Photo of Johannes Walter,  PhD

Johannes Walter, PhD

Harvard Medical School

Harvard Medical School
Phone: (617) 432-4799
Fax: (617) 738-0516


johannes_walter@hms.harvard.edu

Johannes Walter, PhD

Harvard Medical School

EDUCATIONAL TITLES

  • Professor, Biological Chemistry and Molecular Pharmacology, Harvard Medical School

DF/HCC PROGRAM AFFILIATION

Publications

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  • Dewar JM, Walter JC. Mechanisms of DNA replication termination. Nat Rev Mol Cell Biol 2017. PubMed
  • Dewar JM, Low E, Mann M, Räschle M, Walter JC. CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication termination. Genes Dev 2017; 31:275-290. PubMed
  • Graham TGW, Walter JC, Loparo JJ. Ensemble and Single-Molecule Analysis of Non-Homologous End Joining in Frog Egg Extracts. Methods Enzymol 2017; 591:233-270. PubMed
  • Semlow DR, Zhang J, Budzowska M, Drohat AC, Walter JC. Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase. Cell 2016; 167:498-511.e14. PubMed
  • Graham TG, Walter JC, Loparo JJ. Two-Stage Synapsis of DNA Ends during Non-homologous End Joining. Mol Cell 2016; 61:850-8. PubMed
  • Joukov V, Walter JC, De Nicolo A. Assays to Study Mitotic Centrosome and Spindle Pole Assembly and Regulation. Methods Mol Biol 2016; 1413:207-35. PubMed
  • Duxin JP, Walter JC. What is the DNA repair defect underlying Fanconi anemia? Curr Opin Cell Biol 2015; 37:49-60. PubMed
  • Dewar JM, Budzowska M, Walter JC. The mechanism of DNA replication termination in vertebrates. Nature 2015; 525:345-50. PubMed
  • Budzowska M, Graham TG, Sobeck A, Waga S, Walter JC. Regulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link. EMBO J 2015; 34:1971-85. PubMed
  • Räschle M, Smeenk G, Hansen RK, Temu T, Oka Y, Hein MY, Nagaraj N, Long DT, Walter JC, Hofmann K, Storchova Z, Cox J, Bekker-Jensen S, Mailand N, Mann M. DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links. Science 2015; 348:1253671. PubMed
  • Chistol G, Walter JC. Single-Molecule Visualization of MCM2-7 DNA Loading: Seeing Is Believing. Cell 2015; 161:429-30. PubMed
  • Zhang J, Dewar JM, Budzowska M, Motnenko A, Cohn MA, Walter JC. DNA interstrand cross-link repair requires replication-fork convergence. Nat Struct Mol Biol 2015; 22:242-7. PubMed
  • Duxin JP, Dewar JM, Yardimci H, Walter JC. Repair of a DNA-protein crosslink by replication-coupled proteolysis. Cell 2014; 159:346-57. PubMed
  • Long DT, Joukov V, Budzowska M, Walter JC. BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork. Mol Cell 2014; 56:174-85. PubMed
  • Long DT, Räschle M, Joukov V, Walter JC. Mechanism of RAD51-dependent DNA interstrand cross-link repair. Science 2011; 333:84-7. PubMed
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