Photo of Mary Ann Stevenson,  MD, Ph

Mary Ann Stevenson, MD, Ph

Beth Israel Deaconess Medical Center

Beth Israel Deaconess Medical Center
Phone: (617) 667-4984
Fax: (617) 667-4934


mstevens@bidmc.harvard.edu

Mary Ann Stevenson, MD, Ph

Beth Israel Deaconess Medical Center

EDUCATIONAL TITLES

  • Associate Professor, Radiation Oncology, Harvard Medical School
  • Chairman, Radiation Oncology, Beth Israel Deaconess Medical Center

DF/HCC PROGRAM AFFILIATION

Research Abstract

Identification and characterization of radiation-induced signal transduction pathways

Publications

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  • Michaelson EM, Chen YH, Silver B, Tishler RB, Marcus KJ, Stevenson MA, Ng AK. Thyroid malignancies in survivors of Hodgkin lymphoma. Int J Radiat Oncol Biol Phys 2014; 88:636-41. PubMed
  • Calderwood SK, Gong J, Stevenson MA, Murshid A. Cellular and molecular chaperone fusion vaccines: targeting resistant cancer cell populations. Int J Hyperthermia 2013; 29:376-9. PubMed
  • Calderwood SK, Stevenson MA, Murshid A. Heat shock proteins, autoimmunity, and cancer treatment. Autoimmune Dis 2012; 2012:486069. PubMed
  • Galper SL, Yu JB, Mauch PM, Strasser JF, Silver B, Lacasce A, Marcus KJ, Stevenson MA, Chen MH, Ng AK. Clinically significant cardiac disease in patients with Hodgkin lymphoma treated with mediastinal irradiation. Blood 2010. PubMed
  • Chen RC, Chin MS, Ng AK, Feng Y, Neuberg D, Silver B, Pinkus GS, Stevenson MA, Mauch PM. Early-stage, lymphocyte-predominant Hodgkin's lymphoma: patient outcomes from a large, single-institution series with long follow-up. J Clin Oncol 2009; 28:136-41. PubMed
  • Rodrigues NA,Killion L,Hickey G,Silver B,Martin C,Stevenson MA,Mauch PM,Ng AK. A Prospective Study of Salivary Gland Function in Lymphoma Patients Receiving Head and Neck Irradiation. Int J Radiat Oncol Biol Phys 2009; 75:1079-83. PubMed
  • Recht A, Ancukiewicz M, Alm El-Din MA, Lu XQ, Martin C, Berman SM, Hirsch AE, Kachnic LA, Katz A, MacDonald S, Nedea EA, Stevenson MA, Powell SN, Taghian AG. Lung dose-volume parameters and the risk of pneumonitis for patients treated with accelerated partial-breast irradiation using three-dimensional conformal radiotherapy. J Clin Oncol 2009; 27:3887-93. PubMed
  • Balboni TA, Chen MH, Harris JR, Recht A, Stevenson MA, D'Amico AV. Academic career selection and retention in radiation oncology: the joint center for radiation therapy experience. Int J Radiat Oncol Biol Phys 2007; 68:183-6. PubMed
  • Ng AK, Li S, Neuberg D, Fisher DC, McMillan C, Silver B, Marcus KC, Stevenson MA, Mauch PM. Long-term results of a prospective trial of mantle irradiation alone for early-stage Hodgkin's disease. Ann Oncol 2006; 17:1693-7. PubMed
  • Das P, Ng AK, Stevenson MA, Mauch PM. Clinical course of thoracic cancers in Hodgkin's disease survivors. Ann Oncol 2005; 16:793-7. PubMed
  • Ng AK, Bernardo MV, Silver B, Van Den Abbeele A, Stevenson MA, Fisher DC, Mauch PM. Mid- and post-ABVD gallium scanning predicts for recurrence in early-stage Hodgkin's disease. Int J Radiat Oncol Biol Phys 2005; 61:175-84. PubMed
  • Ng AK, Li S, Neuberg D, Silver B, Stevenson MA, Fisher DC, Mauch PM. Comparison of MOPP versus ABVD as salvage therapy in patients who relapse after radiation therapy alone for Hodgkin's disease. Ann Oncol 2004; 15:270-5. PubMed
  • Stevenson MA, Zhao MJ, Asea A, Coleman CN, Calderwood SK. Salicylic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of cyclic AMP response element binding protein- and NF-kappa B-responsive genes. J Immunol 1999; 163:5608-16. PubMed
  • Swingler S, Mann A, Jacqu. HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nat Med 1999; 5:997-103. PubMed
  • Chen C, Xie Y, Stevenson MA, Auron PE, Calderwood SK. Heat shock factor 1 represses Ras-induced transcriptional activation of the c-fos gene. J Biol Chem 1997; 272:26803-6. PubMed
  • Chu B, Soncin F, Price BD, Stevenson MA, Calderwood SK. Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional activation by heat shock factor-1. J Biol Chem 1996; 271:30847-57. PubMed
  • Stevenson MA, Pollock SS, Coleman CN, Calderwood SK. X-irradiation, phorbol esters, and H2O2 stimulate mitogen-activated protein kinase activity in NIH-3T3 cells through the formation of reactive oxygen intermediates. Cancer Res 1994; 54:12-5. PubMed
  • Calderwood SK, Stevenson MA, Price BD. Activation of phospholipase C by heat shock requires GTP analogs and is resistant to pertussis toxin. J Cell Physiol 1993; 156:153-9. PubMed
  • Stevenson MA, Calderwood SK. Members of the 70-kilodalton heat shock protein family contain a highly conserved calmodulin-binding domain. Mol Cell Biol 1990; 10:1234-8. PubMed
  • Calderwood SK, Bornstein B, Farnum EK, Stevenson MA. Heat shock stimulates the release of arachidonic acid and the synthesis of prostaglandins and leukotriene B4 in mammalian cells. J Cell Physiol 1989; 141:325-33. PubMed
  • Calderwood SK, Stevenson MA, Hahn GM. Effects of heat on cell calcium and inositol lipid metabolism. Radiat Res 1988; 113:414-25. PubMed
  • Stevenson MA, Calderwood SK, Hahn GM. Effect of hyperthermia (45 degrees C) on calcium flux in Chinese hamster ovary HA-1 fibroblasts and its potential role in cytotoxicity and heat resistance. Cancer Res 1987; 47:3712-7. PubMed
  • Calderwood SK, Stevenson MA, Hahn GM. Heat stress stimulates inositol trisphosphate release and phosphorylation of phosphoinositides in CHO and Balb C 3T3 cells. J Cell Physiol 1987; 130:369-76. PubMed
  • Calderwood SK, Stevenson MA, Modlinsky M, Hahn GM. Binding of polycation DEAE-dextran to Chinese hamster ovary cells induces reversible Ca2+ influx and inhibits capping of concanavalin A acceptor proteins. Biochim Biophys Acta 1986; 889:316-25. PubMed
  • Stevenson MA, Calderwood SK, Hahn GM. Rapid increases in inositol trisphosphate and intracellular Ca++ after heat shock. Biochem Biophys Res Commun 1986; 137:826-33. PubMed
  • Stevenson MA, Minton KW, Hahn GM. Survival and concanavalin-A-induced capping in CHO fibroblasts after exposure to hyperthermia, ethanol, and X irradiation. Radiat Res 1981; 86:467-78. PubMed
  • Minton KW, Stevenson MA, Kendig J, Hahn GM. Pressure inhibits thermal killing of Chinese hamster ovary fibroblasts. Nature 1980; 285:482-3. PubMed
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