Photo of John J. Godleski,  MD

John J. Godleski, MD

Harvard T.H. Chan School Of Public Health

Harvard T.H. Chan School Of Public Health
Phone: (617) 432-1252


jgodlesk@hsph.harvard.edu

John J. Godleski, MD

Harvard T.H. Chan School Of Public Health

EDUCATIONAL TITLES

  • Associate Professor, Environmental Health, Harvard T.H. Chan School Of Public Health
  • Associate Professor, Pathology, Harvard Medical School

DF/HCC PROGRAM AFFILIATION

Research Abstract

As pulmonary pathologist at BWH, I have interest in pathologic diagnosis of thoracic malignancies including lung cancer, mesothelioma, and mediastinal malignancies. I also have interest in the operation and use of tissue repositories for research.

Publications

Powered by Harvard Catalyst
  • Chirieac LR, Barletta JA, Yeap BY, Richards WG, Tilleman T, Bueno R, Baldini EH, Godleski J, Sugarbaker DJ. Clinicopathologic characteristics of malignant mesotheliomas arising in patients with a history of radiation for Hodgkin and non-Hodgkin lymphoma. J Clin Oncol 2013; 31:4544-9. PubMed
  • Sugarbaker DJ, Wolf AS, Chirieac LR, Godleski JJ, Tilleman TR, Jaklitsch MT, Bueno R, Richards WG. Clinical and pathological features of three-year survivors of malignant pleural mesothelioma following extrapleural pneumonectomy. 2011. PubMed
  • Christensen BC, Houseman EA, Poage GM, Godleski JJ, Bueno R, Sugarbaker DJ, Wiencke JK, Nelson HH, Marsit CJ, Kelsey KT. Integrated profiling reveals a global correlation between epigenetic and genetic alterations in mesothelioma. Cancer Res 2010; 70:5686-94. PubMed
  • Clougherty JE, Rossi CA, Lawrence J, Long MD, Diaz EA, Lim R, McEwen B, Koutrakis P, Godleski JJ. Chronic Social Stress and Susceptibility to Concentrated Ambient Fine Particles in Rats. Environ Health Perspect 2010; 118:769-75. PubMed
  • Richards WG, Godleski JJ, Yeap BY, Corson JM, Chirieac LR, Zellos L, Mujoomdar A, Jaklitsch MT, Bueno R, Sugarbaker DJ. Proposed adjustments to pathologic staging of epithelial malignant pleural mesothelioma based on analysis of 354 cases. Cancer 2010; 116:1510-7. PubMed
  • Bartoli CR, Godleski JJ. Blood Flow in the Foreign-Body Capsules Surrounding Surgically Implanted Subcutaneous Devices. J Surg Res 2009; 158:147-54. PubMed
  • Christensen BC, Marsit CJ, Houseman EA, Godleski JJ, Longacker JL, Zheng S, Yeh RF, Wrensch MR, Wiemels JL, Karagas MR, Bueno R, Sugarbaker DJ, Nelson HH, Wiencke JK, Kelsey KT. Differentiation of lung adenocarcinoma, pleural mesothelioma, and nonmalignant pulmonary tissues using DNA methylation profiles. Cancer Res 2009; 69:6315-21. PubMed
  • Christensen BC,Houseman EA,Godleski JJ,Marsit CJ,Longacker JL,Roelofs CR,Karagas MR,Wrensch MR,Yeh RF,Nelson HH,Wiemels JL,Zheng S,Wiencke JK,Bueno R,Sugarbaker DJ,Kelsey KT. Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome. Cancer Res 2009; 69:227-34. PubMed
  • Christensen BC, Godleski JJ, Marsit CJ, Houseman EA, Lopez-Fagundo CY, Longacker JL, Bueno R, Sugarbaker DJ, Nelson HH, Kelsey KT. Asbestos exposure predicts cell cycle control gene promoter methylation in pleural mesothelioma. Carcinogenesis 2008; 29:1555-9. PubMed
  • Christensen BC, Godleski JJ, Roelofs CR, Longacker JL, Bueno R, Sugarbaker DJ, Marsit CJ, Nelson HH, Kelsey KT. Asbestos burden predicts survival in pleural mesothelioma. Environ Health Perspect 2008; 116:723-6. PubMed
  • Bartoli CR, Okabe K, Akiyama I, Coull B, Godleski JJ. Repeat microsphere delivery for serial measurement of regional blood perfusion in the chronically instrumented, conscious canine. J Surg Res 2007; 145:135-41. PubMed
  • Bartoli CR, Akiyama I, Okabe K, Diaz EA, Godleski JJ. Permanent tracheostomy for long-term respiratory studies. J Surg Res 2007; 145:124-9. PubMed
  • Bartoli CR, Akiyama I, Godleski JJ, Verrier RL. Long-term pericardial catheterization is associated with minimum foreign-body response. Catheter Cardiovasc Interv 2007; 70:221-7. PubMed
  • Cramer DW, Welch WR, Berkowitz RS, Godleski JJ. Presence of talc in pelvic lymph nodes of a woman with ovarian cancer and long-term genital exposure to cosmetic talc. Obstet Gynecol 2007; 110:498-501. PubMed
  • Nikolov MC,Coull BA,Catalano PJ,Godleski JJ. An informative Bayesian structural equation model to assess source-specific health effects of air pollution. Biostatistics 2006; 8:609-24. PubMed
  • Wellenius GA, Coull BA, Batalha JR, Diaz EA, Lawrence J, Godleski JJ. Effects of ambient particles and carbon monoxide on supraventricular arrhythmias in a rat model of myocardial infarction. Inhal Toxicol 2006; 18:1077-82. PubMed
  • Bartoli CR, Okabe K, Akiyama I, Verrier RL, Godleski JJ. Technique for implantation of chronic indwelling aortic access catheters. J Invest Surg 2006; 19:397-405. PubMed
  • Hatzis C, Godleski JJ, Gonz. Ambient particulate matter exhibits direct inhibitory effects on oxidative stress enzymes. Environ Sci Technol 2006; 40:2805-11. PubMed
  • Kraunz KS, Nelson HH, Lemos M, Godleski JJ, Wiencke JK, Kelsey KT. Homozygous deletion of p16(INK4a) and tobacco carcinogen exposure in nonsmall cell lung cancer. Int J Cancer 2005; 118:1364-9. PubMed
  • Godleski JJ. Responses of the heart to ambient particle inhalation. Clin Occup Environ Med 2006; 5:849-64. PubMed
  • Morrison PR, vanSonnenberg E, Shankar S, Godleski J, Silverman SG, Tuncali K, Jaklitsch MT, Jolesz FA. Radiofrequency ablation of thoracic lesions: part 1, experiments in the normal porcine thorax. AJR Am J Roentgenol 2005; 184:375-80. PubMed
  • Godleski JJ. Role of asbestos in etiology of malignant pleural mesothelioma. Thorac Surg Clin 2004; 14:479-87. PubMed
  • Wellenius GA, Batalha JR, Diaz EA, Lawrence J, Coull BA, Katz T, Verrier RL, Godleski JJ. Cardiac effects of carbon monoxide and ambient particles in a rat model of myocardial infarction. Toxicol Sci 2004; 80:367-76. PubMed
  • Rhoden CR, Lawrence J, Godleski JJ, Gonz. N-acetylcysteine prevents lung inflammation after short-term inhalation exposure to concentrated ambient particles. Toxicol Sci 2004; 79:296-303. PubMed
  • Medeiros N, Rivero DH, Kasahara DI, Saiki M, Godleski JJ, Koutrakis P, Capelozzi VL, Saldiva PH, Antonangelo L. Acute pulmonary and hematological effects of two types of particle surrogates are influenced by their elemental composition. Environ Res 2004; 95:62-70. PubMed
  • Pope CA, Burnett RT, Thurston GD, Thun MJ, Calle EE, Krewski D, Godleski JJ. Cardiovascular Mortality and Long-Term Exposure to Particulate Air Pollution. Epidemiological Evidence of General Pathophysiological Pathways of Disease. Circulation 2004; 109:71-7. PubMed
  • Wellenius GA, Coull BA, Godleski JJ, Koutrakis P, Okabe K, Savage ST, Lawrence JE, Murthy GG, Verrier RL. Inhalation of concentrated ambient air particles exacerbates myocardial ischemia in conscious dogs. Environ Health Perspect 2003; 111:402-8. PubMed
  • Batalha JR, Saldiva PH, Clarke RW, Coull BA, Stearns RC, Lawrence J, Murthy GG, Koutrakis P, Godleski JJ. Concentrated ambient air particles induce vasoconstriction of small pulmonary arteries in rats. Environ Health Perspect 2002; 110:1191-7. PubMed
  • Saldiva PH, Clarke RW, Coull BA, Stearns RC, Lawrence J, Murthy GG, Diaz E, Koutrakis P, Suh H, Tsuda A, Godleski JJ. Lung inflammation induced by concentrated ambient air particles is related to particle composition. Am J Respir Crit Care Med 2002; 165:1610-7. PubMed
  • Hauser R, Godleski JJ, Hatch V, Christiani DC. Ultrafine particles in human lung macrophages. Arch Environ Health 2001; 56:150-6. PubMed
  • Stearns RC, Paulauskis JD, Godleski JJ. Endocytosis of ultrafine particles by A549 cells. Am J Respir Cell Mol Biol 2001; 24:108-15. PubMed
  • Breathnach OS, Kwiatkowski DJ, Finkelstein DM, Godleski J, Sugarbaker DJ, Johnson BE, Mentzer S. Bronchioloalveolar carcinoma of the lung: recurrences and survival in patients with stage I disease. J Thorac Cardiovasc Surg 2001; 121:42-7. PubMed
  • Shieh DB, Godleski J, Herndon JE, Azuma T, Mercer H, Sugarbaker DJ, Kwiatkowski DJ. Cell motility as a prognostic factor in Stage I nonsmall cell lung carcinoma: the role of gelsolin expression. Cancer 1999; 85:47-57. PubMed
  • Kwiatkowski DJ, Harpole DH, Godleski J, Herndon JE, Shieh DB, Richards W, Blanco R, Xu HJ, Strauss GM, Sugarbaker DJ. Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: clinical implications. J Clin Oncol 1998; 16:2468-77. PubMed
  • Shapiro GI, Edwards CD, Kobzik L, Godleski J, Richards W, Sugarbaker DJ, Rollins BJ. Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines. Cancer Res 1995; 55:505-9. PubMed
Hide