Photo of Michael M. Givertz,  MD

Michael M. Givertz, MD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 732-7367
Fax: (617) 264-5265


mgivertz@partners.org

Michael M. Givertz, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Associate Professor, Medicine, Harvard Medical School
  • Co-Director, Cardiomyopathy and Heart Failure Program, Cardiovascular Medicine, Brigham And Women's Hospital

Research Abstract

Within the broad field of heart failure, I have a well-defined interest in the pathophysiology of dilated cardiomyopathy. My clinical research has focused on the functional significance of nitric oxide and oxidative stress in human myocardial failure, and the role of endothelin in pulmonary hypertension. Towards these ends, I have carried out invasive physiologic studies in the cardiac catheterization laboratory using selective intracoronary and intrapulmonary infusions. In addition, I have focused my research efforts on the non-invasive assessment of hemodynamics in heart failure, and have worked with biotechnology and pharmaceutical companies in the development of novel pharmacological and device therapies for heart failure.

Publications

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  • Givertz MM. Adenosine A1 receptor antagonists at a fork in the road. Circ Heart Fail 2009; 2:519-22. PubMed
  • Fonarow GC, Peacock WF, Horwich TB, Phillips CO, Givertz MM, Lopatin M, Wynne J. Usefulness of B-type natriuretic peptide and cardiac troponin levels to predict in-hospital mortality from ADHERE. Am J Cardiol 2008; 101:231-7. PubMed
  • Givertz MM, Massie BM, Fields TK, Pearson LL, Dittrich HC. The effects of KW-3902, an adenosine A1-receptor antagonist,on diuresis and renal function in patients with acute decompensated heart failure and renal impairment or diuretic resistance. J Am Coll Cardiol 2007; 50:1551-60. PubMed