Mary B. Landrum, PhD

Harvard Medical School

Harvard Medical School
Phone: (617) 432-2460
Fax: (617) 432-2563


landrum@hcp.med.harvard.edu

Mary B. Landrum, PhD

Harvard Medical School

EDUCATIONAL TITLES

  • Professor, Health Care Policy, Harvard Medical School

DF/HCC PROGRAM AFFILIATION

Research Abstract

Dr. Landrum's primary research focus is on the development and application of statistical methodology for health services research. This research has several related themes including the development of medical guidelines, the profiling of health care providers, and methods for causal inference with observational data. Dr. Landrum has developed and applied methodology for profiling health care providers - in particular methods for assessing providers on more than one dimension of care. Dr. Landrum is also involved in a number of studies examining patterns and quality of care and their subsequent impac on patient outcomes. Some areas here include: differences in the use of procedures, medications, and preventive services between heart attack patients with HMO and fee-for-service insurance; quality of HIV care and changes in care subsequent to quality training; effect of managed care on the quality of care provided to patients with hypertension, diabetes and cancer; physician and patient characteristics related to the use of adjuvant tamoxifen therapy in elderly breast cancer patients; the impact of primary and specialty care on the diagnosis, treatment, and surveillance of elderly patients with breast cancer; and the development of quality indicators for advanced cancer care.

Publications

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  • Kehl KL, Landrum MB, Kahn KL, Gray SW, Chen AB, Keating NL. Tumor board participation among physicians caring for patients with lung or colorectal cancer. J Oncol Pract 2015; 11:e267-78. PubMed
  • Hobbs GS, Landrum MB, Arora NK, Ganz PA, van Ryn M, Weeks JC, Mack JW, Keating NL. The role of families in decisions regarding cancer treatments. Cancer 2015; 121:1079-87. PubMed
  • Kehl KL, Landrum MB, Arora NK, Ganz PA, van Ryn M, Mack JW, Keating NL. Association of Actual and Preferred Decision Roles With Patient-Reported Quality of Care: Shared Decision Making in Cancer Care. JAMA Oncol 2015; 1:50-8. PubMed
  • Romanus D, Cardarella S, Cutler D, Landrum MB, Lindeman NI, Gazelle GS. Cost-effectiveness of multiplexed predictive biomarker screening in non-small-cell lung cancer. J Thorac Oncol 2015; 10:586-94. PubMed
  • Samuel CA, Zaslavsky AM, Landrum MB, Lorenz K, Keating NL. Developing and Evaluating Composite Measures of Cancer Care Quality. Med Care 2014; 53:54-64. PubMed
  • Samuel CA, Landrum MB, McNeil BJ, Bozeman SR, Williams CD, Keating NL. Racial disparities in cancer care in the Veterans Affairs health care system and the role of site of care. Am J Public Health 2014; 104 Suppl 4:S562-71. PubMed
  • Lamont EB, Zaslavsky AM, Subramanian SV, Meilleur AE, He Y, Landrum MB. Elderly breast and colorectal cancer patients' clinical course: patient and contextual influences. Med Care 2014; 52:809-17. PubMed
  • Keating NL, Landrum MB, Lamont EB, Bozeman SR, Shulman LN, McNeil BJ. Tumor boards and the quality of cancer care. Journal of the National Cancer Institute 2013; 105:113-21. PubMed
  • Brooks JM, Chrischilles EA, Landrum MB, Wright KB, Fang G, Winer EP, Keating NL. Survival implications associated with variation in mastectomy rates for early-staged breast cancer. Int J Surg Oncol 2012; 2012:127854. PubMed
  • He Y, Zaslavsky A, Landrum M, Harrington D, Catalano P. Multiple imputation in a large-scale complex survey: a practical guide. 2010; 19:653-70. PubMed
  • Keating NL, Beth Landrum M, Arora NK, Malin JL, Ganz PA, van Ryn M, Weeks JC. Cancer patients' roles in treatment decisions: do characteristics of the decision influence roles? J Clin Oncol 2010; 28:4364-70. PubMed
  • Keating NL, Landrum MB, Lamont EB, Earle CC, Bozeman SR, McNeil BJ. End-of-life care for older cancer patients in the Veterans Health Administration versus the private sector. Cancer 2010; 116:3732-9. PubMed
  • Rogers SO, Gray SW, Landrum MB, Klabunde CN, Kahn KL, Fletcher RH, Clauser S, Tisnado D, Doucette W, Keating NL. Variations in Surgeon Treatment Recommendations for Lobectomy in Early-Stage Non-Small-Cell Lung Cancer by Patient Age and Comorbidity. Ann Surg Oncol 2010; 17:1581-8. PubMed
  • Keating NL, Landrum MB, Brooks JM, Chrischilles EA, Winer EP, Wright K, Volya R. Outcomes following local therapy for early-stage breast cancer in non-trial populations. Breast Cancer Res Treat 2010. PubMed
  • Oh WK, Landrum MB, Lamont EB, McNeil BJ, Keating NL. Does oral antiandrogen use before leuteinizing hormone-releasing hormone therapy in patients with metastatic prostate cancer prevent clinical consequences of a testosterone flare? Urology 2010; 75:642-7. PubMed
  • Keating NL, Landrum MB, Rogers SO, Baum SK, Virnig BA, Huskamp HA, Earle CC, Kahn KL. Physician factors associated with discussions about end-of-life care. Cancer 2010; 116:998-1006. PubMed
  • Lamont EB, Landrum MB, Keating NL, Archer L, Lan L, Strauss GM, Lilenbaum R, Niell HB, Maurer LH, Kosty MP, Miller AA, Clamon GH, Elias AD, McClay EF, Vokes EE, McNeil BJ. Differences in clinical trial patient attributes and outcomes according to enrollment setting. J Clin Oncol 2010; 28:215-21. PubMed
  • Norredam M, Meara E, Landrum MB, Huskamp HA, Keating NL. Financial status, employment, and insurance among older cancer survivors. J Gen Intern Med 2009; 24 Suppl 2:S438-45. PubMed
  • Lee IH,Hayman JA,Landrum MB,Tepper J,Tao ML,Goodman KA,Keating NL. Treatment Recommendations for Locally Advanced, Non-Small-Cell Lung Cancer: The Influence of Physician and Patient Factors. Int J Radiat Oncol Biol Phys 2009; 74:1376-84. PubMed
  • Earle CC,Landrum MB,Souza JM,Neville BA,Weeks JC,Ayanian JZ. Aggressiveness of cancer care near the end of life: is it a quality-of-care issue? J Clin Oncol 2008; 26:3860-6. PubMed
  • Keating NL,Landrum MB,Klabunde CN,Fletcher RH,Rogers SO,Doucette WR,Tisnado D,Clauser S,Kahn KL. Adjuvant chemotherapy for stage III colon cancer: do physicians agree about the importance of patient age and comorbidity? J Clin Oncol 2008; 26:2532-7. PubMed
  • Keating NL, Landrum MB, Guadagnoli E, Winer EP, Ayanian JZ. Care in the months before death and hospice enrollment among older women with advanced breast cancer. J Gen Intern Med 2007; 23:11-8. PubMed
  • Landrum MB, Meara ER, Chandra A, Guadagnoli E, Keating NL. Is spending more always wasteful? The appropriateness of care and outcomes among colorectal cancer patients. Health Aff (Millwood) 2008; 27:159-68. PubMed
  • Huskamp HA, Deverka PA, Landrum MB, Epstein RS, McGuigan KA. The effect of three-tier formulary adoption on medication continuation and spending among elderly retirees. Health Serv Res 2007; 42:1926-42. PubMed
  • Hasnain-Wynia R, Baker DW, Nerenz D, Feinglass J, Beal AC, Landrum MB, Behal R, Weissman JS. Disparities in health care are driven by where minority patients seek care: examination of the hospital quality alliance measures. Arch Intern Med 2007; 167:1233-9. PubMed
  • Busch AB, Huskamp HA, Landrum MB. Quality of care in a medicaid population with bipolar I disorder. Psychiatr Serv 2007; 58:848-54. PubMed
  • Keating NL, Landrum MB, Landon BE, Ayanian JZ, Borbas C, Guadagnoli E. The influence of cost containment strategies and physicians' financial arrangements on patients' trust and satisfaction. J Ambul Care Manage 2007; 30:92-104. PubMed
  • Keating NL, Landrum MB, Guadagnoli E, Winer EP, Ayanian JZ. Surveillance testing among survivors of early-stage breast cancer. J Clin Oncol 2007; 25:1074-81. PubMed
  • Hasnain-Wynia R, Baker DW, Nerenz D, Feinglass J, Beal AC, Landrum MB, Behal R, Weissman JS. Disparities in Health Care Driven by Where Minority Patient Seek Care: Examination of the Hospital Quality Alliance Measures Arch Intern Med 2006.
  • Huskamp HA, Deverka PA, Landrum MB, Epstein RS, McGuigan KA. The effect of three-tier formulary adoption on medication continuation and spending among elderly retirees Health Affairs 2006.
  • Rosenthal MB, Landrum MB, Meara E, Huskamp HA, Conti RM, Keating NL. Using performance data to identify preferred hospitals. Health Serv Res 2006.
  • Keating NL, Landrum MB, Meara E, Ganz PA, Guadagnoli E. Managed care market share and primary treatment for cancer. Health Serv Res 2006; 41:9-22. PubMed
  • Keating NL, Landrum MB, Guadagnoli E, Winer EP, Ayanian JZ. Factors related to underuse of surveillance mammography among breast cancer survivors. J Clin Oncol 2005; 24:85-94. PubMed
  • Keating NL, N. Physical and mental health status of older long-term cancer survivors. J Am Geriatr Soc 2006; 53:2145-52. PubMed
  • Earle CC, Neville BA, Beth Landrum M, Souza JM, Weeks JC, Block SD, Grunfeld E, Ayanian JZ. Evaluating claims-based indicators of the intensity of end-of-life cancer care. Int J Qual Health Care 2005; 17:505-9. PubMed
  • Keating NL, Landrum MB, Meara E, Ganz PA, Guadagnoli E. Do increases in the market share of managed care influence quality of cancer care in the fee-for-service sector? J Natl Cancer Inst 2005; 97:257-64. PubMed
  • Earle CC, Neville BA, Landrum MB, Ayanian JZ, Block SD, Weeks JC. Trends in the aggressiveness of cancer care near the end of life. J Clin Oncol 2004; 22:315-21. PubMed
  • Keating NL, Landrum MB, Ayanian JZ, Winer EP, Guadagnoli E. Consultation with a medical oncologist before surgery and type of surgery among elderly women with early-stage breast cancer. J Clin Oncol 2003; 21:4532-9. PubMed
  • Cutler DM, Gruber J, Hartman RS, Landrum MB, Newhouse JP, Rosenthal MB. The economic impacts of the tobacco settlement. J Policy Anal Manage 2002; 21:1-19. PubMed
  • Garg PP, Landrum MB, Normand SL, Ayanian JZ, Hauptman PJ, Ryan TJ, McNeil BJ, Guadagnoli E. Understanding individual and small area variation in the underuse of coronary angiography following acute myocardial infarction. Med Care 2002; 40:614-26. PubMed
  • Silliman RA, Guadagnoli E, Rakowski W, Landrum MB, Lash TL, Wolf R, Fink A, Ganz PA, Gurwitz J, Borbas C, Mor V. Adjuvant tamoxifen prescription in women 65 years and older with primary breast cancer. J Clin Oncol 2002; 20:2680-8. PubMed
  • Ayanian JZ, Landrum MB, McNeil BJ. Use of cholesterol-lowering therapy by elderly adults after myocardial infarction. Arch Intern Med 2002; 162:1013-9. PubMed
  • Bronskill SE, Normand SL, Landrum MB, Rosenheck RA. Longitudinal profiles of health care providers. Stat Med 2002; 21:1067-88. PubMed
  • Keating NL, Guadagnoli E, Landrum MB, Borbas C, Weeks JC. Treatment decision making in early-stage breast cancer: should surgeons match patients' desired level of involvement? J Clin Oncol 2002; 20:1473-9. PubMed
  • Ayanian JZ, Landon BE, Landrum MB, Grana JR, McNeil BJ. Use of cholesterol-lowering therapy and related beliefs among middle-aged adults after myocardial infarction. J Gen Intern Med 2002; 17:95-102. PubMed
  • Gurwitz JH, Guadagnoli E, Landrum MB, Silliman RA, Wolf R, Weeks JC. The treating physician as active gatekeeper in the recruitment of research subjects. Med Care 2001; 39:1339-44. PubMed
  • Landrum MB, Becker MP. A multiple imputation strategy for incomplete longitudinal data. Stat Med 2001; 20:2741-60. PubMed
  • Keating NL, Weeks JC, Landrum MB, Borbas C, Guadagnoli E. Discussion of treatment options for early-stage breast cancer: effect of provider specialty on type of surgery and satisfaction. Med Care 2001; 39:681-91. PubMed
  • Seddon ME, Ayanian JZ, Landrum MB, Cleary PD, Peterson EA, Gahart MT, McNeil BJ. Quality of ambulatory care after myocardial infarction among Medicare patients by type of insurance and region. Am J Med 2001; 111:24-32. PubMed
  • Guadagnoli E, Landrum MB, Normand SL, Ayanian JZ, Garg P, Hauptman PJ, Ryan TJ, McNeil BJ. Impact of underuse, overuse, and discretionary use on geographic variation in the use of coronary angiography after acute myocardial infarction. Med Care 2001; 39:446-58. PubMed
  • Normand ST, Landrum MB, Guadagnoli E, Ayanian JZ, Ryan TJ, Cleary PD, McNeil BJ. Validating recommendations for coronary angiography following acute myocardial infarction in the elderly: a matched analysis using propensity scores. J Clin Epidemiol 2001; 54:387-98. PubMed
  • Guadagnoli E, Landrum MB, Peterson EA, Gahart MT, Ryan TJ, McNeil BJ. Appropriateness of coronary angiography after myocardial infarction among Medicare beneficiaries. Managed care versus fee for service. N Engl J Med 2000; 343:1460-6. PubMed
  • Keating NL, Landrum MB, Klabunde CN, Fletcher RH, Rogers SO, Doucette WR, Tisnado D, Clauser S, Kahn KL.. Adjuvant chemotherapy for stage III colon cancer: do physicians agree about the importance of patient age and comorbidity? J Clin Oncol 2008; 26:2532-7.
  • Landrum MB, McNeil BJ, Silva L, Normand SL. Understanding variability in physician ratings of the appropriateness of coronary angiography after acute myocardial infarction. J Clin Epidemiol 1999; 52:309-19. PubMed
  • Landrum MB, Normand SL. Applying Bayesian ideas to the development of medical guidelines. Stat Med 1999; 18:117-37. PubMed
  • Ayanian JZ, Landrum MB, Normand SL, Guadagnoli E, McNeil BJ. Rating the appropriateness of coronary angiography--do practicing physicians agree with an expert panel and with each other? N Engl J Med 1998; 338:1896-904. PubMed
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