Photo of Curtis L. Cetrulo,  Jr., MD

Curtis L. Cetrulo, Jr., MD

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 643-7294

Curtis L. Cetrulo, Jr., MD

Massachusetts General Hospital

EDUCATIONAL TITLES

  • Assistant Professor, Surgery, Harvard Medical School
  • Plastic and Reconstructive Surgery, Surgery, Massachusetts General Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

The Vascularized Composite Tissue Allotransplantation Laboratory of the Transplantation Biology Research Center is investigating tolerance induction strategies for hand and face transplantation (vascularized composite tissue allografts or VCA) in the immunogenetically-defined MGH miniature swine model. These transplants can replace tissue defects following cancer or injury. Current research efforts are directed toward use of mixed hematopoietic chimerism to induce transplantation tolerance to VCA and toward exploring the immunologic mechanisms involved in tolerance and rejection of the skin component of the VCA.

 

Publications

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  • Kobraei EM, Eberlin KR, Ricci JA, Reish RG, Winograd JM, Cetrulo CL. GHOST Protocol: Greatest Healing Opportunity for Soft Tissue, a Treatment Paradigm for Complex Sarcoma Reconstruction. Am Surg 2015; 81:557-63. PubMed
  • Reish RG, Lin A, Phillips NA, Winograd J, Liao EC, Cetrulo CL, Smith BL, Austen WG, Colwell AS. Breast reconstruction outcomes after nipple-sparing mastectomy and radiation therapy. Plast Reconstr Surg 2015; 135:959-66. PubMed
  • Madariaga ML, Michel SG, La Muraglia GM, Sihag S, Leonard DA, Farkash EA, Colvin RB, Cetrulo CL, Huang CA, Sachs DH, Madsen JC, Allan JS. Recipient-Matching of Passenger Leukocytes Prolongs Survival of Donor Lung Allografts in Miniature Swine. Transplantation 2015. PubMed
  • Chadha R, Leonard DA, Kurtz JM, Cetrulo CL. The unique immunobiology of the skin: implications for tolerance of vascularized composite allografts. Curr Opin Organ Transplant 2014. PubMed
  • Reish RG, Lin AM, Austen WG, Winograd J, Liao EC, Cetrulo CL, Smith BL, Colwell AS. Abstract 25: breast reconstruction outcomes after nipple-sparing mastectomy and radiation therapy. Plast Reconstr Surg 2014; 133:991. PubMed
  • Colwell AS, Tessler O, Lin AM, Liao E, Winograd J, Cetrulo CL, Tang R, Smith BL, Austen WG. Breast reconstruction following nipple-sparing mastectomy: predictors of complications, reconstruction outcomes, and 5-year trends. Plast Reconstr Surg 2014; 133:496-506. PubMed
  • Cetrulo CL, Knox KR, Brown DJ, Ashinoff RL, Dobryansky M, Ceradini DJ, Capla JM, Chang EI, Bhatt KA, McCarthy JG, Gurtner GC. Stem cells and distraction osteogenesis: endothelial progenitor cells home to the ischemic generate in activation and consolidation. Plast Reconstr Surg 2005; 116:1053-64; discussion 1065-7. PubMed