Photo of Alex B. Haynes,  MD, MPH

Alex B. Haynes, MD, MPH

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 643-9474
Fax: (617) 724-3895

Alex B. Haynes, MD, MPH

Massachusetts General Hospital


  • Associate Professor, Surgery, Harvard Medical School
  • Assistant in Surgery, Surgery, Massachusetts General Hospital
  • Associate Program Director for Safe Surgery, Ariadne Labs, Harvard T.H. Chan School Of Public Health


Research Abstract

My primary research interests focus on health care delivery and the identification of methods to improve uptake of clinical innovation. My focus has largely been on patient safety in surgical care, understanding that improving the quality of surgical care is essential to providing high quality cancer care. I also am active in clinical protocols assessing the outcomes of care for melanoma and cutaneous squamous cell carcinoma.

My clinical interests are in melanoma and soft tissue sarcoma, including retroperitoneal sarcoma and gastrointestinal stromal tumors. I am actively involved with the multidisciplinary tumor boards for both melanoma and connective tissue oncology at the Massachusetts General Hospital.

I teach surgical residents and surgical oncology fellows in both clinical and didactic settings. I also have two research fellows working with me at Ariadne Labs, where I hold a joint appointment.


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  • Solsky I, Haynes AB. Ten Years and Counting: Sustaining Effectiveness of the Surgical Safety Checklist Through Ongoing Implementation Efforts. World J Surg 2018. PubMed
  • Cote GM, Barysauskas CM, DeLaney T, Schwab J, Raskin K, Lozano-Calderon S, Bernstein K, Mullen J, Haynes AB, Hornicek F, Chen YL, Choy E. A Phase I Study of Nilotinib plus Radiation in High-Risk Chordoma. Int J Radiat Oncol Biol Phys 2018. PubMed
  • Kasumova GG, Haynes AB, Boland GM. Lymphatic versus Hematogenous Melanoma Metastases: Support for Biological Heterogeneity without Clear Clinical Application. J Invest Dermatol 2017; 137:2466-2468. PubMed
  • Hull MA, Molina G, Niemierko A, Haynes AB, Jacobson A, Bernstein KA, Chen YL, DeLaney TF, Mullen JT. Improved local control with an aggressive strategy of preoperative (with or without intraoperative) radiation therapy combined with radical surgical resection for retroperitoneal sarcoma. J Surg Oncol 2017. PubMed
  • Loehrer AP, Song Z, Haynes AB, Chang DC, Hutter MM, Mullen JT. Impact of Health Insurance Expansion on the Treatment of Colorectal Cancer. J Clin Oncol 2016; 34:4110-4115. PubMed
  • Molina G, Hull MA, Chen YL, DeLaney TF, De Amorim Bernstein K, Choy E, Cote G, Harmon DC, Mullen JT, Haynes AB. Preoperative radiation therapy combined with radical surgical resection is associated with a lower rate of local recurrence when treating unifocal, primary retroperitoneal liposarcoma. J Surg Oncol 2016. PubMed
  • Ahmad R, Jacobson A, Hornicek F, Haynes AB, Choy E, Cote G, Nielsen GP, Chen YL, DeLaney TF, Mullen JT. The Width of the Surgical Margin Does Not Influence Outcomes in Extremity and Truncal Soft Tissue Sarcoma Treated With Radiotherapy. Oncologist 2016. PubMed
  • Youn B, Soley-Bori M, Soria-Saucedo R, Ryan CM, Schneider JC, Haynes AB, Cabral HJ, Kazis LE. Patient cost-sharing and insurance arrangements are associated with hospital readmissions after abdominal surgery: Implications for access and quality health care. Surgery 2015. PubMed
  • Cauley CE, Panizales MT, Reznor G, Haynes AB, Havens JM, Kelley E, Mosenthal AC, Cooper Z. Outcomes after emergency abdominal surgery in patients with advanced cancer: Opportunities to reduce complications and improve palliative care. J Trauma Acute Care Surg 2015; 79:399-406. PubMed
  • Massarweh NN, Haynes AB, Chiang YJ, Chang GJ, You YN, Feig BW, Cormier JN. Adequacy of the National Quality Forum's Colon Cancer Adjuvant Chemotherapy Quality Metric: Is 4 Months Soon Enough? Ann Surg 2015. PubMed
  • Soley-Bori M, Soria-Saucedo R, Ryan CM, Schneider JC, Haynes AB, Gerrard P, Cabral HJ, Lillemoe KD, Kazis LE. Functional Status and Hospital Readmissions Using the Medical Expenditure Panel Survey. J Gen Intern Med 2015. PubMed
  • Hull MA, Niemierko A, Haynes AB, Jacobson A, Chen YL, DeLaney TF, Mullen JT. Post-operative renal function following nephrectomy as part of en bloc resection of retroperitoneal sarcoma (RPS). J Surg Oncol 2015; 112:98-102. PubMed
  • Kim RY, Kwakye G, Kwok AC, Baltaga R, Ciobanu G, Merry AF, Funk LM, Lipsitz SR, Gawande AA, Berry WR, Haynes AB. Sustainability and long-term effectiveness of the WHO surgical safety checklist combined with pulse oximetry in a resource-limited setting: two-year update from Moldova. JAMA Surg 2015. PubMed
  • Haynes AB, Berry WR, Gawande AA. What do we know about the safe surgery checklist now? Ann Surg 2015; 261:829-30. PubMed
  • Cauley CE, Haynes AB. Beyond "a chance to cut is a chance to cure": surgical quality in the cancer care continuum. Ann Surg 2015; 261:637-8. PubMed
  • Gfrerer L, Mattos D, Mastroianni M, Weng QY, Ricci JA, Heath MP, Lin A, Specht MC, Haynes AB, Austen WG, Liao EC. Assessment of patient factors, surgeons, and surgeon teams in immediate implant-based breast reconstruction outcomes. Plast Reconstr Surg 2015; 135:245e-52e. PubMed
  • Haynes AB, Bloom ES, Bedrosian I, Kuerer HM, Hwang RF, Munsell MF, Chemaly RF, Graviss LS, Caudle AS, Hunt KK, Tereffe W, Shaitelman SF, Babiera GV. Timing of infectious complications following breast-conserving therapy with catheter-based accelerated partial breast irradiation. Ann Surg Oncol 2014; 21:2512-6. PubMed
  • Haynes AB, You YN, Hu CY, Eng C, Kopetz ES, Rodriguez-Bigas MA, Skibber JM, Cantor SB, Chang GJ. Postoperative chemotherapy use after neoadjuvant chemoradiotherapy for rectal cancer: Analysis of Surveillance, Epidemiology, and End Results-Medicare data, 1998-2007. Cancer 2014; 120:1162-70. PubMed
  • Massarweh NN, Chiang YJ, Xing Y, Chang GJ, Haynes AB, You YN, Feig BW, Cormier JN. Association between travel distance and metastatic disease at diagnosis among patients with colon cancer. J Clin Oncol 2014; 32:942-8. PubMed
  • Haynes AB, Pollock RE. Lumping, splitting, and making sense: implications of soft tissue sarcoma staging for prognosis, therapy, and research. Ann Surg Oncol 2013; 20:3355-6. PubMed
  • Boland GM, Chang GJ, Haynes AB, Chiang YJ, Chagpar R, Xing Y, Hu CY, Feig BW, You YN, Cormier JN. Association between adherence to National Comprehensive Cancer Network treatment guidelines and improved survival in patients with colon cancer. Cancer 2013; 119:1593-601. PubMed
  • Weiser TG, Semel ME, Simon AE, Lipsitz SR, Haynes AB, Funk LM, Berry WR, Gawande AA. In-hospital death following inpatient surgical procedures in the United States, 1996-2006. World J Surg 2011; 35:1950-6. PubMed
  • Haynes AB, Deshpande V, Ingkakul T, Vagefi PA, Szymonifka J, Thayer SP, Ferrone CR, Wargo JA, Warshaw AL, Fernández-del Castillo C. Implications of incidentally discovered, nonfunctioning pancreatic endocrine tumors: short-term and long-term patient outcomes. Arch Surg 2011; 146:534-8. PubMed
  • Haynes AB, Regenbogen SE, Weiser TG, Lipsitz SR, Dziekan G, Berry WR, Gawande AA. Surgical outcome measurement for a global patient population: validation of the Surgical Apgar Score in 8 countries. Surgery 2011; 149:519-24. PubMed
  • Haynes AB, Weiser TG, Berry WR, Lipsitz SR, Breizat AH, Dellinger EP, Dziekan G, Herbosa T, Kibatala PL, Lapitan MC, Merry AF, Reznick RK, Taylor B, Vats A, Gawande AA, . Changes in safety attitude and relationship to decreased postoperative morbidity and mortality following implementation of a checklist-based surgical safety intervention. BMJ Qual Saf 2011; 20:102-7. PubMed
  • Weiser TG, Haynes AB, Lashoher A, Dziekan G, Boorman DJ, Berry WR, Gawande AA. Perspectives in quality: designing the WHO Surgical Safety Checklist. Int J Qual Health Care 2010; 22:365-70. PubMed
  • Semel ME, Resch S, Haynes AB, Funk LM, Bader A, Berry WR, Weiser TG, Gawande AA. Adopting a surgical safety checklist could save money and improve the quality of care in U.S. hospitals. Health Aff (Millwood) 2010; 29:1593-9. PubMed
  • Weiser TG, Haynes AB, Dziekan G, Berry WR, Lipsitz SR, Gawande AA, . Effect of a 19-item surgical safety checklist during urgent operations in a global patient population. Ann Surg 2010; 251:976-80. PubMed
  • Weiser TG, Makary MA, Haynes AB, Dziekan G, Berry WR, Gawande AA, . Standardised metrics for global surgical surveillance. Lancet 2009; 374:1113-7. PubMed
  • Haynes AB, Weiser TG, Berry WR, Lipsitz SR, Breizat AH, Dellinger EP, Herbosa T, Joseph S, Kibatala PL, Lapitan MC, Merry AF, Moorthy K, Reznick RK, Taylor B, Gawande AA, . A surgical safety checklist to reduce morbidity and mortality in a global population. N Engl J Med 2009; 360:491-9. PubMed
  • Weiser TG, Regenbogen SE, Thompson KD, Haynes AB, Lipsitz SR, Berry WR, Gawande AA. An estimation of the global volume of surgery: a modelling strategy based on available data. Lancet 2008; 372:139-44. PubMed
  • Yoon SS, Aloia TA, Haynes AB, Kambadakone A, Kaur H, Vauthey JN, Ferrone CR, Zhu AX, Wo JY, Crane C, Hong TS. Surgical placement of biologic mesh spacers to displace bowel away from unresectable liver tumors followed by delivery of dose-intense radiation therapy. 2014; 4:167-73. PubMed