Photo of Annekathryn Goodman,  MD

Annekathryn Goodman, MD

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 724-4800
Fax: (617) 724-6898

Annekathryn Goodman, MD

Massachusetts General Hospital


  • Associate Professor, Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School
  • Assistant Director, Vincent Gynecologic Oncology Division, Massachusetts General Hospital


Research Abstract

HIV and cervical neoplasia

Novel surgeries in cervical cancer

Preservation of reproductive potential

Principal Investigator Gynecology Oncology Group

New pap smear applications


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  • Aviki EM, Rauh-Hain JA, Clark RM, Hall TR, Berkowitz LR, Boruta DM, Growdon WB, Schorge JO, Goodman A. Gynecologic Oncologist as surgical consultant: Intraoperative consultations during general gynecologic surgery as an important focus of gynecologic oncology training. Gynecol Oncol 2015; 137:93-7. PubMed
  • Joseph N, Clark RM, Dizon DS, Lee MS, Goodman A, Boruta D, Schorge JO, Del Carmen MG, Growdon WB. Delay in Chemotherapy Administration Impacts Survival in Elderly Patients with Epithelial Ovarian Cancer. Gynecol Oncol 2015. PubMed
  • Clark RM, Lee MS, Alejandro Rauh-Hain J, Hall T, Boruta DM, Del Carmen MG, Goodman A, Schorge JO, Growdon WB. Surgical Apgar Score and prediction of morbidity in women undergoing hysterectomy for malignancy. Gynecol Oncol 2015; 136:516-20. PubMed
  • Goodman A. HPV testing as a screen for cervical cancer. BMJ 2015; 350:h2372. PubMed
  • Chuang L, Moore KN, Creasman WT, Goodman A, Henriquez Cooper H, Price FV, Conner MG, Gupta V, Gallion HH, Husseinzadeh N, Duarte J, Vu QH, Sanchez JA, Kanis MJ. Teaching Gynecologic Oncology in Low Resource Settings: A Collaboration of Health Volunteers Overseas and the Society of Gynecologic Oncology. Gynecol Oncol 2014. PubMed
  • Lefkowits C, Sukumvanich P, Claxton R, Courtney-Brooks M, Kelley JL, McNeil MA, Goodman A. Needs assessment of palliative care education in gynecologic oncology fellowship: We're not teaching what we think is most important. Gynecol Oncol 2014. PubMed
  • Vargas R, Rauh-Hain JA, Clemmer J, Clark RM, Goodman A, Growdon WB, Schorge JO, Del Carmen MG, Horowitz NS, Boruta DM. Tumor size, depth of invasion, and histologic grade as prognostic factors of lymph node involvement in endometrial cancer: A SEER analysis. Gynecol Oncol 2014; 133:216-20. PubMed
  • Foley OW, Rauh-Hain JA, Clark RM, Goodman A, Growdon WB, Boruta DM, Schorge JO, Del Carmen MG. Intraoperative Radiation Therapy in the Management of Gynecologic Malignancies. Am J Clin Oncol 2014. PubMed
  • Williams KA, Labidi-Galy SI, Terry KL, Vitonis AF, Welch WR, Goodman A, Cramer DW. Prognostic significance and predictors of the neutrophil-to-lymphocyte ratio in ovarian cancer. Gynecol Oncol 2014; 132:542-50. PubMed
  • Guseh SH, Rauh-Hain JA, Tambouret RH, Davis M, Clark RM, Boruta DM, Goodman A, Growdon WB, Schorge JO, del Carmen MG. Transitional cell carcinoma of the ovary: a case-control study. Gynecol Oncol 2014; 132:649-53. PubMed
  • Rauh-Hain JA, Vargas RJ, Clemmer J, Clark RM, Bradford LS, Growdon WB, Goodman A, Boruta DM, Schorge JO, Del Carmen MG. Mucinous Adenocarcinoma of the Endometrium Compared With Endometrioid Endometrial Cancer: A SEER Analysis. Am J Clin Oncol 2014. PubMed
  • Goodman A, Nour N. Cervical cancer screening: the complex interplay of medical infrastructure, society, and culture. Oncologist 2014; 19:315-7. PubMed
  • Rauh-Hain JA, Clemmer J, Clark RM, Bradford LS, Growdon WB, Goodman A, Boruta DM, Schorge JO, del Carmen MG. Racial disparities and changes in clinical characteristics and survival for vulvar cancer over time. Am J Obstet Gynecol 2013; 209:468.e1-468.e10. PubMed
  • Rauh-Hain JA, Clemmer JT, Bradford LS, Clark RM, Growdon WB, Goodman A, Boruta DM, Schorge JO, del Carmen MG. Racial disparities in cervical cancer survival over time. Cancer 2013; 119:3644-52. PubMed
  • Penson RT, Goodman A, Growdon WB, Borger DR, Lee SI, Oliva E. Case records of the Massachusetts General Hospital. Case 14-2013. A 70-year-old woman with vaginal bleeding. N Engl J Med 2013; 368:1827-35. PubMed
  • Diver E, O'Connor O, Garrett L, Boruta D, Goodman A, Del Carmen M, Schorge J, Mueller P, Growdon W. Modest benefit of total parenteral nutrition and chemotherapy after venting gastrostomy tube placement. Gynecol Oncol 2013; 129:332-5. PubMed
  • Moulder JK, Garrett LA, Salazar GM, Goodman A. The role of radical surgery in the management of acquired uterine arteriovenous malformation. 2013; 6:303-10. PubMed
  • Bradford L, Goodman A. Cervical cancer screening and prevention in low-resource settings. Clin Obstet Gynecol 2013; 56:76-87. PubMed
  • Goodman A, Clark RM, Bradford LS. Caring for women with gynecologic cancers around the world: the need for global health training in gynecologic oncology fellowship programs. Am J Clin Oncol 2012; 35:511-3. PubMed
  • Honigberg MC, Bradford LS, Prabhakar AM, Hariri LP, Goodman A. Hypercalcemia associated with a malignant brenner tumor arising from a mature cystic teratoma. 2012; 5:592-600. PubMed
  • Bradford LS, Goodman A. Suffer little children. J Pastoral Care Counsel 2012; 66:9:1-2. PubMed
  • McCann CK, Growdon WB, Munro EG, Del Carmen MG, Boruta DM, Schorge JO, Goodman A. Prognostic Significance of Splenectomy as Part of Initial Cytoreductive Surgery in Ovarian Cancer. Ann Surg Oncol 2011. PubMed
  • Rauh-Hain JA, Growdon WB, Rodriguez N, Goodman AK, Boruta DM, Schorge JO, Horowitz NS, Del Carmen MG. Carcinosarcoma of the ovary: A case-control study. Gynecol Oncol 2011. PubMed
  • Goodman A. Measuring success in ovarian cancer risk reducing strategies. Cancer 2011. PubMed
  • Cramer DW, Vitonis AF, Welch WR, Terry KL, Goodman A, Rueda BR, Berkowitz RS. Correlates of the preoperative level of CA125 at presentation of ovarian cancer. Gynecol Oncol 2010; 119:462-8. PubMed
  • Young RH, Goodman A, Penson RT, Russell AH, Uppot RN, Tambouret RH. Case records of the Massachusetts General Hospital. Case 8-2010. A 22-year-old woman with hypercalcemia and a pelvic mass. N Engl J Med 2010; 362:1031-40. PubMed
  • Sarosy GA, Hussain MM, Seiden MV, Fuller AF, Nikrui N, Goodman A, Minasian L, Reed E, Steinberg SM, Kohn EC. Ten-year follow-up of a phase 2 study of dose-intense paclitaxel with cisplatin and cyclophosphamide as initial therapy for poor-prognosis, advanced-stage epithelial ovarian cancer. Cancer 2010; 116:1476-84. PubMed
  • Xian W, Miron A, Roh M, Semmel DR, Yassin Y, Garber J, Oliva E, Goodman A, Mehra K, Berkowitz RS, Crum CP, Quade BJ. The Li-Fraumeni syndrome (LFS): a model for the initiation of p53 signatures in the distal Fallopian tube. J Pathol 2009; 220:17-23. PubMed
  • Mirabeau-Beale KL,Kornblith AB,Penson RT,Lee H,Goodman A,Campos SM,Duska L,Pereira L,Bryan J,Matulonis UA. Comparison of the quality of life of early and advanced stage ovarian cancer survivors. Gynecol Oncol 2009; 114:353-9. PubMed
  • Lu W, Matulonis UA, Doherty-Gilman A, Lee H, Dean-Clower E, Rosulek A, Gibson C, Goodman A, Davis RB, Buring JE, Wayne PM, Rosenthal DS, Penson RT. Acupuncture for chemotherapy-induced neutropenia in patients with gynecologic malignancies: a pilot randomized, sham-controlled clinical trial. J Altern Complement Med 2009; 15:745-53. PubMed
  • Goldstein MA,Goodman A,del Carmen MG,Wilbur DC. Case records of the Massachusetts General Hospital. Case 10-2009. A 23-year-old woman with an abnormal Papanicolaou smear. N Engl J Med 2009; 360:1337-44. PubMed
  • Olawaiye A,Del Carmen M,Tambouret R,Goodman A,Fuller A,Duska LR. Abdominal radical trachelectomy: Success and pitfalls in a general gynecologic oncology practice. Gynecol Oncol 2009; 112:506-10. PubMed
  • Olawaiye AB,Morgan JA,Goodman A,Fuller AF Jr,Penson RT. Epithelioid angiosarcoma of the uterus: a review of management. Arch Gynecol Obstet 2008; 278:401-4. PubMed
  • Olawaiye AB,Rauh-Hain JA,Withiam-Leitch M,Rueda B,Goodman A,del Carmen MG. Utility of pre-operative serum CA-125 in the management of uterine papillary serous carcinoma. Gynecol Oncol 2008; 110:293-8. PubMed
  • Olawaiye A, Withiam-Leitch M, Prabhakar H, Goodman A. An unusual presentation of endometrial cancer: a case report and literature review. Arch Gynecol Obstet 2008; 278:103-6. PubMed
  • Ko E,Lee S,Goodman A. Gemcitabine pulmonary toxicity in ovarian cancer. Oncologist 2008; 13:807-11. PubMed
  • Kornblith AB, Powell M, Regan MM, Bennett S, Krasner C, Moy B, Younger J, Goodman A, Berkowitz R, Winer E. Long-term psychosocial adjustment of older vs younger survivors of breast and endometrial cancer. Psychooncology 2007; 16:895-903. PubMed
  • Goodman A, Falzon M, Gelder C, George J. Central airway obstruction caused by a peripheral hamartoma. Lung Cancer 2007; 57:395-8. PubMed
  • Matulonis UA, Campos S, Duska L, Krasner CN, Atkinson T, Penson RT, Seiden MV, Verrill C, Fuller AF, Goodman A,. Phase I/II dose finding study of combination cisplatin and gemcitabine in patients with recurrent cervix cancer. Gynecol Oncol 2006; 103:160-4. PubMed
  • Penson RT, Campos SM, Seiden MV, Krasner C, Fuller AF, Goodman A, Roche M, Willman A, Muzikansky A, Matulonis UA,. A phase II study of fixed dose rate gemcitabine in patients with relapsed mlerian tumors. Int J Gynecol Cancer 2005; 15:1035-41. PubMed
  • Goodman A. Endometrial cancer with concurrent ovarian malignancy: assessing the risks. Obstet Gynecol 2005; 106:680-1. PubMed
  • Spiryda LB, Fuller AF, Goodman A. Aggressive locally recurrent vulvar cancer: review of cases presented to Massachusetts General Hospital 1990 to present. Int J Gynecol Cancer 2005; 15:884-9. PubMed
  • Penson RT, Seiden MV, Matulonis UA, Appleman LJ, Fuller AF, Goodman A, Campos SM, Clark JW, Roche M, Eder JP. A phase I clinical trial of continual alternating etoposide and topotecan in refractory solid tumours. Br J Cancer 2005; 93:54-9. PubMed
  • Rezzani R, Rodella L, Bianchi R, Goodman AI, Lianos EA. Protective effects of heme-oxygenase expression in cyclosporine A--induced injury. Curr Neurovasc Res 2005; 2:157-61. PubMed
  • Duska LR, Berkowitz R, Matulonis U, Muto M, Goodman A, McIntyre JF, Klein A, Atkinson T, Seiden MV, Campos S. A pilot trial of TAC (paclitaxel, doxorubicin, and carboplatin) chemotherapy with filgastrim (r-metHuG-CSF) support followed by radiotherapy in patients with "high-risk" endometrial cancer. Gynecol Oncol 2004; 96:198-203. PubMed
  • Anhang R, Goodman A, Goldie SJ. HPV communication: review of existing research and recommendations for patient education. CA Cancer J Clin 2004; 54:248-59. PubMed
  • Fleming GF, Brunetto VL, Cella D, Look KY, Reid GC, Munkarah AR, Kline R, Burger RA, Goodman A, Burks RT. Phase III trial of doxorubicin plus cisplatin with or without paclitaxel plus filgrastim in advanced endometrial carcinoma: a Gynecologic Oncology Group Study. J Clin Oncol 2004; 22:2159-66. PubMed
  • Penson RT, Seiden MV, Goodman A, Fuller AF, Berkowitz RS, Matulonis UA, Krasner C, Lee H, Atkinson T, Campos SM,. Phase I trial of escalating doses of topotecan in combination with a fixed dose of pegylated liposomal doxorubicin in women with mlerian malignancies. Gynecol Oncol 2004; 93:702-7. PubMed
  • Penson RT, Oliva E, Skates SJ, Glyptis T, Fuller AF, Goodman A, Seiden MV. Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samples. Gynecol Oncol 2004; 93:98-106. PubMed
  • Dinh TA, Oliva EA, Fuller AF, Lee H, Goodman A. The treatment of uterine leiomyosarcoma. Results from a 10-year experience (1990-1999) at the Massachusetts General Hospital. Gynecol Oncol 2004; 92:648-52. PubMed
  • del Carmen MG, Fuller AF, Matulonis U, Horick NK, Goodman A, Duska LR, Penson R, Campos S, Roche M, Seiden MV. Phase II trial of anastrozole in women with asymptomatic mlerian cancer. Gynecol Oncol 2003; 91:596-602. PubMed
  • Goodman A, Wilbur DC. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 32-2003. A 37-year-old woman with atypical squamous cells on a Papanicolaou smear. N Engl J Med 2003; 349:1555-64. PubMed
  • del Carmen MG, Lovett D, Goodman A. A case of Mlerian adenosarcoma of the uterus treated with liposomal doxorubicin. Gynecol Oncol 2003; 88:456-8. PubMed
  • El Khoury J, Stikkelbroeck MM, Goodman A, Rubin RH, Cosimi AB, Fishman JA. Postmenopausal tubo-ovarian abscess due to Pseudomonas aeruginosa in a renal transplant patient: a case report and review of the literature. Transplantation 2001; 72:1241-4. PubMed
  • Penson RT, Supko JG, Seiden MV, Fuller AF, Berkowitz RS, Goodman A, Campos SM, MacNeill KM, Cook S, Matulonis UA. A Phase I-II study of 96-hour infusional topotecan and paclitaxel for patients with recurrent Mlerian tumors. Cancer 2001; 92:1156-67. PubMed
  • Campos SM, Penson RT, Mays AR, Berkowitz RS, Fuller AF, Goodman A, Matulonis UA, Muzikansky A, Seiden MV. The clinical utility of liposomal doxorubicin in recurrent ovarian cancer. Gynecol Oncol 2001; 81:206-12. PubMed
  • Goodman A, Houck K. Anxiety and uncertainty in informed decision making. J Womens Health Gend Based Med 2001; 10:93-4. PubMed
  • del Carmen MG, McIntyre JF, Fuller AF, Nikrui N, Goodman A. Intraoperative radiation therapy in the treatment of pelvic gynecologic malignancies: a review of fifteen cases. Gynecol Oncol 2000; 79:457-62. PubMed
  • Suh-Burgmann EJ, Whall-Strojwas D, Chang Y, Hundley D, Goodman A. Risk factors for cervical stenosis after loop electrocautery excision procedure. Obstet Gynecol 2000; 96:657-60. PubMed
  • Cook S, Penson R, Duska L, Nikrui N, Goodman A, Fuller A, Seiden M. Efficacy and hematologic toxicity of salvage chemotherapy following stem cell-supported high-dose chemotherapy in women with recurrent ovarian cancer. Gynecol Oncol 2000; 77:48-54. PubMed
  • Goodman A. Role of routine human papillomavirus subtyping in cervical screening. Curr Opin Obstet Gynecol 2001; 12:11-4. PubMed
  • Weitzel JN, Ding S, Larson GP, Nelson RA, Goodman A, Grendys EC, Ball HG, Krontiris TG. The HRAS1 minisatellite locus and risk of ovarian cancer. Cancer Res 2000; 60:259-61. PubMed
  • Owusu-Darko S, Rauh-Hain JA, Horowitz NS, Goodman A, Schorge JO, Del Carmen MG. Comparison of outcomes in patients with early-stage mucinous endometrial cancer and those with endometrioid endometrial cancer, with and without adjuvant therapy. J Reprod Med 2015; 59:527-33. PubMed
  • Rauh-Hain JA, Shoni M, Schorge JO, Goodman A, Horowitz NS, del Carmen MG. Prognostic determinants in patients with uterine and ovarian carcinosarcoma. J Reprod Med 2013; 58:297-304. PubMed
  • Rauh-Hain JA, Goodman A, Boruta DM, Schorge JO, Horowitz NS, del Carmen MG. Endometrial stromal sarcoma: a clinicopathologic study of 29 patients. J Reprod Med 2015; 59:547-52. PubMed
  • Goodman A, Chaudhuri PM, Tobin-Enos NJ, Hutchinson ML. The false negative rate of cervical smears in high risk HIV seropositive and seronegative women. Int J Gynecol Cancer 2001; 10:27-32. PubMed
  • del Carmen MG, McIntyre JF, Goodman A. The role of intraoperative radiation therapy (IORT) in the treatment of locally advanced gynecologic malignancies. Oncologist 2000; 5:18-25. PubMed
  • Goodman A. Laparoscopy versus laparotomy in the surgical management of gynecologic disease in older women: a shifting paradigm. Menopause 2010; 17:19-20. PubMed
  • Garrett LA, Growdon WB, Goodman A, Boruta DM, Schorge JO, del Carmen MG. Endometriosis-associated ovarian malignancy: a retrospective analysis of presentation, treatment, and outcome. J Reprod Med 2014; 58:469-76. PubMed
  • Goodman A. Abnormal genital tract bleeding. Clin Cornerstone 2000; 3:25-35. PubMed
  • Goodman A, Cagliero E. Megestrol-induced clinical adrenal insufficiency. Eur J Gynaecol Oncol 2000; 21:117-8. PubMed
  • Houck K, Avis NE, Gallant JM, Fuller AF, Goodman A. Quality of life in advanced ovarian cancer: identifying specific concerns. J Palliat Med 2005; 2:397-402. PubMed
  • Feltmate CM, Duska LR, Chang Y, Flynn CE, Nikrui N, Kiggundu E, Goodman A, Fuller AF, McIntyre JF. Predictors of recurrence in surgical stage II endometrial adenocarcinoma. Gynecol Oncol 1999; 73:407-11. PubMed
  • Duska LR, Penson R, Supko JG, Finkelstein DM, Makastorsis T, Gallagher J, Borden K, Goodman A, Fuller AF, Nikrui N, Seiden MV. A Phase I study of continuous infusion doxorubicin and paclitaxel chemotherapy with granulocyte colony-stimulating factor for relapsed epithelial ovarian cancer. Clin Cancer Res 1999; 5:1299-305. PubMed
  • Pitris C, Goodman A, Boppart SA, Libus JJ, Fujimoto JG, Brezinski ME. High-resolution imaging of gynecologic neoplasms using optical coherence tomography. Obstet Gynecol 1999; 93:135-9. PubMed
  • Goodman A, Penson RT, Blatman R, McIntyre J, Gioiella ME, Chabner BA, Lynch TJ. A staff dialogue on a socially distanced patient: psychosocial issues faced by patients, their families, and caregivers. Oncologist 1999; 4:417-24. PubMed
  • Goodman AK, Friedman SM, Beatrice ST, Bart SW. Rubella in the workplace: the need for employee immunization. Am J Public Health 1987; 77:725-6. PubMed