Photo of Michael A. Gimbrone,   M.D.

Michael A. Gimbrone, M.D.

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 732-5901
Fax: (617) 732-5933


mgimbrone@rics.bwh.harvard.edu

Michael A. Gimbrone, M.D.

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Elsie T. Friedman Professor, Pathology, Harvard Medical School
  • Chair, Pathology, Brigham And Women's Hospital

Publications

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  • Dai G, Vaughn S, Zhang Y, Wang ET, Garcia-Cardena G, Gimbrone MA Jr. Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2. Circ Res 2007; 101:723-33. PubMed
  • Gerszten RE, Garcia-Zepeda EA, Lim YC, Yoshida M, Ding HA, Gimbrone MA, Luster AD, Luscinskas FW, Rosenzweig A. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature 1999; 398:718-23. PubMed
  • Topper JN, DiChiara MR, Brown JD, Williams AJ, Falb D, Collins T, Gimbrone MA. CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor beta transcriptional responses in endothelial cells. Proc Natl Acad Sci U S A 1998; 95:9506-11. PubMed
  • Milstone DS, Fukumura D, Padgett RC, O'Donnell PE, Davis VM, Benavidez OJ, Monsky WL, Melder RJ, Jain RK, Gimbrone MA. Mice lacking E-selectin show normal numbers of rolling leukocytes but reduced leukocyte stable arrest on cytokine-activated microvascular endothelium. Microcirculation 1998; 5:153-71. PubMed
  • Yoshida M, Westlin WF, Wang N, Ingber DE, Rosenzweig A, Resnick N, Gimbrone MA. Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton. J Cell Biol 1996; 133:445-55. PubMed
  • Collins T, Williams A, Johnston GI, Kim J, Eddy R, Shows T, Gimbrone MA, Bevilacqua MP. Structure and chromosomal location of the gene for endothelial-leukocyte adhesion molecule 1. J Biol Chem 1991; 266:2466-73. PubMed
  • Bevilacqua MP, Pober JS, Mendrick DL, Cotran RS, Gimbrone MA. Identification of an inducible endothelial-leukocyte adhesion molecule. Proc Natl Acad Sci U S A 1987; 84:9238-42. PubMed
  • Bussolari SR, Dewey CF, Gimbrone MA. Apparatus for subjecting living cells to fluid shear stress. Rev Sci Instrum 1982; 53:1851-4. PubMed
  • Gunther S, Alexander RW, Atkinson WJ, Gimbrone MA. Functional angiotensin II receptors in cultured vascular smooth muscle cells. J Cell Biol 1982; 92:289-98. PubMed
  • Hial V, Gimbrone MA, Peyton MP, Wilcox GM, Pisano JJ. Angiotensin metabolism by cultured human vascular endothelial and smooth muscle cells. Microvasc Res 1979; 17:314-29. PubMed
  • Gimbrone MA, Aster RH, Cotran RS, Corkery J, Jandl JH, Folkman J. Preservation of vascular integrity in organs perfused in vitro with a platelet-rich medium. Nature 1969; 221:33-6. PubMed