Photo of Frederick G. Barker,  MD

Frederick G. Barker, MD

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 724-8772
Fax: (617) 724-8769


barker@helix.mgh.harvard.edu

Frederick G. Barker, MD

Massachusetts General Hospital

EDUCATIONAL TITLES

  • Associate Professor, Neurosurgery, Harvard Medical School
  • Associate Visiting Surgeon, Neurosurgery, Massachusetts General Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

Clinical research on glioblastoma multiforme and other malignant gliomas, including trial design for phase I gene therapy trials, prognostic variable studies, radiation response in correlation with molecular markers (EGFR)

Publications

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  • Terry AR, Merker VL, Barker FG, Leffert L, Bateman BT, Souter I, Plotkin SR. Pregnancy complications in women with rare tumor suppressor syndromes affecting central and peripheral nervous system. Am J Obstet Gynecol 2015. PubMed
  • Jones PS, Aghi MK, Muzikansky A, Shih HA, Barker FG, Curry WT. Outcomes and patterns of care in adult skull base chordomas from the Surveillance, Epidemiology, and End Results (SEER) database. J Clin Neurosci 2014. PubMed
  • Jones PS, Aghi MK, Muzikansky A, Shih HA, Barker FG, Curry WT. Outcomes and patterns of care in adult skull base chondrosarcomas from the SEER database. J Clin Neurosci 2014. PubMed
  • Herr MW, Sethi RK, Meier JC, Chambers KJ, Remenschneider A, Chan A, Curry WT, Barker FG, Deschler DG, Lin DT. Esthesioneuroblastoma: an update on the massachusetts eye and ear infirmary and massachusetts general hospital experience with craniofacial resection, proton beam radiation, and chemotherapy. J Neurol Surg B Skull Base 2014; 75:58-64. PubMed
  • Plotkin SR, Merker VL, Muzikansky A, Barker FG, Slattery W. Natural history of vestibular schwannoma growth and hearing decline in newly diagnosed neurofibromatosis type 2 patients. Otol. Neurotol. 2013; 35:e50-6. PubMed
  • McDuff SG, Taich ZJ, Lawson JD, Sanghvi P, Wong ET, Barker FG, Hochberg FH, Loeffler JS, Warnke PC, Murphy KT, Mundt AJ, Carter BS, McDonald CR, Chen CC. Neurocognitive assessment following whole brain radiation therapy and radiosurgery for patients with cerebral metastases. J Neurol Neurosurg Psychiatry 2013; 84:1384-91. PubMed
  • Plotkin SR, Ardern-Holmes SL, Barker FG, Blakeley JO, Evans DG, Ferner RE, Hadlock TA, Halpin C, . Hearing and facial function outcomes for neurofibromatosis 2 clinical trials. Neurology 2013; 81:S25-32. PubMed
  • Terry AR, Barker FG, Leffert L, Bateman BT, Souter I, Plotkin SR. Neurofibromatosis type 1 and pregnancy complications: a┬ápopulation-based study. Am J Obstet Gynecol 2013. PubMed
  • Dilwali S, Lysaght A, Roberts D, Barker FG, McKenna MJ, Stankovic KM. Sporadic Vestibular Schwannomas Associated With Good Hearing Secrete Higher Levels of Fibroblast Growth Factor 2 Than Those Associated With Poor Hearing Irrespective of Tumor Size. Otol. Neurotol. 2013. PubMed
  • Jones PS, Dunn GP, Barker FG, Curry WT, Hochberg FH, Cahill DP. Molecular genetics of low-grade gliomas: genomic alterations guiding diagnosis and therapeutic intervention. 11th Annual Frye-Halloran Brain Tumor Symposium. Neurosurg Focus 2013; 34:E9. PubMed
  • Nunes FP, Merker VL, Jennings D, Caruso PA, di Tomaso E, Muzikansky A, Barker FG, Stemmer-Rachamimov A, Plotkin SR. Bevacizumab Treatment for Meningiomas in NF2: A Retrospective Analysis of 15 Patients. PLoS ONE 2013; 8:e59941. PubMed
  • Yanamadala V, Walcott BP, Nahed BV, Barker FG. Retrograde Third Ventriculocisternostomy from the Posterior Fossa. Neurosurgery 2012. PubMed
  • Plotkin SR, Merker VL, Halpin C, Jennings D, McKenna MJ, Harris GJ, Barker FG. Bevacizumab for progressive vestibular schwannoma in neurofibromatosis type 2: a retrospective review of 31 patients. Otol. Neurotol. 2012; 33:1046-52. PubMed
  • Terry AR, Barker FG, Leffert L, Bateman BT, Souter I, Plotkin SR. Outcomes of hospitalization in pregnant women with CNS neoplasms: a population-based study. 2012; 14:768-76. PubMed
  • Plotkin SR, Halpin C, McKenna MJ, Loeffler JS, Batchelor TT, Barker FG. Erlotinib for progressive vestibular schwannoma in neurofibromatosis 2 patients. Otol. Neurotol. 2010; 31:1135-43. PubMed
  • Cahill DP, Barker FG, Davis KR, Kalva SP, Sahai I, Frosch MP. Case records of the Massachusetts General Hospital. Case 10-2010. A 37-year-old woman with weakness and a mass in the brain. N Engl J Med 2010; 362:1326-33. PubMed
  • Curry WT, Carter BS, Barker FG. Racial, ethnic, and socioeconomic disparities in patient outcomes after craniotomy for tumor in adult patients in the United States, 1988-2004. Neurosurgery 2010; 66:427-37; discussion 437-8. PubMed
  • Truong MT, Kamat UR, Liebsch NJ, Curry WT, Lin DT, Barker FG, Loeffler JS, Chan AW. Proton radiation therapy for primary sphenoid sinus malignancies: treatment outcome and prognostic factors. Head Neck 2009; 31:1297-308. PubMed
  • Gabeau-Lacet D, Engler D, Gupta S, Scangas GA, Betensky RA, Barker FG, Loeffler JS, Louis DN, Mohapatra G. Genomic profiling of atypical meningiomas associates gain of 1q with poor clinical outcome. J Neuropathol Exp Neurol 2009; 68:1155-65. PubMed
  • Plotkin SR, Stemmer-Rachamimov AO, Barker FG, Halpin C, Padera TP, Tyrrell A, Sorensen AG, Jain RK, di Tomaso E. Hearing improvement after bevacizumab in patients with neurofibromatosis type 2. N Engl J Med 2009; 361:358-67. PubMed
  • Curry WT Jr,Barker FG 2nd. Racial, ethnic and socioeconomic disparities in the treatment of brain tumors. J Neurooncol 2009; 93:25-39. PubMed
  • Aghi MK,Batchelor TT,Louis DN,Barker FG 2nd,Curry WT Jr. Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q. J Neurooncol 2009; 93:115-20. PubMed
  • Vogelbaum MA, Asher AL, Kondziolka D, Boulis NM, Selden NR, Hoh BL, Barker FG. Modern treatment of cerebral metastases: Integrated Medical Learning(SM) at CNS 2007. J. Neurooncol. 2009; 93:89-105. PubMed
  • Plotkin SR,Halpin C,Blakeley JO,Slattery WH 3rd,Welling DB,Chang SM,Loeffler JS,Harris GJ,Sorensen AG,McKenna MJ,Barker FG 2nd. Suggested response criteria for phase II antitumor drug studies for neurofibromatosis type 2 related vestibular schwannoma. J Neurooncol 2009; 93:61-77. PubMed
  • Aghi MK,Carter BS,Cosgrove GR,Ojemann RG,Amin-Hanjani S,Martuza RL,Curry WT Jr,Barker FG 2nd. Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation. Neurosurgery 2009; 64:56-60; discussion 60. PubMed
  • Sher DJ, Henson JW, Avutu B, Hochberg FH, Batchelor TT, Martuza RL, Barker FG 2nd, Loeffler JS, Chakravarti A. The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma. J Neurooncol 2008; 88:43-50. PubMed
  • Aqel N, Barker F, Patel K, Naresh KN. In-situ mantle cell lymphoma--a report of two cases. Histopathology 2008; 52:256-60. PubMed
  • Barnholtz-Sloan JS, Maldonado JL, Williams VL, Curry WT, Rodkey EA, Barker FG 2nd, Sloan AE. Racial/ethnic differences in survival among elderly patients with a primary glioblastoma. J Neurooncol 2007; 85:171-80. PubMed
  • Aghi MK, Eskandar EN, Carter BS, Curry WT Jr, Barker FG 2nd. Increased prevalence of obesity and obesity-related postoperative complications in male patients with meningiomas. Neurosurgery 2007; 61:754-60; discussion 760-1. PubMed
  • Pelloski CE, Ballman KV, Furth AF, Zhang L, Lin E, Sulman EP, Bhat K, McDonald JM, Yung WK, Colman H, Woo SY, Heimberger AB, Suki D, Prados MD, Chang SM, Barker FG 2nd, Buckner JC, James CD, Aldape K. Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma. J Clin Oncol 2007; 25:2288-94. PubMed
  • Barker FG. Efficacy of prophylactic antibiotics against meningitis after craniotomy: a meta-analysis. Neurosurgery 2007; 60:887-94; discussion 887-94. PubMed
  • Ghogawala Z, Coumans JV, Benzel EC, Stabile LM, Barker FG. Ventral versus dorsal decompression for cervical spondylotic myelopathy: surgeons' assessment of eligibility for randomization in a proposed randomized controlled trial: results of a survey of the Cervical Spine Research Society. Spine 2007; 32:429-36. PubMed
  • Ulmer S, Braga TA, Barker FG, Lev MH, Gonzalez RG, Henson JW. Clinical and radiographic features of peritumoral infarction following resection of glioblastoma. Neurology 2006; 67:1668-70. PubMed
  • Pommier P, Liebsch NJ, Deschler DG, Lin DT, McIntyre JF, Barker FG, Adams JA, Lopes VV, Varvares M, Loeffler JS, Chan AW. Proton beam radiation therapy for skull base adenoid cystic carcinoma. Arch Otolaryngol Head Neck Surg 2006; 132:1242-9. PubMed
  • Barker FG. Brain metastasis. J Neurosurg 2006; 105:371-2; discussion 372-4. PubMed
  • Smith ER, Butler WE, Barker FG. Is there a "July phenomenon" in pediatric neurosurgery at teaching hospitals? J Neurosurg 2006; 105:169-76. PubMed
  • Eskandar E, Barker FG, Rabinov JD. Case records of the Massachusetts General Hospital. Case 21-2006. A 61-year-old man with left-sided facial pain. N Engl J Med 2006; 355:183-8. PubMed
  • Pelloski CE, Lin E, Zhang L, Yung WK, Colman H, Liu JL, Woo SY, Heimberger AB, Suki D, Prados M, Chang S, Barker FG, Fuller GN, Aldape KD. Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma. Clin Cancer Res 2006; 12:3935-41. PubMed
  • Barker FG, Chang SM. Improving resection of malignant glioma. Lancet Oncol 2006; 7:359-60. PubMed
  • Flickinger JC, Barker FG. Clinical results: radiosurgery and radiotherapy of cranial nerve schwannomas. Neurosurg Clin N Am 2006; 17:121-8. PubMed
  • Aghi M, Kluwe L, Webster MT, Jacoby LB, Barker FG, Ojemann RG, Mautner VF, MacCollin M. Unilateral vestibular schwannoma with other neurofibromatosis type 2-related tumors: clinical and molecular study of a unique phenotype. J Neurosurg 2006; 104:201-7. PubMed
  • Aghi M, Gaviani P, Henson JW, Batchelor TT, Louis DN, Barker FG. Magnetic resonance imaging characteristics predict epidermal growth factor receptor amplification status in glioblastoma. Clin Cancer Res 2005; 11:8600-5. PubMed
  • Chang SM, Barker FG. Marital status, treatment, and survival in patients with glioblastoma multiforme. Cancer 2005; 104:1975-84. PubMed
  • Amin-Hanjani S, Butler WE, Ogilvy CS, Carter BS, Barker FG. Extracranial-intracranial bypass in the treatment of occlusive cerebrovascular disease and intracranial aneurysms in the United States between 1992 and 2001: a population-based study. J Neurosurg 2005; 103:794-804. PubMed
  • Barker FG, Carter BS. Synthesizing medical evidence: systematic reviews and metaanalyses. Neurosurg Focus 2005; 19:E5. PubMed
  • Mavrakis AN, Halpern EF, Barker FG, Gonzalez RG, Henson JW. Diagnostic evaluation of patients with a brain mass as the presenting manifestation of cancer. Neurology 2005; 65:908-11. PubMed
  • Curry WT, Butler WE, Barker FG. Rapidly rising incidence of cerebrospinal fluid shunting procedures for idiopathic intracranial hypertension in the United States, 1988-2002. Neurosurgery 2005; 57:97-108; discussion 97-108. PubMed
  • Chan AW, Black P, Ojemann RG, Barker FG, Kooy HM, Lopes VV, McKenna MJ, Shrieve DC, Martuza RL, Loeffler JS. Stereotactic radiotherapy for vestibular schwannomas: favorable outcome with minimal toxicity. Neurosurgery 2005; 57:60-70; discussion 60-70. PubMed
  • Curry WT, McDermott MW, Carter BS, Barker FG. Craniotomy for meningioma in the United States between 1988 and 2000: decreasing rate of mortality and the effect of provider caseload. J Neurosurg 2005; 102:977-86. PubMed
  • Barker FG, McDermott MW. Prizes, lectures, and awards of the American Association of Neurological Surgeons/Congress of Neurological Surgeons Section on Tumors. Neurosurg Focus 2005; 18:e11. PubMed
  • Barker FG. Surgical and radiosurgical management of brain metastases. Surg Clin North Am 2005; 85:329-45. PubMed
  • Barker FG, Curry WT, Carter BS. Surgery for primary supratentorial brain tumors in the United States, 1988 to 2000: the effect of provider caseload and centralization of care. Neuro-oncol 2005; 7:49-63. PubMed
  • Chiocca EA, Abbed KM, Tatter S, Louis DN, Hochberg FH, Barker F, Kracher J, Grossman SA, Fisher JD, Carson K, Rosenblum M, Mikkelsen T, Olson J, Markert J, Rosenfeld S, Nabors LB, Brem S, Phuphanich S, Freeman S, Kaplan R, Zwiebel J. A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. Mol Ther 2004; 10:958-66. PubMed
  • Ghogawala Z, Benzel EC, Amin-Hanjani S, Barker FG, Harrington JF, Magge SN, Strugar J, Coumans JV, Borges LF. Prospective outcomes evaluation after decompression with or without instrumented fusion for lumbar stenosis and degenerative Grade I spondylolisthesis. J Neurosurg Spine 2004; 1:267-72. PubMed
  • Barker FG, Amin-Hanjani S. Changing neurosurgical workload in the United States, 1988-2001: craniotomy other than trauma in adults. Neurosurgery 2004; 55:506-17; discussion 517-8. PubMed
  • Barker FG, Linskey ME. History of the AANS/CNS joint section on tumors and preface to the 20th anniversary Journal of Neuro-Oncology Special Issue. J Neurooncol 2004; 69:1-18. PubMed
  • Rabinov JD, Barker FG, McKenna MJ, Curtin HD. Virtual cisternoscopy: 3D MRI models of the cerebellopontine angle for lesions related to the cranial nerves. Skull Base 2005; 14:93-9; discussion 99. PubMed
  • Smith ER, Butler WE, Barker FG. Craniotomy for resection of pediatric brain tumors in the United States, 1988 to 2000: effects of provider caseloads and progressive centralization and specialization of care. Neurosurgery 2004; 54:553-63; discussion 563-5. PubMed
  • Barker FG. Craniotomy for the resection of metastatic brain tumors in the U.S., 1988-2000: decreasing mortality and the effect of provider caseload. Cancer 2004; 100:999-1007. PubMed
  • Smith ER, Butler WE, Barker FG. In-hospital mortality rates after ventriculoperitoneal shunt procedures in the United States, 1998 to 2000: relation to hospital and surgeon volume of care. J Neurosurg Spine 2004; 100:90-7. PubMed
  • Amin-Hanjani S, Ogilvy CS, Barker FG. Does intracisternal thrombolysis prevent vasospasm after aneurysmal subarachnoid hemorrhage? A meta-analysis. Neurosurgery 2004; 54:326-34; discussion 334-5. PubMed
  • Barker FG, Amin-Hanjani S, Butler WE, Hoh BL, Rabinov JD, Pryor JC, Ogilvy CS, Carter BS. Age-dependent differences in short-term outcome after surgical or endovascular treatment of unruptured intracranial aneurysms in the United States, 1996-2000. Neurosurgery 2003; 54:18-28; discussion 28-30. PubMed
  • Ramsey MJ, McKenna MJ, Barker FG. Superior semicircular canal dehiscence syndrome. Case report. J Neurosurg 2004; 100:123-4. PubMed
  • Eskandar EN, Flaherty A, Cosgrove GR, Shinobu LA, Barker FG. Surgery for Parkinson disease in the United States, 1996 to 2000: practice patterns, short-term outcomes, and hospital charges in a nationwide sample. J Neurosurg 2003; 99:863-71. PubMed
  • Barker FG, Klibanski A, Swearingen B. Transsphenoidal surgery for pituitary tumors in the United States, 1996-2000: mortality, morbidity, and the effects of hospital and surgeon volume. J Clin Endocrinol Metab 2003; 88:4709-19. PubMed
  • Weber DC, Chan AW, Bussiere MR, Harsh GR, Ancukiewicz M, Barker FG, Thornton AT, Martuza RL, Nadol JB, Chapman PH, Loeffler JS. Proton beam radiosurgery for vestibular schwannoma: tumor control and cranial nerve toxicity. Neurosurgery 2003; 53:577-86; discussion 586-8. PubMed
  • Barker FG, Butler WE, Lyons S, Cascio E, Ogilvy CS, Loeffler JS, Chapman PH. Dose-volume prediction of radiation-related complications after proton beam radiosurgery for cerebral arteriovenous malformations. J Neurosurg 2003; 99:254-63. PubMed
  • Barker FG, Carter BS, Ojemann RG, Jyung RW, Poe DS, McKenna MJ. Surgical excision of acoustic neuroma: patient outcome and provider caseload. Laryngoscope 2003; 113:1332-43. PubMed
  • Hoh BL, Rabinov JD, Pryor JC, Carter BS, Barker FG. In-hospital morbidity and mortality after endovascular treatment of unruptured intracranial aneurysms in the United States, 1996-2000: effect of hospital and physician volume. AJNR Am J Neuroradiol 2003; 24:1409-20. PubMed
  • Chang SM, Parney IF, McDermott M, Barker FG, Schmidt MH, Huang W, Laws ER, Lillehei KO, Bernstein M, Brem H, Sloan AE, Berger M,. Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project. J Neurosurg 2003; 98:1175-81. PubMed
  • Kalkanis SN, Eskandar EN, Carter BS, Barker FG. Microvascular decompression surgery in the United States, 1996 to 2000: mortality rates, morbidity rates, and the effects of hospital and surgeon volumes. Neurosurgery 2003; 52:1251-61; discussion 1261-. PubMed
  • Barker FG, Amin-Hanjani S, Butler WE, Ogilvy CS, Carter BS. In-hospital mortality and morbidity after surgical treatment of unruptured intracranial aneurysms in the United States, 1996-2000: the effect of hospital and surgeon volume. Neurosurgery 2003; 52:995-1007; discussion 1007. PubMed
  • Rabinov JD, Lee PL, Barker FG, Louis DN, Harsh GR, Cosgrove GR, Chiocca EA, Thornton AF, Loeffler JS, Henson JW, Gonzalez RG. In vivo 3-T MR spectroscopy in the distinction of recurrent glioma versus radiation effects: initial experience. Radiology 2002; 225:871-9. PubMed
  • Barker FG. Efficacy of prophylactic antibiotic therapy in spinal surgery: a meta-analysis. Neurosurgery 2002; 51:391-400; discussion 400-1. PubMed
  • Chang SM, Barker FG, Schmidt MH, Sloan AE, Kasper R, Phillips L, Shih K, Hariharan S, Berger MS. Clinical trial participation among patients enrolled in the Glioma Outcomes Project. Cancer 2002; 94:2681-7. PubMed
  • Barker FG, Chang SM, Larson DA, Sneed PK, Wara WM, Wilson CB, Prados MD. Age and radiation response in glioblastoma multiforme. Neurosurgery 2002; 49:1288-97; discussion 1297-. PubMed
  • Barker FG, Simmons ML, Chang SM, Prados MD, Larson DA, Sneed PK, Wara WM, Berger MS, Chen P, Israel MA, Aldape KD. EGFR overexpression and radiation response in glioblastoma multiforme. Int J Radiat Oncol Biol Phys 2001; 51:410-8. PubMed
  • Barker FG, Amin-Hanjani S, Butler WE, Lyons S, Ojemann RG, Chapman PH, Ogilvy CS. Temporal clustering of hemorrhages from untreated cavernous malformations of the central nervous system. Neurosurgery 2001; 49:15-24; discussion 24-5. PubMed
  • Simmons ML, Lamborn KR, Takahashi M, Chen P, Israel MA, Berger MS, Godfrey T, Nigro J, Prados M, Chang S, Barker FG, Aldape K. Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients. Cancer Res 2001; 61:1122-8. PubMed
  • Wackym PA, King WA, Poe DS, Meyer GA, Ojemann RG, Barker FG, Walsh PR, Staecker H. Adjunctive use of endoscopy during acoustic neuroma surgery. Laryngoscope 1999; 109:1193-201. PubMed
  • Swearingen B, Biller BM, Barker FG, Katznelson L, Grinspoon S, Klibanski A, Zervas NT. Long-term mortality after transsphenoidal surgery for Cushing disease. Ann Intern Med 1999; 130:821-4. PubMed
  • Swearingen B, Barker FG, Zervas NT. The management of pituitary adenomas: the MGH experience. Clin Neurosurg 1999; 45:48-56. PubMed
  • Loeffler JS, Barker FG, Chapman PH. Role of radiosurgery in the management of central nervous system metastases. Cancer Chemother Pharmacol 1999; 43 Suppl:S11-4. PubMed
  • Wackym PA, King WA, Barker FG, Poe DS. Endoscope-assisted vestibular neurectomy. Laryngoscope 1998; 108:1787-93. PubMed
  • Swearingen B, Barker FG, Katznelson L, Biller BM, Grinspoon S, Klibanski A, Moayeri N, Black PM, Zervas NT. Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly. J Clin Endocrinol Metab 1998; 83:3419-26. PubMed
  • Chang SM, Barker FG, Huhn SL, Nicholas MK, Page M, Rabbitt J, Prados MD. High dose oral tamoxifen and subcutaneous interferon alpha-2a for recurrent glioma. J Neurooncol 1998; 37:169-76. PubMed
  • Barker FG, Chang SM, Gutin PH, Malec MK, McDermott MW, Prados MD, Wilson CB. Survival and functional status after resection of recurrent glioblastoma multiforme. Neurosurgery 1998; 42:709-20; discussion 720-3. PubMed
  • Barker FG. Repairing holes in the head: a history of cranioplasty. Neurosurgery 1997; 41:999. PubMed
  • Barker FG, Chang SM, Huhn SL, Davis RL, Gutin PH, McDermott MW, Wilson CB, Prados MD. Age and the risk of anaplasia in magnetic resonance-nonenhancing supratentorial cerebral tumors. Cancer 1997; 80:936-41. PubMed
  • Barker FG, Chang SM, Valk PE, Pounds TR, Prados MD. 18-Fluorodeoxyglucose uptake and survival of patients with suspected recurrent malignant glioma. Cancer 1997; 79:115-26. PubMed
  • Barker FG, Jannetta PJ, Bissonette DJ, Jho HD. Trigeminal numbness and tic relief after microvascular decompression for typical trigeminal neuralgia. Neurosurgery 1997; 40:39-45. PubMed
  • Barker FG, Chen P, Furman F, Aldape KD, Edwards MS, Israel MA. P16 deletion and mutation analysis in human brain tumors. J Neurooncol 1997; 31:17-23. PubMed
  • Ogilvy CS, Barker FG, Joseph MP, Cheney ML, Swearingen B, Crowell RM. Transfacial transclival approach for midline posterior circulation aneurysms. Neurosurgery 1996; 39:736-41; discussion 742. PubMed
  • Barker FG. Analysis of the relationship between long-term operative success and a transient or delayed operative side effect. Neurosurgery 1996; 39:412-5; discussion 415-6. PubMed
  • Barker FG, Jannetta PJ, Babu RP, Pomonis S, Bissonette DJ, Jho HD. Long-term outcome after operation for trigeminal neuralgia in patients with posterior fossa tumors. J Neurosurg 1996; 84:818-25. PubMed
  • Barker FG, Jannetta PJ, Bissonette DJ, Larkins MV, Jho HD. The long-term outcome of microvascular decompression for trigeminal neuralgia. N Engl J Med 1996; 334:1077-83. PubMed
  • Barker FG, Davis RL, Chang SM, Prados MD. Necrosis as a prognostic factor in glioblastoma multiforme. Cancer 1996; 77:1161-6. PubMed
  • Barker FG, Prados MD, Chang SM, Davis RL, Gutin PH, Lamborn KR, Larson DA, McDermott MW, Sneed PK, Wilson CB. Bromodeoxyuridine labeling index in glioblastoma multiforme: relation to radiation response, age, and survival. Int J Radiat Oncol Biol Phys 1996; 34:803-8. PubMed
  • Barker FG, Prados MD, Chang SM, Gutin PH, Lamborn KR, Larson DA, Malec MK, McDermott MW, Sneed PK, Wara WM, Wilson CB. Radiation response and survival time in patients with glioblastoma multiforme. J Neurosurg 1996; 84:442-8. PubMed
  • Butler WE, Barker FG, Crowell RM. Patients with polycystic kidney disease would benefit from routine magnetic resonance angiographic screening for intracerebral aneurysms: a decision analysis. Neurosurgery 1996; 38:506-15; discussion 515-6. PubMed
  • Barker FG, Ogilvy CS. Efficacy of prophylactic nimodipine for delayed ischemic deficit after subarachnoid hemorrhage: a metaanalysis. J Neurosurg 1996; 84:405-14. PubMed
  • Fick J, Barker FG, Dazin P, Westphale EM, Beyer EC, Israel MA. The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro. Proc Natl Acad Sci U S A 1995; 92:11071-5. PubMed
  • Barker FG, Israel MA. The molecular biology of brain tumors. Neurol Clin 1995; 13:701-21. PubMed
  • Chang SM, Barker FG, Larson DA, Bollen AW, Prados MD. Sarcomas subsequent to cranial irradiation. Neurosurgery 1995; 36:685-90. PubMed
  • Barker FG. Phineas among the phrenologists: the American crowbar case and nineteenth-century theories of cerebral localization. J Neurosurg 1995; 82:672-82. PubMed
  • Barker FG, Jannetta PJ, Bissonette DJ, Shields PT, Larkins MV, Jho HD. Microvascular decompression for hemifacial spasm. J Neurosurg 1995; 82:201-10. PubMed
  • Barker FG, Ogilvy CS, Chin JK, Joseph MP, Pile-Spellman J, Crowell RM. Transethmoidal transsphenoidal approach for embolization of a carotid-cavernous fistula. Case report. J Neurosurg 1994; 81:921-3. PubMed
  • Barker FG, Tatter SB. Flow-directed atrial catheter placement for ventriculoatrial shunts: technical note. Neurosurgery 1994; 35:534-5; discussion 535-6. PubMed
  • Barker FG. Efficacy of prophylactic antibiotics for craniotomy: a meta-analysis. Neurosurgery 1994; 35:484-90; discussion 491-2. PubMed
  • Barker FG. The Massachusetts General Hospital. Early history and neurosurgery to 1939. J Neurosurg 1993; 79:948-59. PubMed
  • Frim DM, Barker FG, Poletti CE, Hamilton AJ. Postoperative low-dose heparin decreases thromboembolic complications in neurosurgical patients. Neurosurgery 1992; 30:830-2; discussion 832-3. PubMed
  • Barker FG, Heros RC. Clinical aspects of vasospasm. Neurosurg Clin N Am 1990; 1:277-88. PubMed
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