Photo of Edward E. Harlow,  PhD

Edward E. Harlow, PhD

Harvard Medical School

Harvard Medical School
Phone: (617) 432-1337
Fax: (617) 432-2452


ed_harlow@hms.harvard.edu

Edward E. Harlow, PhD

Harvard Medical School

EDUCATIONAL TITLES

  • Virginia and D.K. Ludwig Professor of Cancer Research and Teaching, Biological Chemistry and Molecular Pharmacology, Harvard Medical School
  • Head, Biological Chemistry and Molecular Pharmacology, Harvard Medical School

DF/HCC PROGRAM AFFILIATION

Publications

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  • Li W, Ai N, Wang S, Bhattacharya N, Vrbanac V, Collins M, Signoretti S, Hu Y, Boyce FM, Gravdal K, Halvorsen OJ, Nalwoga H, Akslen LA, Harlow E, Watnick RS. GRK3 is essential for metastatic cells and promotes prostate tumor progression. Proc Natl Acad Sci U S A 2014; 111:1521-6. PubMed
  • Baldwin A, Grueneberg DA, Hellner K, Sawyer J, Grace M, Li W, Harlow E, Munger K. Kinase requirements in human cells: V. Synthetic lethal interactions between p53 and the protein kinases SGK2 and PAK3. Proc Natl Acad Sci U S A 2010; 107:12463-8. PubMed
  • Vander Heiden MG, Christofk HR, Schuman E, Subtelny AO, Sharfi H, Harlow EE, Xian J, Cantley LC. Identification of small molecule inhibitors of pyruvate kinase M2. Biochem Pharmacol 2010; 79:1118-24. PubMed
  • Grueneberg DA, Li W, Davies JE, Sawyer J, Pearlberg J, Harlow E. Kinase requirements in human cells: IV. Differential kinase requirements in cervical and renal human tumor cell lines. Proc Natl Acad Sci U S A 2008; 105:16490-5. PubMed
  • Baldwin A,Li W,Grace M,Pearlberg J,Harlow E,Munger K,Grueneberg DA. Kinase requirements in human cells: II. Genetic interaction screens identify kinase requirements following HPV16 E7 expression in cancer cells. Proc Natl Acad Sci U S A 2008; 105:16478-83. PubMed
  • Grueneberg DA,Degot S,Pearlberg J,Li W,Davies JE,Baldwin A,Endege W,Doench J,Sawyer J,Hu Y,Boyce F,Xian J,Munger K,Harlow E. Kinase requirements in human cells: I. Comparing kinase requirements across various cell types. Proc Natl Acad Sci U S A 2008; 105:16472-7. PubMed
  • Bommi-Reddy A, Almeciga I, Sawyer J, Geisen C, Li W, Harlow E, Kaelin WG, Grueneberg DA. Kinase requirements in human cells: III. Altered kinase requirements in VHL-/- cancer cells detected in a pilot synthetic lethal screen. Proc Natl Acad Sci U S A 2008; 105:16484-9. PubMed