I am the Principal Investigator for the Dana-Farber/Harvard SPORE in Breast Cancer. I led the Women's Cancers Program at Dana-Farber and Co-lead the Breast Cancer Program in the Cancer Center. My own research focuses on breast cancer genetics and genomics, and on translational cancer research in general. Current projects include the role of NF-kB signaling in breast cancer, the role of DNA damage pathways in certain breast and ovarian cancers, BRCA1 and BRCA2 susceptibility genes, and copy number alterations in breast and ovarian cancer. This work is carried out by several investigators in the Women's Cancers Program at Dana-Farber.