Photo of Mark W. Feinberg,  MD

Mark W. Feinberg, MD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 525-4381


mfeinberg@partners.org

Mark W. Feinberg, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Associate Professor, Medicine, Harvard Medical School

DF/HCC PROGRAM AFFILIATION

Publications

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  • Feinberg MW. Fine-tuning innate and adaptive immune responses: another KLFhanger. Focus on "Kr端ppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-硫 signaling in CD8+ T lymphocytes". Am J Physiol Cell Physiol 2015; 308:C359-61. PubMed
  • Khedkar SA, Sun X, Rigby AC, Feinberg MW. Discovery of small molecule inhibitors to Kr端ppel-like factor 10 (KLF10): implications for modulation of T regulatory cell differentiation. J Med Chem 2015; 58:1466-78. PubMed
  • Icli B, Wara AK, Moslehi J, Sun X, Plovie E, Cahill M, Marchini JF, Schissler A, Padera RF, Shi J, Cheng HW, Raghuram S, Arany Z, Liao R, Croce K, MacRae C, Feinberg MW. MicroRNA-26a regulates pathological and physiological angiogenesis by targeting BMP/SMAD1 signaling. Circ Res 2013; 113:1231-41. PubMed
  • Wara AK, Manica A, Marchini JF, Sun X, Icli B, Tesmenitsky Y, Croce K, Feinberg MW. Bone marrow-derived Kruppel-like factor 10 controls reendothelialization in response to arterial injury. Arterioscler Thromb Vasc Biol 2013; 33:1552-60. PubMed
  • Cao Z, Sun X, Icli B, Wara AK, Feinberg MW. Role of Kruppel-like factors in leukocyte development, function, and disease. Blood 2010; 116:4404-14. PubMed
  • Cao Z, Wara AK, Icli B, Sun X, Packard RR, Esen F, Stapleton CJ, Subramaniam M, Kretschmer K, Apostolou I, von Boehmer H, Hansson GK, Spelsberg TC, Libby P, Feinberg MW. Kruppel-like factor KLF10 targets transforming growth factor-beta1 to regulate CD4(+)CD25(-) T cells and T regulatory cells. J Biol Chem 2009; 284:24914-24. PubMed
  • Feinberg MW, Wara AK, Cao Z, Lebedeva MA, Rosenbauer F, Iwasaki H, Hirai H, Katz JP, Haspel RL, Gray S, Akashi K, Segre J, Kaestner KH, Tenen DG, Jain MK. The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation. EMBO J 2007; 26:4138-48. PubMed
  • Feinberg MW, Cao Z, Wara AK, Lebedeva MA, Senbanerjee S, Jain MK. Kruppel-like factor 4 is a mediator of proinflammatory signaling in macrophages. J Biol Chem 2005; 280:38247-58. PubMed
  • Feinberg MW, Jain MK. Role of transforming growth factor-beta1/Smads in regulating vascular inflammation and atherogenesis. Panminerva Med 2006; 47:169-86. PubMed
  • Feinberg MW, Lin Z, Fisch S, Jain MK. An emerging role for Krpel-like factors in vascular biology. Trends Cardiovasc Med 2004; 14:241-6. PubMed
  • Feinberg MW, Shimizu K, Lebedeva M, Haspel R, Takayama K, Chen Z, Frederick JP, Wang XF, Simon DI, Libby P, Mitchell RN, Jain MK. Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation. Circ Res 2004; 94:601-8. PubMed