, Picus J, Goodfellow PJ. CDKN1A and CDKN1B polymorphisms and risk of advanced prostate carcinoma. Cancer Res 2003; 63:2033-6. PubMed
  • Oyama N, Miller TR, Dehdashti F, Siegel BA, Fischer KC, Michalski JM, Kibel AS, Andriole GL, Picus J, Welch MJ. 11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse. J Nucl Med 2003; 44:549-55. PubMed
  • Yan Y, Andriole GL, Humphrey PA, Kibel AS. Patterns of multiple recurrences of superficial (Ta/T1) transitional cell carcinoma of bladder and effects of clinicopathologic and biochemical factors. Cancer 2002; 95:1239-46. PubMed
  • Kibel AS, Faith DA, Bova GS, Isaacs WB. Mutational analysis of ETV6 in prostate carcinoma. Prostate 2002; 52:305-10. PubMed
  • Landman J, Lev RY, Bhayani S, Alberts G, Rehman J, Pattaras JG, Figenshau RS, Kibel AS, Clayman RV, McDougall E. Comparison of hand assisted and standard laparoscopic radical nephroureterectomy for the management of localized transitional cell carcinoma. J Urol 2002; 167:2387-91. PubMed
  • Venkatesh R, Kibel AS, Lee D, Rehman J, Landman J. Rapid resolution of carbon dioxide pneumothorax (capno-thorax) resulting from diaphragmatic injury during laparoscopic nephrectomy. J Urol 2002; 167:1387-8. PubMed
  • Oh J, Landman J, Evers A, Yan Y, Kibel AS. Management of the postpubertal patient with cryptorchidism: an updated analysis. J Urol 2002; 167:1329-33. PubMed
  • Kibel AS. Single nucleotide polymorphisms: early diagnosis and risk assessment in genitourinary malignancy. Urol Oncol 2006; 24:224-30. PubMed
  • Shteynshlyuger A, Kibel AS. Counterpoint: Prostate carcinoma treatment for the young patient--The case for radical prostatectomy. Brachytherapy 2010; 9:195-8; discussion 199-201. PubMed
  • Lerner SP, Grossman HB, Messing EM, Kibel AS, Stephenson A, Gee JR, O'Donnell MA, Reid RD, Kamat AM, Parnes HL, House MG. BCAN Think Tank session 3: Prevention of bladder cancer. Urol Oncol 2010; 28:338-42. PubMed
  • Katz MD, Serrano MF, Humphrey PA, Grubb RL, Skolarus TA, Gao F, Kibel AS. The role of lymphovascular space invasion in renal cell carcinoma as a prognostic marker of survival after curative resection. Urol Oncol 2011; 29:738-44. PubMed
  • Lerner SP, Bochner B, Kibel AS. The use and abuse of data: nomograms and talking to patients about clinical medicine. Urol Oncol 2007; 25:333-7. PubMed
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