Herman D. Suit, M.D. M.Sc. Ph.D.

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 726-8150
Fax: (617) 726-3603


Herman D. Suit, M.D. M.Sc. Ph.D.

Massachusetts General Hospital


  • Andres Soriano Professor of Radiation Oncology, Emeritus, Emeritus, Harvard Medical School
  • Chief, Radiation Oncology, Massachusetts General Hospital

Research Abstract


I. Determine the origin of the cells which form the capillary structure which supports the regrowth of tumor post radiation.

II. Understand the mechanism for the marked difference in tumor control probability following radiation treatment of chrondosarcoma and chordoma.

III. Assess the proportion of patients with distant metastasis and local regrowth of tumor whose distant metastasis arise from the regrowing tumor.

IV. Time distribution of radiation induced neoplasms as function of radiation dose and of chemotherapeutic agents.


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  • Wouters BG, Skarsgard LD, Gerweck LE, Carabe-Fernandez A, Wong M, Durand RE, Nielson D, Bussiere MR, Wagner M, Biggs P, Paganetti H, Suit HD. Radiobiological intercomparison of the 160 MeV and 230 MeV proton therapy beams at the Harvard Cyclotron Laboratory and at Massachusetts General Hospital. Radiat Res 2015; 183:174-87. PubMed
  • Devisetty K, Kobayashi W, Suit HD, Goldberg SI, Niemierko A, Chen YL, Raskin KA, Schwab JH, Springfield DS, Yoon SS, Hornicek FJ, Delaney TF. Low-Dose Neoadjuvant External Beam Radiation Therapy for Soft Tissue Sarcoma. Int J Radiat Oncol Biol Phys 2010. PubMed
  • DeLaney TF,Liebsch NJ,Pedlow FX,Adams J,Dean S,Yeap BY,McManus P,Rosenberg AE,Nielsen GP,Harmon DC,Spiro IJ,Raskin KA,Suit HD,Yoon SS,Hornicek FJ. Phase II study of high-dose photon/proton radiotherapy in the management of spine sarcomas. Int J Radiat Oncol Biol Phys 2008; 74:732-9. PubMed
  • Paganetti H, Niemierko A, Ancukiewicz M, Gerweck LE, Goitein M, Loeffler JS, Suit HD. Relative biological effectiveness (RBE) values for proton beam therapy. Int J Radiat Oncol Biol Phys 2002; 53:407-21. PubMed
  • Taghian AG, Suit HD. Animal systems for translational research in radiation oncology. Acta Oncol 1999; 38:829-38. PubMed
  • Spear MA, Jennings LC, Mankin HJ, Spiro IJ, Springfield DS, Gebhardt MC, Rosenberg AE, Efird JT, Suit HD. Individualizing management of aggressive fibromatoses. Int J Radiat Oncol Biol Phys 1998; 40:637-45. PubMed
  • Loeffler JS, Smith AR, Suit HD. The potential role of proton beams in radiation oncology. Semin Oncol 1998; 24:686-95. PubMed
  • Budach W, Gioioso D, Taghian A, Stuschke M, Suit HD. Repopulation capacity during fractionated irradiation of squamous cell carcinomas and glioblastomas in vitro. Int J Radiat Oncol Biol Phys 1997; 39:743-50. PubMed
  • Spiro IJ, Gebhardt MC, Jennings LC, Mankin HJ, Harmon DC, Suit HD. Prognostic factors for local control of sarcomas of the soft tissues managed by radiation and surgery. Semin Oncol 1997; 24:540-6. PubMed
  • Griffon-Etienne G, Boucher Y, Jain RK, Suit HD. Effects of needle insertion in tumors on interstitial fluid pressure. Microvasc Res 1997; 54:174-7. PubMed
  • Spiro IJ, Suit HD. Radiation-induced bone and soft tissue sarcomas: clinical aspects and molecular biology. Cancer Treat Res 1997; 91:143-55. PubMed
  • Taghian A, Budach W, Zietman A, Freeman J, Gioioso D, Ruka W, Suit HD. Quantitative comparison between the transplantability of human and murine tumors into the subcutaneous tissue of NCr/Sed-nu/nu nude and severe combined immunodeficient mice. Cancer Res 1993; 53:5012-7. PubMed
  • Suit H, Urie M. Proton beams in radiation therapy. J Natl Cancer Inst 1992; 84:155-64. PubMed