Photo of Linda S. Huang,  PhD

Linda S. Huang, PhD

University Of Massachusetts - Boston

University Of Massachusetts - Boston
Phone: (617) 287-6674
Fax: (617) 287-6650


linda.huang@umb.edu

Linda S. Huang, PhD

University Of Massachusetts - Boston

EDUCATIONAL TITLES

  • Associate Professor, College of Science and Math, University Of Massachusetts - Boston
  • Associate Member, Cancer Biology, Dana-Farber Cancer Institute

DF/HCC PROGRAM AFFILIATION

Research Abstract

My laboratory uses the budding yeast Saccharomyces cerevisiae to understand basic aspects of cell biology. We are interested in understanding how cell shape and architecture are regulated. The research in my lab focuses on the process of sporulation, which is the yeast cell’s version of gametogenesis and involves meiosis followed by spore morphogenesis. Research projects in the lab include studies on how the PH-domain containing protein Spo71 regulates membrane shape and size and how the MAP kinase Smk1 and the PAK-family GCKIII kinase Sps1 regulate spore morphogenesis.

Publications

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  • Parodi EM, Baker CS, Tetzlaff C, Villahermosa S, Huang LS. SPO71 mediates prospore membrane size and maturation in Saccharomyces cerevisiae. Eukaryot Cell 2012; 11:1191-200. PubMed
  • Davison EM, Saffer AM, Huang LS, DeModena J, Sternberg PW, Horvitz HR. The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination. Genetics 2011; 187:803-15. PubMed
  • Auld KL, Hitchcock AL, Doherty HK, Frietze S, Huang LS, Silver PA. The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae. Genetics 2006; 174:215-27. PubMed