I-Min Lee, MD, MPH, ScD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 732-4965


ilee@rics.bwh.harvard.edu

I-Min Lee, MD, MPH, ScD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Professor, Epidemiology, Harvard T.H. Chan School Of Public Health
  • Professor, Medicine, Harvard Medical School
  • Associate Epidemiologist, Epidemiology, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

Dr. Lee's main research interest is in the role of physical activity in preventing disease (including cancer), promoting health and well-being, and enhancing longevity. She also is concerned with methodologic issues related to the assessment of physical activity. She has contributed towards the writing of the Surgeon General's report on physical activity and health, and served on the expert panel of the NIH Concensus Development Conference on Physical Acitivity and Cardiovascular Health.

Publications

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  • Arem H, Moore SC, Patel A, Hartge P, Berrington de Gonzalez A, Visvanathan K, Campbell PT, Freedman M, Weiderpass E, Adami HO, Linet MS, Lee IM, Matthews CE. Leisure Time Physical Activity and Mortality: A Detailed Pooled Analysis of the Dose-Response Relationship. JAMA Intern Med 2015. PubMed
  • Chandler PD, Buring JE, Manson JE, Giovannucci EL, Moorthy MV, Zhang S, Lee IM, Lin JH. Circulating Vitamin D Levels and Risk of Colorectal Cancer in Women. Cancer Prev Res (Phila Pa) 2015. PubMed
  • Barrdahl M, Canzian F, Lindström S, Shui I, Black A, Hoover RN, Ziegler RG, Buring JE, Chanock SJ, Diver WR, Gapstur SM, Gaudet MM, Giles GG, Haiman C, Henderson BE, Hankinson S, Hunter DJ, Joshi AD, Kraft P, Lee IM, Le Marchand L, Milne RL, Southey MC, Willett W, Gunter M, Panico S, Sund M, Weiderpass E, Sánchez MJ, Overvad K, Dossus L, Peeters PH, Khaw KT, Trichopoulos D, Kaaks R, Campa D. Association of breast cancer risk loci with breast cancer survival. Int J Cancer 2015. PubMed
  • Barrdahl M, Canzian F, Joshi AD, Travis RC, Chang-Claude J, Auer PL, Gapstur SM, Gaudet M, Diver WR, Henderson BE, Haiman CA, Schumacher FR, Le Marchand L, Berg CD, Chanock SJ, Hoover RN, Rudolph A, Ziegler RG, Giles GG, Baglietto L, Severi G, Hankinson SE, Lindström S, Willet W, Hunter DJ, Buring JE, Lee IM, Zhang S, Dossus L, Cox DG, Khaw KT, Lund E, Naccarati A, Peeters PH, Quirós JR, Riboli E, Sund M, Trichopoulos D, Prentice RL, Kraft P, Kaaks R, Campa D. Post-GWAS gene-environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79 000 women. Hum Mol Genet 2014. PubMed
  • de Rezende LF, Rabacow FM, Viscondi J YK, Luiz OC, Matsudo VK, Lee IM. Effect of Physical Inactivity on Major Non-Communicable Diseases and Life Expectancy in Brazil. J Phys Act Health 2014. PubMed
  • Poole EM, Lee IM, Ridker PM, Buring JE, Hankinson SE, Tworoger SS. A prospective study of circulating C-reactive protein, interleukin-6, and tumor necrosis factor 留 receptor 2 levels and risk of ovarian cancer. Am J Epidemiol 2013; 178:1256-64. PubMed
  • Wolpin BM, Bao Y, Qian ZR, Wu C, Kraft P, Ogino S, Stampfer MJ, Sato K, Ma J, Buring JE, Sesso HD, Lee IM, Gaziano JM, McTiernan A, Phillips LS, Cochrane BB, Pollak MN, Manson JE, Giovannucci EL, Fuchs CS. Hyperglycemia, insulin resistance, impaired pancreatic 硫-cell function, and risk of pancreatic cancer. Journal of the National Cancer Institute 2013; 105:1027-35. PubMed
  • Cook NR, Lee IM, Zhang SM, Moorthy MV, Buring JE. Alternate-day, low-dose aspirin and cancer risk: long-term observational follow-up of a randomized trial. Ann Intern Med 2013; 159:77-85. PubMed
  • Bao Y, Giovannucci EL, Kraft P, Qian ZR, Wu C, Ogino S, Gaziano JM, Stampfer MJ, Ma J, Buring JE, Sesso HD, Lee IM, Rifai N, Pollak MN, Jiao L, Lessin L, Cochrane BB, Manson JE, Fuchs CS, Wolpin BM. Inflammatory Plasma Markers and Pancreatic Cancer Risk: A Prospective Study of Five U.S. Cohorts. Cancer Epidemiol Biomarkers Prev 2013. PubMed
  • Bao Y, Giovannucci EL, Kraft P, Stampfer MJ, Ogino S, Ma J, Buring JE, Sesso HD, Lee IM, Gaziano JM, Rifai N, Pollak MN, Cochrane BB, Kaklamani V, Lin JH, Manson JE, Fuchs CS, Wolpin BM. A prospective study of plasma adiponectin and pancreatic cancer risk in five US cohorts. Journal of the National Cancer Institute 2013; 105:95-103. PubMed
  • Lee IM, Wolin KY, Freeman SE, Sattlemair J, Sesso HD. Physical Activity and Survival after Cancer Diagnosis in Men. J Phys Act Health 2012. PubMed
  • Winter AC, Rexrode KM, Lee IM, Buring JE, Tamimi RM, Kurth T. Migraine and subsequent risk of breast cancer: a prospective cohort study. Cancer Causes Control 2012. PubMed
  • Song Y, Manson JE, Lee IM, Cook NR, Paul L, Selhub J, Giovannucci E, Zhang SM. Effect of combined folic Acid, vitamin b6, and vitamin B12 on colorectal adenoma. Journal of the National Cancer Institute 2012; 104:1562-75. PubMed
  • Birmann BM, Neuhouser ML, Rosner B, Albanes D, Buring JE, Giles GG, Lan Q, Lee IM, Purdue MP, Rothman N, Severi G, Yuan JM, Anderson KC, Pollak M, Rifai N, Hartge P, Landgren O, Lessin L, Virtamo J, Wallace RB, Manson JE, Colditz GA. Pre-diagnosis biomarkers of insulin-like growth factor-1, insulin, and interleukin-6 dysregulation and multiple myeloma risk in the Multiple Myeloma Cohort Consortium. Blood 2012. PubMed
  • Siddiq A, Couch FJ, Chen GK, Lindström S, Eccles D, Millikan RC, Michailidou K, Stram DO, Beckmann L, Kyong Rhie S, Ambrosone CB, Aittomäki K, Amiano P, Apicella C, , Baglietto L, Bandera EV, Beckmann MW, Berg CD, Bernstein L, Blomqvist C, Brauch H, Brinton L, Bui QM, Buring JE, Buys SS, Campa D, Carpenter JE, Chasman DI, Chang-Claude J, Chen C, Clavel-Chapelon F, Cox A, Cross SS, Czene K, Deming SL, Diasio RB, Diver WR, Dunning AM, Durcan L, Ekici AB, Fasching PA, , Feigelson HS, Fejerman L, Figueroa JD, Fletcher O, Flesch-Janys D, Gaudet MM, , Gerty SM, Rodriguez-Gil JL, Giles GG, van Gils CH, Godwin AK, Graham N, Greco D, Hall P, Hankinson SE, Hartmann A, Hein R, Heinz J, Hoover RN, Hopper JL, Hu JJ, Huntsman S, Ingles SA, Irwanto A, Isaacs C, Jacobs KB, John EM, Justenhoven C, Kaaks R, Kolonel LN, Coetzee GA, Lathrop M, Le Marchand L, Lee AM, Lee IM, Lesnick T, Lichtner P, Liu J, Lund E, Makalic E, Martin NG, McLean CA, Meijers-Heijboer H, Meindl A, Miron P, Monroe KR, Montgomery GW, Müller-Myhsok B, Nickels S, Nyante SJ, Olswold C, Overvad K, Palli D, Park DJ, Palmer JR, Pathak H, Peto J, Pharoah P, Rahman N, Rivadeneira F, Schmidt DF, Schmutzler RK, Slager S, Southey MC, Stevens KN, Sinn HP, Press MF, Ross E, Riboli E, Ridker PM, Schumacher FR, Severi G, Dos Santos Silva I, Stone J, Sund M, Tapper WJ, Thun MJ, Travis RC, Turnbull C, Uitterlinden AG, Waisfisz Q, Wang X, Wang Z, Weaver J, Schulz-Wendtland R, Wilkens LR, Van Den Berg D, Zheng W, Ziegler RG, Ziv E, Nevanlinna H, Easton DF, Hunter DJ, Henderson BE, Chanock SJ, Garcia-Closas M, Kraft P, Haiman CA, Vachon CM. A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet 2012. PubMed
  • Hüsing A, Canzian F, Beckmann L, Garcia-Closas M, Diver WR, Thun MJ, Berg CD, Hoover RN, Ziegler RG, Figueroa JD, Isaacs C, Olsen A, Viallon V, Boeing H, Masala G, Trichopoulos D, Peeters PH, Lund E, Ardanaz E, Khaw KT, Lenner P, Kolonel LN, Stram DO, Le Marchand L, McCarty CA, Buring JE, Lee IM, Zhang S, Lindström S, Hankinson SE, Riboli E, Hunter DJ, Henderson BE, Chanock SJ, Haiman CA, Kraft P, Kaaks R, . Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status. J Med Genet 2012; 49:601-8. PubMed
  • Karageorgi S, McGrath M, Lee IM, Buring J, Kraft P, De Vivo I. Polymorphisms in genes hydroxysteroid-dehydrogenase-17b type 2 and type 4 and endometrial cancer risk. Gynecol Oncol 2011; 121:54-8. PubMed
  • Lee JE, Li H, Chan AT, Hollis BW, Lee IM, Stampfer MJ, Wu K, Giovannucci E, Ma J. Circulating levels of vitamin D and colon and rectal cancer: the Physicians' Health Study and a meta-analysis of prospective studies. Cancer Prev Res (Phila Pa) 2011. PubMed
  • McGrath M, Lee IM, Buring J, De Vivo I. Common genetic variation within IGFI, IGFII, IGFBP-1, and IGFBP-3 and endometrial cancer risk. Gynecol Oncol 2011; 120:174-8. PubMed
  • Berrington de Gonzalez A, Hartge P, Cerhan JR, Flint AJ, Hannan L, MacInnis RJ, Moore SC, Tobias GS, Anton-Culver H, Freeman LB, Beeson WL, Clipp SL, English DR, Folsom AR, Freedman DM, Giles G, Hakansson N, Henderson KD, Hoffman-Bolton J, Hoppin JA, Koenig KL, Lee IM, Linet MS, Park Y, Pocobelli G, Schatzkin A, Sesso HD, Weiderpass E, Willcox BJ, Wolk A, Zeleniuch-Jacquotte A, Willett WC, Thun MJ. Body-mass index and mortality among 1.46 million white adults. N Engl J Med 2010; 363:2211-9. PubMed
  • Gu F, Schumacher FR, Canzian F, Allen NE, Albanes D, Berg CD, Berndt SI, Boeing H, Bueno-de-Mesquita HB, Buring JE, Chabbert-Buffet N, Chanock SJ, Clavel-Chapelon F, Dumeaux V, Gaziano JM, Giovannucci EL, Haiman CA, Hankinson SE, Hayes RB, Henderson BE, Hunter DJ, Hoover RN, Johansson M, Key TJ, Khaw KT, Kolonel LN, Lagiou P, Lee IM, Lemarchand L, Lund E, Ma J, Onland-Moret NC, Overvad K, Rodriguez L, Sacerdote C, Sánchez MJ, Stampfer MJ, Stattin P, Stram DO, Thomas G, Thun MJ, Tjønneland A, Trichopoulos D, Tumino R, Virtamo J, Weinstein SJ, Willett WC, Yeager M, Zhang SM, Kaaks R, Riboli E, Ziegler RG, Kraft P. Eighteen Insulin-like Growth Factor Pathway Genes, Circulating Levels of IGF-I and its Binding Protein, and Risk of Prostate and Breast Cancer. Cancer Epidemiol Biomarkers Prev 2010; 19:2877-87. PubMed
  • Prescott J, McGrath M, Lee IM, Buring JE, De Vivo I. Telomere length and genetic analyses in population-based studies of endometrial cancer risk. Cancer 2010; 116:4275-82. PubMed
  • Sawada SS, Lee IM, Naito H, Tsukamoto K, Muto T, Blair SN. Muscular and performance fitness and the incidence of type 2 diabetes: prospective study of Japanese men. J Phys Act Health 2010; 7:627-32. PubMed
  • Byun W, Sui X, Hébert JR, Church TS, Lee IM, Matthews CE, Blair SN. Cardiorespiratory fitness and risk of prostate cancer: Findings from the Aerobics Center Longitudinal Study. 2010. PubMed
  • Sawada SS, Lee IM, Naito H, Noguchi J, Tsukamoto K, Muto T, Higaki Y, Tanaka H, Blair SN. Long-term trends in cardiorespiratory fitness and the incidence of type 2 diabetes. Diabetes Care 2010; 33:1353-7. PubMed
  • Lin J, Zee RY, Liu KY, Zhang SM, Lee IM, Manson JE, Giovannucci E, Buring JE, Cook NR. Genetic variation in sex-steroid receptors and synthesizing enzymes and colorectal cancer risk in women. Cancer Causes Control 2010; 21:897-908. PubMed
  • Terry K, McGrath M, Lee IM, Buring J, De Vivo I. Genetic variation in CYP11A1 and StAR in relation to endometrial cancer risk. Gynecol Oncol 2010; 117:255-9. PubMed
  • Lin J, Lee IM, Song Y, Cook NR, Selhub J, Manson JE, Buring JE, Zhang SM. Plasma homocysteine and cysteine and risk of breast cancer in women. Cancer Res 2010; 70:2397-405. PubMed
  • Lee IM, Lin J, Castonguay AJ, Barton NS, Buring JE, Zee RY. Mean leukocyte telomere length and risk of incident colorectal carcinoma in women: a prospective, nested case-control study. Clin. Chem. Lab. Med. 2010; 48:259-62. PubMed
  • Conroy MB,Sattelmair JR,Cook NR,Manson JE,Buring JE,Lee IM. Physical activity, adiposity, and risk of endometrial cancer. Cancer Causes Control 2009; 20:1107-15. PubMed
  • Thomas G,Jacobs KB,Kraft P,Yeager M,Wacholder S,Cox DG,Hankinson SE,Hutchinson A,Wang Z,Yu K,Chatterjee N,Garcia-Closas M,Gonzalez-Bosquet J,Prokunina-Olsson L,Orr N,Willett WC,Colditz GA,Ziegler RG,Berg CD,Buys SS,McCarty CA,Feigelson HS,Calle EE,Thun MJ,Diver R,Prentice R,Jackson R,Kooperberg C,Chlebowski R,Lissowska J,Peplonska B,Brinton LA,Sigurdson A,Doody M,Bhatti P,Alexander BH,Buring J,Lee IM,Vatten LJ,Hveem K,Kumle M,Hayes RB,Tucker M,Gerhard DS,Fraumeni JF Jr,Hoover RN,Chanock SJ,Hunter DJ. A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet 2009; 41:579-84. PubMed
  • Lee JE,Li H,Giovannucci E,Lee IM,Selhub J,Stampfer M,Ma J. Prospective study of plasma vitamin B6 and risk of colorectal cancer in men. Cancer Epidemiol Biomarkers Prev 2009; 18:1197-202. PubMed
  • Karlson EW,Chibnik LB,Tworoger SS,Lee IM,Buring JE,Shadick NA,Manson JE,Costenbader KH. Biomarkers of inflammation and development of rheumatoid arthritis in women from two prospective cohort studies. Arthritis Rheum 2009; 60:641-52. PubMed
  • McGrath M,Lepine J,Lee IM,Villeneuve L,Buring J,Guillemette C,De Vivo I. Genetic variations in UGT1A1 and UGT2B7 and endometrial cancer risk. Pharmacogenet Genomics 2009; 19:239-43. PubMed
  • Wang L,Lee IM,Zhang SM,Blumberg JB,Buring JE,Sesso HD. Dietary intake of selected flavonols, flavones, and flavonoid-rich foods and risk of cancer in middle-aged and older women. Am J Clin Nutr 2009; 89:905-12. PubMed
  • Tworoger SS,Gate MA,Lee IM,Buring JE,Titus-Ernstoff L,Cramer D,Hankinson SE. Polymorphisms in the vitamin D receptor and risk of ovarian cancer in four studies. Cancer Res 2009; 69:1885-91. PubMed
  • Karlson EW, Chibnik LB, McGrath M, Chang SC, Keenan BT, Costenbader KH, Fraser PA, Tworoger S, Hankinson SE, Lee IM, Buring J, De Vivo I. A prospective study of androgen levels, hormone-related genes and risk of rheumatoid arthritis. Arthritis Res Ther 2009; 11:R97. PubMed
  • McGrath M,Lee IM,Buring J,Hunter DJ,De Vivo I. Novel breast cancer risk alleles and endometrial cancer risk. Int J Cancer 2008; 123:2961-4. PubMed
  • Roux L,Pratt M,Tengs TO,Yore MM,Yanagawa TL,Van Den Bos J,Rutt C,Brownson RC,Powell KE,Heath G,Kohl HW 3rd,Teutsch S,Cawley J,Lee IM,West L,Buchner DM. Cost effectiveness of community-based physical activity interventions. Am J Prev Med 2008; 35:578-88. PubMed
  • Crespo CJ,Garcia-Palmieri MR,Smit E,Lee IM,McGee D,Muti P,Figueroa Valle NR,Ramierez-Marrero FA,Freudenheim JL,Sorlie P. Physical activity and prostate cancer mortality in Puerto Rican men. J Phys Act Health 2009; 5:918-29. PubMed
  • Thun MJ,Hannan LM,Adams-Campbell LL,Boffetta P,Buring JE,Feskanich D,Flanders WD,Jee SH,Katanoda K,Kolonel LN,Lee IM,Marugame T,Palmer JR,Riboli E,Sobue T,Avila-Tang E,Wilkens LR,Samet JM. Lung cancer occurrence in never-smokers: an analysis of 13 cohorts and 22 cancer registry studies. PLoS Med 2008; 5:e185. PubMed
  • Terry K, McGrath M, Lee IM, Buring J, De Vivo I. MDM2 SNP309 Is Associated with Endometrial Cancer Risk. Cancer Epidemiol Biomarkers Prev 2008; 17:983-6. PubMed
  • Zhang SM, Cook NR, Manson JE, Lee IM, Buring JE. Low-dose aspirin and breast cancer risk: results by tumour characteristics from a randomised trial. Br J Cancer 2008; 98:989-91. PubMed
  • Sui X, Hooker SP, Lee IM, Church TS, Colabianchi N, Lee CD, Blair SN. A Prospective Study of Cardiorespiratory Fitness and Risk of Type 2 Diabetes in Women. Diabetes Care 2008; 31:550-5. PubMed
  • Lin J, Lee IM, Cook NR, Selhub J, Manson JE, Buring JE, Zhang SM. Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women. Am J Clin Nutr 2008; 87:734-43. PubMed
  • Tworoger SS, Lee IM, Buring JE, Hankinson SE. Plasma androgen concentrations and risk of incident ovarian cancer. Am J Epidemiol 2007; 167:211-8. PubMed
  • Wolin KY, Lee IM, Colditz GA, Glynn RJ, Fuchs C, Giovannucci E. Leisure-time physical activity patterns and risk of colon cancer in women. Int J Cancer 2007; 121:2776-81. PubMed
  • Logroscino G, Sesso HD, Paffenbarger RS, Lee IM. Body mass index and risk of Parkinson's disease: a prospective cohort study. Am J Epidemiol 2007; 166:1186-90. PubMed
  • Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA, Macera CA, Heath GW, Thompson PD, Bauman A, ,. Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation 2007; 116:1081-93. PubMed
  • Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA, Macera CA, Heath GW, Thompson PD, Bauman A. Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc 2007; 39:1423-34. PubMed
  • Tworoger SS, Lee IM, Buring JE, Pollak MN, Hankinson SE. Insulin-like growth factors and ovarian cancer risk: a nested case-control study in three cohorts. Cancer Epidemiol Biomarkers Prev 2007; 16:1691-5. PubMed
  • Zhang SM, Lin J, Cook NR, Lee IM, Manson JE, Buring JE, Ridker PM. C-reactive protein and risk of breast cancer. Journal of the National Cancer Institute 2007; 99:890-4. PubMed
  • Wolin KY, Glynn RJ, Colditz GA, Lee IM, Kawachi I. Long-term physical activity patterns and health-related quality of life in u.s. Women. Am J Prev Med 2007; 32:490-9. PubMed
  • Lin J, Manson JE, Lee IM, Cook NR, Buring JE, Zhang SM. Intakes of calcium and vitamin d and breast cancer risk in women. Arch Intern Med 2007; 167:1050-9. PubMed
  • Lee IM. Dose-response relation between physical activity and fitness: even a little is good; more is better. JAMA 2007; 297:2137-9. PubMed
  • Lin J, Zhang SM, Cook NR, Manson JE, Buring JE, Lee IM. Oral contraceptives, reproductive factors, and risk of colorectal cancer among women in a prospective cohort study. Am J Epidemiol 2007; 165:794-801. PubMed
  • Tworoger SS, Lee IM, Buring JE, Rosner B, Hollis BW, Hankinson SE. Plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D and risk of incident ovarian cancer. Cancer Epidemiol Biomarkers Prev 2007; 16:783-8. PubMed
  • Zhang SM, Lee IM, Manson JE, Cook NR, Willett WC, Buring JE. Alcohol consumption and breast cancer risk in the Women's Health Study. Am J Epidemiol 2007; 165:667-76. PubMed
  • Zhang SM, Manson JE, Rexrode KM, Cook NR, Buring JE, Lee IM. Use of oral conjugated estrogen alone and risk of breast cancer. Am J Epidemiol 2006; 165:524-9. PubMed
  • Driver JA, Gaziano JM, Gelber RP, Lee IM, Buring JE, Kurth T. Development of a risk score for colorectal cancer in men. Am J Med 2007; 120:257-63. PubMed
  • Koh KA, Sesso HD, Paffenbarger RS, Lee IM. Dairy products, calcium and prostate cancer risk. Br J Cancer 2006; 95:1582-5. PubMed
  • Logroscino G, Sesso HD, Paffenbarger RS, Lee IM. Physical activity and risk of Parkinson's disease: a prospective cohort study. J Neurol Neurosurg Psychiatry 2006; 77:1318-22. PubMed
  • St. Metabolic abnormalities and risk for colorectal cancer in the physicians' health study. Cancer Epidemiol Biomarkers Prev 2006; 15:2391-7. PubMed
  • Shadick NA, Cook NR, Karlson EW, Ridker PM, Maher NE, Manson JE, Buring JE, Lee IM. C-reactive protein in the prediction of rheumatoid arthritis in women. Arch Intern Med 2006; 166:2490-4. PubMed
  • Liu S, Lee IM, Song Y, Van Denburgh M, Cook NR, Manson JE, Buring JE. Vitamin E and risk of type 2 diabetes in the women's health study randomized controlled trial. Diabetes 2006; 55:2856-62. PubMed
  • Lin J, Cook NR, Lee IM, Manson JE, Buring JE, Zhang SM. Total magnesium intake and colorectal cancer incidence in women. Cancer Epidemiol Biomarkers Prev 2006; 15:2006-9. PubMed
  • St. Colorectal cancer after start of nonsteroidal anti-inflammatory drug use. Am J Med 2006; 119:494-502. PubMed
  • Mora S, Lee IM, Buring JE, Ridker PM. Association of physical activity and body mass index with novel and traditional cardiovascular biomarkers in women. JAMA 2006; 295:1412-9. PubMed
  • Lin J, Ridker PM, Rifai N, Lee IM, Manson JE, Buring JE, Zhang SM. A prospective study of hemoglobin A1c concentrations and risk of breast cancer in women. Cancer Res 2006; 66:2869-75. PubMed
  • Lee IM, Gaziano JM, Buring JE. Vitamin E in the prevention of prostate cancer: where are we today? J Natl Cancer Inst 2006; 98:225-7. PubMed
  • Zhang SM, Moore SC, Lin J, Cook NR, Manson JE, Lee IM, Buring JE. Folate, vitamin B6, multivitamin supplements, and colorectal cancer risk in women. Am J Epidemiol 2005; 163:108-15. PubMed
  • Lin J, Ridker PM, Pradhan A, Lee IM, Manson JE, Cook NR, Buring JE, Zhang SM. Hemoglobin A1c concentrations and risk of colorectal cancer in women. Cancer Epidemiol Biomarkers Prev 2005; 14:3010-2. PubMed
  • Cook NR, Lee IM, Gaziano JM, Gordon D, Ridker PM, Manson JE, Hennekens CH, Buring JE. Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial. JAMA 2005; 294:47-55. PubMed
  • Lee IM, Cook NR, Gaziano JM, Gordon D, Ridker PM, Manson JE, Hennekens CH, Buring JE. Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial. JAMA 2005; 294:56-65. PubMed
  • Oguma Y, Sesso HD, Paffenbarger RS, Lee IM. Weight change and risk of developing type 2 diabetes. Obes Res 2005; 13:945-51. PubMed
  • Lin J, Zhang SM, Cook NR, Manson JE, Lee IM, Buring JE. Intakes of calcium and vitamin D and risk of colorectal cancer in women. Am J Epidemiol 2005; 161:755-64. PubMed
  • Lin J, Zhang SM, Cook NR, Rexrode KM, Liu S, Manson JE, Lee IM, Buring JE. Dietary intakes of fruit, vegetables, and fiber, and risk of colorectal cancer in a prospective cohort of women (United States). Cancer Causes Control 2005; 16:225-33. PubMed
  • Zhang SM, Buring JE, Lee IM, Cook NR, Ridker PM. C-reactive protein levels are not associated with increased risk for colorectal cancer in women. Ann Intern Med 2005; 142:425-32. PubMed
  • Lee IM, Sesso HD, Oguma Y, Paffenbarger RS. The "weekend warrior" and risk of mortality. Am J Epidemiol 2004; 160:636-41. PubMed
  • Lee IM. Physical activity in women: how much is good enough? JAMA 2003; 290:1377-9. PubMed
  • Lee IM, Rexrode KM, Cook NR, Manson JE, Buring JE. Physical activity and coronary heart disease in women: is "no pain, no gain" pass蘓 JAMA 2001; 285:1447-54. PubMed
  • Tworoger SS, Lee IM, Buring JE, Rosner B, Hollis BW, Hankinson SE. Plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D and risk of incident ovarian cancer. CA Cancer J Clin 2007; 16:783-8.
  • Lee IM, Cook NR, Manson JE, Buring JE, Hennekens CH. Beta-carotene supplementation and incidence of cancer and cardiovascular disease: the Women's Health Study. J Natl Cancer Inst 1999; 91:2102-6. PubMed
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