My primary academic goal has been to conduct collaborative research with investigators working on biomedical research projects within and outside of the Dana-Farber/Harvard Cancer Center (DF/HCC). This research involves the design, conduct, analysis and reporting of translational clinical trials, database and laboratory studies pertaining to hematopoietic stem cell transplantation (HSCT) and cancer vaccine projects at DF/HCC, as well as leukemia-related translational clinical and laboratory studies conducted at DF/HCC. Since 2002, I have been the director of the Biostatistics Core for two NIH-funded Program Projects and the lead statistician for the Connell O’Reilly Cell Manipulation Core Facility, the Center for Human Cell Therapy and numerous federal and non-federal grants. In this capacity, I provide important biostatistical leadership for a large and diverse clinical research program in stem cell transplantation, cellular therapy, and chronic lymphocytic leukemia within the DF/HCC.
My statistical goal has been to refine analytical and reporting methods in biostatistics, mostly relating to competing risks data analysis and designs of clinical trials in hematologic malignancies. Other statistical areas of interest include time-to-event analysis, missing data analysis and analysis of genomic studies.