Photo of Leonid Mirny,  PhD

Leonid Mirny, PhD

Massachusetts Institute of Technology

Massachusetts Institute of Technology
Phone: (617) 452-4862


leonid@mit.edu

Leonid Mirny, PhD

Massachusetts Institute of Technology

EDUCATIONAL TITLES

  • Associate Professor, Heath, Sciences and Technology, Massachusetts Institute of Technology
  • Associate Professor, with tenure, of Health Sciences and Technology, and Physics, MIT, Harvard-MIT Division of Health, Sciences and Technology, Massachusetts Institute of Technology

DF/HCC PROGRAM AFFILIATION

Publications

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  • Imakaev MV, Tchourine KM, Nechaev SK, Mirny LA. Effects of topological constraints on globular polymers. Soft Matter 2014; 11:665-71. PubMed
  • McFarland CD, Mirny LA, Korolev KS. Tug-of-war between driver and passenger mutations in cancer and other adaptive processes. Proc Natl Acad Sci U S A 2014; 111:15138-43. PubMed
  • Mizuguchi T, Fudenberg G, Mehta S, Belton JM, Taneja N, Folco HD, FitzGerald P, Dekker J, Mirny L, Barrowman J, Grewal SI. Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe. Nature 2014. PubMed
  • Doyle B, Fudenberg G, Imakaev M, Mirny LA. Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions. PLoS Comput. Biol. 2014; 10:e1003867. PubMed
  • Yaglom JA, McFarland C, Mirny L, Sherman MY. Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer. 2014; 5:8367-78. PubMed
  • Naumova N, Imakaev M, Fudenberg G, Zhan Y, Lajoie BR, Mirny LA, Dekker J. Organization of the mitotic chromosome. Science 2013; 342:948-53. PubMed
  • Le TB, Imakaev MV, Mirny LA, Laub MT. High-resolution mapping of the spatial organization of a bacterial chromosome. Science 2013; 342:731-4. PubMed
  • Dekker J, Marti-Renom MA, Mirny LA. Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data. Nat Rev Genet 2013. PubMed
  • McFarland CD, Korolev KS, Kryukov GV, Sunyaev SR, Mirny LA. Impact of deleterious passenger mutations on cancer progression. Proc Natl Acad Sci U S A 2013; 110:2910-5. PubMed
  • Imakaev M, Fudenberg G, McCord RP, Naumova N, Goloborodko A, Lajoie BR, Dekker J, Mirny LA. Iterative correction of Hi-C data reveals hallmarks of chromosome organization. Nat Methods 2012; 9:999-1003. PubMed