Photo of Helen H. Wang,  DrPH, MD

Helen H. Wang, DrPH, MD

Beth Israel Deaconess Medical Center

Beth Israel Deaconess Medical Center

Helen H. Wang, DrPH, MD

Beth Israel Deaconess Medical Center

EDUCATIONAL TITLES

  • Professor, Pathology, Harvard Medical School
  • Medical Director of Cytopathology, Pathology, Beth Israel Deaconess Medical Center

DF/HCC PROGRAM AFFILIATION

Research Abstract

My research has been in three general areas: epidemiology of chronic diseases, gastrointestinal pathology, and cytopathology. I published the first systemic epidemiology studies on lymphomatoid papulosis. My study established the close relationship and quantitated the relative risk between lymphomatoid papulosis and Hodgkin’s disease and other lymphomas. Subsequent to the case-control study, I followed these patients and showed that these lymphomatoid papulosis patients had an increased risk of developing malignancies and lymphomas. My research in GI pathology has been focused on microscopic colitis and Barrett’s-associated esophageal adenocarcinoma. My collaborations with various investigators resulted in many publications on the prognostic factors of esophageal adenocarcinoma as well as on the precursor lesions of this Barrett’s-associated adenocarcinoma. My research in cytopathology has been focused on thyroid FNA, breast FNA, gastrointestinal cytopathology and the evaluation of cost-effectiveness of different preparation and processing methods in cytology.

Publications

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  • Chao YK, Kawada K, Kumagai Y, Takubo K, Wang HH. On endocytoscopy and posttherapy pathologic staging in esophageal cancers, and on evidence-based methodology. Ann N Y Acad Sci 2014; 1325:1-7. PubMed
  • Vanderlaan PA, Wang HH, Majid A, Folch E. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA): An overview and update for the cytopathologist. Cancer Cytopathol 2014. PubMed
  • Nishino M, Wang HH. Should the thyroid AUS/FLUS category be further stratified by malignancy risk? Cancer Cytopathol 2014. PubMed
  • Star KV, Ho VT, Wang HH, Odze RD. Histologic features in colon biopsies can discriminate mycophenolate from GVHD-induced colitis. Am J Surg Pathol 2013; 37:1319-28. PubMed
  • Samedi V, White S, Zimarowski MJ, Harris A, Saffitz J, Wang HH. Metastatic peritoneal mesothelioma in the setting of recurrent ascites: A case report. Diagn Cytopathol 2010; 38:675-81. PubMed
  • Wang HH, Portincasa P, Liu M, Tso P, Samuelson LC, Wang DQ. Effect of gallbladder hypomotility on cholesterol crystallization and growth in CCK-deficient mice. Biochim Biophys Acta 2010; 1801:138-46. PubMed
  • Wang HH, Liu M, Clegg DJ, Portincasa P, Wang DQ. New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation. Biochim Biophys Acta 2009; 1791:1037-47. PubMed
  • Grattagliano I, Bonfrate L, Diogo CV, Wang HH, Wang DQ, Portincasa P. Biochemical mechanisms in drug-induced liver injury: certainties and doubts. World J Gastroenterol 2009; 15:4865-76. PubMed
  • Shields HM,Recht A,Wang HH. Exposure to Both Radiation and Chemotherapy Increases the Risk of Barrett's and Multilayered Epithelium. Dig Dis Sci 2009; 54:2143-9. PubMed
  • Peng Y,Wang HH. A meta-analysis of comparing fine-needle aspiration and frozen section for evaluating thyroid nodules. Diagn Cytopathol 2008; 36:916-20. PubMed
  • Portincasa P,Di Ciaula A,Wang HH,Palasciano G,van Erpecum KJ,Moschetta A,Wang DQ. Coordinate regulation of gallbladder motor function in the gut-liver axis. Hepatology 2008; 47:2112-26. PubMed
  • Harton AM, Wang HH, Schnitt SJ, Jacobs TW. p63 Immunocytochemistry improves accuracy of diagnosis with fine-needle aspiration of the breast. Am J Clin Pathol 2007; 128:80-5. PubMed
  • Azabdaftari G, Goldberg SN, Wang HH. Efficacy of on-site specimen adequacy evaluation of image-guided fine and core needle biopsies. Acta Cytol 2010; 54:132-7. PubMed
  • Wang HH, Myers T, Lach LJ, Hsieh CC, Kadin ME. Increased risk of lymphoid and nonlymphoid malignancies in patients with lymphomatoid papulosis. Cancer 1999; 86:1240-5. PubMed
  • Spechler SJ, Zeroogian JM, Antonioli DA, Wang HH, Goyal RK. Prevalence of metaplasia at the gastro-oesophageal junction. Lancet 1994; 344:1533-6. PubMed
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