Deborah Burstein, PhD

Beth Israel Deaconess Medical Center

Beth Israel Deaconess Medical Center
Phone: (617) 667-3349
Fax: (617) 667-7021


dburstei@bidmc.harvard.edu

Deborah Burstein, PhD

Beth Israel Deaconess Medical Center

EDUCATIONAL TITLES

  • Associate Professor, Radiology, Harvard Medical School
  • Associate Professor, Radiology, Beth Israel Deaconess Medical Center

Research Abstract

Our research focus is on Magnetic Resonance Imaging (MRI) of animal models of cancer. Our facilities include an 8.5T vertical 9 cm bore MRI unit, and a 4.7T horizontal 40 cm bore unit. Animal models from mice to rabbits can be studies within these systems. Pulse sequences include standard T1 and T2 weighted sequences, diffusion imaging, magnetization transfer, perfusion, and contrast enhanced studies. Personnel are available to assist in the planning and MRI scanning.

Publications

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  • Li W, Scheidegger R, Wu Y, Edelman RR, Farley M, Krishnan N, Burstein D, Prasad PV. Delayed contrast-enhanced MRI of cartilage: Comparison of nonionic and ionic contrast agents. Magn Reson Med 2010; 64:1267-73. PubMed
  • Hunter DJ, Losina E, Guermazi A, Burstein D, Lassere MN, Kraus V. A Pathway and Approach to Biomarker Validation and Qualification for Osteoarthritis Clinical Trials. Curr Drug Targets 2010; 11:536-45. PubMed
  • Wu M, Orta L, Gil J, Li G, Hu A, Burstein DE. Immunohistochemical detection of XIAP and p63 in adenomatous hyperplasia, atypical adenomatous hyperplasia, bronchioloalveolar carcinoma and well-differentiated adenocarcinoma. Mod Pathol 2008; 21:553-8. PubMed
  • Burstein DE, Idrees MT, Li G, Wu M, Kalir T. Immunohistochemical detection of the X-linked inhibitor of apoptosis protein (XIAP) in cervical squamous intraepithelial neoplasia and squamous carcinoma. Ann Diagn Pathol 2008; 12:85-9. PubMed
  • Shtilbans V, Wu M, Burstein DE. Current overview of the role of Akt in cancer studies via applied immunohistochemistry. Ann Diagn Pathol 2008; 12:153-60. PubMed
  • Williams A, Shetty SK, Burstein D, Day CS, McKenzie C. Delayed gadolinium enhanced MRI of cartilage (dGEMRIC) of the first carpometacarpal (1CMC) joint: a feasibility study. Osteoarthritis Cartilage 2008; 16:530-2. PubMed
  • Gray ML, Burstein D, Kim YJ, Maroudas A. 2007 Elizabeth Winston Lanier Award Winner. Magnetic resonance imaging of cartilage glycosaminoglycan: basic principles, imaging technique, and clinical applications. J Orthop Res 2007; 26:281-91. PubMed
  • Emanuel PO, Phelps RG, Mudgil A, Shafir M, Burstein DE. Immunohistochemical detection of XIAP in melanoma. J Cutan Pathol 2008; 35:292-7. PubMed
  • Wu M, Orta L, Gil J, Li G, Hu A, Burstein DE. Immunohistochemical detection of XIAP and p63 in adenomatous hyperplasia, atypical adenomatous hyperplasia, bronchioloalveolar carcinoma and well-differentiated adenocarcinoma. Mod Pathol 2008. PubMed
  • Xiao GQ, Burstein DE. Cytologic findings of rhabdoid meningioma in cerebrospinal fluid. Acta Cytol 2008; 52:118-9. PubMed
  • Nagi C, Xiao GQ, Li G, Genden E, Burstein DE. Immunohistochemical detection of X-linked inhibitor of apoptosis in head and neck squamous cell carcinoma. Ann Diagn Pathol 2007; 11:402-6. PubMed
  • Williams A, Mikulis B, Krishnan N, Gray M, McKenzie C, Burstein D. Suitability of T(1Gd) as the dGEMRIC index at 1.5T and 3.0T. Magn Reson Med 2007; 58:830-4. PubMed
  • Baldassarri M, Goodwin JS, Farley ML, Bierbaum BE, Goldring SR, Goldring MB, Burstein D, Gray ML. Relationship between cartilage stiffness and dGEMRIC index: correlation and prediction. J Orthop Res 2007; 25:904-12. PubMed
  • Sun Y, Schmidt NO, Schmidt K, Doshi S, Rubin JB, Mulkern RV, Carroll R, Ziu M, Erkmen K, Poussaint TY, Black P, Albert M, Burstein D, Kieran MW. Perfusion MRI of U87 brain tumors in a mouse model. Magn Reson Med 2004; 51:893-9. PubMed
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