Photo of Michael T. Jaklitsch,  MD

Michael T. Jaklitsch, MD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 732-6988
Fax: (617) 730-2898

Michael T. Jaklitsch, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Professor, Surgery, Harvard Medical School
  • Thoracic Surgeon, Thoracic Surgery, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

The elderly patient is particularly susceptible to suffer morbidity after major thoracic surgical procedures. Previous work from Brigham & Women's Hospital has shown that this subgroup has a thirteen-fold higher incidence of postoperative dementia after non-cardiac thoracic surgery. The full recovery time from major thoracic surgical procedures is poorly understood in this subgroup. This is an extremely pertinent issue. Current data are unavailable to advise the eighty-five-year-old patient with a presumed early stage lung cancer as to which treatment option may be expected to maximize the future quality of life. New instruments of measurement are required to address these issues. I am currently developing clinical measurements of the elderly patient's functional status, motivation for surgery, understanding of surgery, and quality of life. I plan to test these measurements in our outpatient elderly population over the next year.

Publications

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  • Gill RR, Zheng Y, Barlow JS, Jayender J, Girard EE, Hartigan PM, Chirieac LR, Belle-King CJ, Murray K, Sears C, Wee JO, Jaklitsch MT, Colson YL, Bueno R. Image-guided video assisted thoracoscopic surgery (iVATS) - phase I-II clinical trial. J Surg Oncol 2015; 112:18-25. PubMed
  • Jaklitsch MT. "How am I doing? Just ask me!" The usefulness of patient self-reported quality of life in thoracic surgery. J Thorac Cardiovasc Surg 2015; 149:663-4. PubMed
  • Mazzone P, Powell CA, Arenberg D, Bach P, Detterbeck F, Gould MK, Jaklitsch MT, Jett J, Naidich D, Vachani A, Wiener RS, Silvestri G. Components necessary for high-quality lung cancer screening: American College of Chest Physicians and American Thoracic Society Policy Statement. Chest 2015; 147:295-303. PubMed
  • Pallis AG, Gridelli C, Wedding U, Faivre-Finn C, Veronesi G, Jaklitsch M, Luciani A, O'Brien M. Management of elderly patients with NSCLC; updated expert's opinion paper: EORTC Elderly Task Force, Lung Cancer Group and International Society for Geriatric Oncology. Ann Oncol 2014; 25:1270-83. PubMed
  • Mohiuddin K, Haneuse S, Sofer T, Gill R, Jaklitsch MT, Colson YL, Wee J, Bueno R, Mentzer SJ, Sugarbaker DJ, Swanson SJ. Relationship between margin distance and local recurrence among patients undergoing wedge resection for small (竕、2 cm) non-small cell lung cancer. J Thorac Cardiovasc Surg 2014; 147:1169-75; discussion 1175-7. PubMed
  • Jaklitsch MT. Meeting the challenges of centrally located non-small-cell lung cancer. Oncology (Huntingt) 2014; 28:221, 227-8. PubMed
  • Gill RR, Jaklitsch MT, Jacobson FL. Controversies in lung cancer screening. J Am Coll Radiol 2013; 10:931-6. PubMed
  • Jacobson FL, Jaklitsch MT. Low-dose CT screening for lung cancer: the time is now. J Surg Oncol 2013; 108:265-9. PubMed
  • Gilmore DM, Khullar OV, Jaklitsch MT, Chirieac LR, Frangioni JV, Colson YL. Identification of metastatic nodal disease in a phase 1 dose-escalation trial of intraoperative sentinel lymph node mapping in non-small cell lung cancer using near-infrared imaging. J Thorac Cardiovasc Surg 2013; 146:562-70; discussion 569-70. PubMed
  • Jaklitsch MT, Gu L, Demmy T, Harpole DH, D'Amico TA, McKenna RJ, Krasna MJ, Kohman LJ, Swanson SJ, DeCamp MM, Wang X, Barry S, Sugarbaker DJ, . Prospective phase II trial of preresection thoracoscopic mediastinal restaging after neoadjuvant therapy for IIIA (N2) non-small cell lung cancer: results of CALGB Protocol 39803. J Thorac Cardiovasc Surg 2013; 146:9-16. PubMed
  • Billmeier SE, Ayanian JZ, He Y, Jaklitsch MT, Rogers SO. Predictors of nursing home admission, severe functional impairment, or death one year after surgery for non-small cell lung cancer. Ann Surg 2013; 257:555-63. PubMed
  • Oxman DA, Issa NC, Marty FM, Patel A, Panizales CZ, Johnson NN, Licona JH, McKenna SS, Frendl G, Mentzer SJ, Jaklitsch MT, Bueno R, Colson Y, Swanson SJ, Sugarbaker DJ, Baden LR. Postoperative Antibacterial Prophylaxis for the Prevention of Infectious Complications Associated With Tube Thoracostomy in Patients Undergoing Elective General Thoracic Surgery: A Double-blind, Placebo-Controlled, Randomized Trial. JAMA Surg 2013. PubMed
  • Jaklitsch MT, Jacobson FL. Reply to the editor. J Thorac Cardiovasc Surg 2012; 145:308. PubMed
  • Lee MS, Mamon HJ, Hong TS, Choi NC, Fidias PM, Kwak EL, Meyerhardt JA, Ryan DP, Bueno R, Donahue DM, Jaklitsch MT, Lanuti M, Rattner DW, Fuchs CS, Enzinger PC. Preoperative cetuximab, irinotecan, Cisplatin, and radiation therapy for patients with locally advanced esophageal cancer. Oncologist 2013; 18:281-7. PubMed
  • Jacobson FL, Jaklitsch MT. Lung cancer screening trials: the United States and beyond. J Thorac Cardiovasc Surg 2012; 144:S3-6. PubMed
  • Jacobson FL, Austin JH, Field JK, Jett JR, Keshavjee S, MacMahon H, Mulshine JL, Munden RF, Salgia R, Strauss GM, Sugarbaker DJ, Swanson SJ, Travis WD, Jaklitsch MT. Development of The American Association for Thoracic Surgery guidelines for low-dose computed tomography scans to screen for lung cancer in North America: recommendations of The American Association for Thoracic Surgery Task Force for Lung Cancer Screenin J Thorac Cardiovasc Surg 2012; 144:25-32. PubMed
  • Jaklitsch MT, Jacobson FL, Austin JH, Field JK, Jett JR, Keshavjee S, MacMahon H, Mulshine JL, Munden RF, Salgia R, Strauss GM, Swanson SJ, Travis WD, Sugarbaker DJ. The American Association for Thoracic Surgery guidelines for lung cancer screening using low-dose computed tomography scans for lung cancer survivors and other high-risk groups. J Thorac Cardiovasc Surg 2012; 144:33-8. PubMed
  • Sugarbaker DJ, Wolf AS, Chirieac LR, Godleski JJ, Tilleman TR, Jaklitsch MT, Bueno R, Richards WG. Clinical and pathological features of three-year survivors of malignant pleural mesothelioma following extrapleural pneumonectomy. 2011. PubMed
  • Richards WG, Godleski JJ, Yeap BY, Corson JM, Chirieac LR, Zellos L, Mujoomdar A, Jaklitsch MT, Bueno R, Sugarbaker DJ. Proposed adjustments to pathologic staging of epithelial malignant pleural mesothelioma based on analysis of 354 cases. Cancer 2010; 116:1510-7. PubMed
  • Goguen LA, Norris CM, Jaklitsch MT, Sullivan CA, Posner MR, Haddad RI, Tishler RB, Burke E, Annino DJ. Combined antegrade and retrograde esophageal dilation for head and neck cancer-related complete esophageal stenosis. Laryngoscope 2010; 120:261-6. PubMed
  • Cooley ME,Sarna L,Kotlerman J,Lukanich JM,Jaklitsch M,Green SB,Bueno R. Smoking cessation is challenging even for patients recovering from lung cancer surgery with curative intent. Lung Cancer 2009; 66:218-25. PubMed
  • Tilleman TR, Richards WG, Zellos L, Johnson BE, Jaklitsch MT, Mueller J, Yeap BY, Mujoomdar AA, Ducko CT, Bueno R, Sugarbaker DJ. Extrapleural pneumonectomy followed by intracavitary intraoperative hyperthermic cisplatin with pharmacologic cytoprotection for treatment of malignant pleural mesothelioma: a phase II prospective study. J Thorac Cardiovasc Surg 2009; 138:405-11. PubMed
  • Khalpey Z, Camp P, Jaklitsch MT. Left circumflex to bronchial artery fistula. Ann Thorac Surg 2009; 88:303. PubMed
  • Paul S,Escareno CE,Clancy K,Jaklitsch MT,Bueno R,Lautz DB. Gastrointestinal complications after lung transplantation. J Heart Lung Transplant 2009; 28:475-9. PubMed
  • Zellos L,Richards WG,Capalbo L,Jaklitsch MT,Chirieac LR,Johnson BE,Bueno R,Sugarbaker DJ. A phase I study of extrapleural pneumonectomy and intracavitary intraoperative hyperthermic cisplatin with amifostine cytoprotection for malignant pleural mesothelioma. J Thorac Cardiovasc Surg 2009; 137:453-8. PubMed
  • Neragi-Miandoab S, Linden PA, Ducko CT, Bueno R, Richards WG, Sugarbaker DJ, Jaklitsch MT. VATS pericardiotomy for patients with known malignancy and pericardial effusion: survival and prognosis of positive cytology and metastatic involvement of the pericardium: a case control study. Int J Surg 2008; 6:110-4. PubMed
  • Hodi FS, Butler M, Oble DA, Seiden MV, Haluska FG, Kruse A, Macrae S, Nelson M, Canning C, Lowy I, Korman A, Lautz D, Russell S, Jaklitsch MT, Ramaiya N, Chen TC, Neuberg D, Allison JP, Mihm MC, Dranoff G. Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients. Proc Natl Acad Sci U S A 2008; 105:3005-10. PubMed
  • Linden PA, Wee JO, Jaklitsch MT, Colson YL. Extending indications for radiofrequency ablation of lung tumors through an intraoperative approach. Ann Thorac Surg 2008; 85:420-3. PubMed
  • Chang MY, Mentzer SJ, Colson YL, Linden PA, Jaklitsch MT, Lipsitz SR, Sugarbaker DJ. Factors predicting poor survival after resection of stage IA non-small cell lung cancer. J Thorac Cardiovasc Surg 2007; 134:850-6. PubMed
  • Silletti JP, Gordon GJ, Bueno R, Jaklitsch M, Loughlin KR. Prostate biopsy: past, present, and future. Urology 2007; 69:413-6. PubMed
  • Linden PA, Bueno R, Mentzer SJ, Zellos L, Lebenthal A, Colson YL, Sugarbaker DJ, Jaklitsch MT. Modified T-tube repair of delayed esophageal perforation results in a low mortality rate similar to that seen with acute perforations. Ann Thorac Surg 2007; 83:1129-33. PubMed
  • Linden PA, Yeap BY, Chang MY, Henderson WG, Jaklitsch MT, Khuri S, Sugarbaker DJ, Bueno R. Morbidity of lung resection after prior lobectomy: results from the Veterans Affairs National Surgical Quality Improvement Program. Ann Thorac Surg 2007; 83:425-31; discussion 432. PubMed
  • Jaklitsch MT, Herndon JE, DeCamp MM, Richards WG, Kumar P, Krasna MJ, Green MR, Sugarbaker DJ. Nodal downstaging predicts survival following induction chemotherapy for stage IIIA (N2) non-small cell lung cancer in CALGB protocol #8935. J Surg Oncol 2006; 94:599-606. PubMed
  • Richards WG, Zellos L, Bueno R, Jaklitsch MT, J. Phase I to II study of pleurectomy/decortication and intraoperative intracavitary hyperthermic cisplatin lavage for mesothelioma. J Clin Oncol 2006; 24:1561-7. PubMed
  • Mukhopadhyay NK, Weisberg E, Gilchrist D, Bueno R, Sugarbaker DJ, Jaklitsch MT. Effectiveness of trichostatin A as a potential candidate for anticancer therapy in non-small-cell lung cancer. Ann Thorac Surg 2006; 81:1034-42. PubMed
  • Linden PA, Gilbert RJ, Yeap BY, Boyle K, Deykin A, Jaklitsch MT, Sugarbaker DJ, Bueno R. Laparoscopic fundoplication in patients with end-stage lung disease awaiting transplantation. J Thorac Cardiovasc Surg 2006; 131:438-46. PubMed
  • Mery CM, Pappas AN, Burt BM, Bueno R, Linden PA, Sugarbaker DJ, Jaklitsch MT. Diameter of non-small cell lung cancer correlates with long-term survival: implications for T stage. Chest 2005; 128:3255-60. PubMed
  • Mery CM, Pappas AN, Bueno R, Colson YL, Linden P, Sugarbaker DJ, Jaklitsch MT. Similar long-term survival of elderly patients with non-small cell lung cancer treated with lobectomy or wedge resection within the surveillance, epidemiology, and end results database. Chest 2005; 128:237-45. PubMed
  • Mukhopadhyay NK, Gordon GJ, Maulik G, Doerre G, Liu BC, Bueno R, Sugarbaker DJ, Jaklitsch MT. Histone deacetylation is directly involved in desilencing the expression of the catalytic subunit of telomerase in normal lung fibroblast. J Cell Mol Med 2005; 9:662-9. PubMed
  • Ingenito EP, Tsai LW, Mentzer SJ, Jaklitsch MT, Reilly JJ, Lutchen K, Mazan M, Hoffman A. Respiratory impedance following bronchoscopic or surgical lung volume reduction for emphysema. Respiration 2005; 72:406-17. PubMed
  • Linden PA, Bueno R, Colson YL, Jaklitsch MT, Lukanich J, Mentzer S, Sugarbaker DJ. Lung resection in patients with preoperative FEV1 < 35% predicted. Chest 2005; 127:1984-90. PubMed
  • Mukhopadhyay NK, Gordon GJ, Chen CJ, Bueno R, Sugarbaker DJ, Jaklitsch MT. Activation of focal adhesion kinase in human lung cancer cells involves multiple and potentially parallel signaling events. J Cell Mol Med 2005; 9:387-97. PubMed
  • Mamon HJ, Yeap BY, J. High risk of brain metastases in surgically staged IIIA non-small-cell lung cancer patients treated with surgery, chemotherapy, and radiation. J Clin Oncol 2005; 23:1530-7. PubMed
  • VanSonnenberg E, Shankar S, Morrison PR, Nair RT, Silverman SG, Jaklitsch MT, Liu F, Cheung L, Tuncali K, Skarin AT, Sugarbaker DJ. Radiofrequency ablation of thoracic lesions: part 2, initial clinical experience--technical and multidisciplinary considerations in 30 patients. AJR Am J Roentgenol 2005; 184:381-90. PubMed
  • Sugarbaker DJ, Jaklitsch MT, Bueno R, Richards W, Lukanich J, Mentzer SJ, Colson Y, Linden P, Chang M, Capalbo L, Oldread E, Neragi-Miandoab S, Swanson SJ, Zellos LS. Prevention, early detection, and management of complications after 328 consecutive extrapleural pneumonectomies. J Thorac Cardiovasc Surg 2004; 128:138-46. PubMed
  • Mery CM, Pappas AN, Bueno R, Mentzer SJ, Lukanich JM, Sugarbaker DJ, Jaklitsch MT. Relationship between a history of antecedent cancer and the probability of malignancy for a solitary pulmonary nodule. Chest 2004; 125:2175-81. PubMed
  • Audisio RA, Bozzetti F, Gennari R, Jaklitsch MT, Koperna T, Longo WE, Wiggers T, Zbar AP. The surgical management of elderly cancer patients; recommendations of the SIOG surgical task force. Eur J Cancer 2004; 40:926-38. PubMed
  • Jaklitsch MT, Pappas-Estocin A, Bueno R. Thoracoscopic surgery in elderly lung cancer patients. Crit Rev Oncol Hematol 2004; 49:165-71. PubMed
  • Moore KA, Mery CM, Jaklitsch MT, P Estocin A, Bueno R, Swanson SJ, Sugarbaker DJ, Lukanich JM. Menopausal effects on presentation, treatment, and survival of women with non-small cell lung cancer. Ann Thorac Surg 2003; 76:1789-95. PubMed
  • Soiffer R, Hodi FS, Haluska F, Jung K, Gillessen S, Singer S, Tanabe K, Duda R, Mentzer S, Jaklitsch M, Bueno R, Clift S, Hardy S, Neuberg D, Mulligan R, Webb I, Mihm M, Dranoff G. Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. J Clin Oncol 2003; 21:3343-50. PubMed
  • Gordon GJ, Richards WG, Sugarbaker DJ, Jaklitsch MT, Bueno R. A prognostic test for adenocarcinoma of the lung from gene expression profiling data. Cancer Epidemiol Biomarkers Prev 2003; 12:905-10. PubMed
  • Jaklitsch MT, Mery CM, Audisio RA. The use of surgery to treat lung cancer in elderly patients. Lancet Oncol 2003; 4:463-71. PubMed
  • Davison BD, Ring DH, Bueno R, Jaklitsch MT. Endovascular stent-graft repair of a pulmonary artery-bronchial fistula. J Vasc Interv Radiol 2003; 14:929-32. PubMed
  • Irie HY, Jaklitsch MT, Shaffer K, Weinstein M, Salgia R. Unusual problems in breast cancer and a rare lung cancer case. Case 4. Primary lymphoepithelioma-like carcinoma of the lung. J Clin Oncol 2003; 21:2220-2. PubMed
  • Gordon GJ, Jensen RV, Hsiao LL, Gullans SR, Blumenstock JE, Richards WG, Jaklitsch MT, Sugarbaker DJ, Bueno R. Using gene expression ratios to predict outcome among patients with mesothelioma. J Natl Cancer Inst 2003; 95:598-605. PubMed
  • Hodi FS, Mihm MC, Soiffer RJ, Haluska FG, Butler M, Seiden MV, Davis T, Henry-Spires R, MacRae S, Willman A, Padera R, Jaklitsch MT, Shankar S, Chen TC, Korman A, Allison JP, Dranoff G. Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc Natl Acad Sci U S A 2003; 100:4712-7. PubMed
  • Kukreja J, Jaklitsch MT. Section IV: selective use of neoadjuvant therapy. Semin Thorac Cardiovasc Surg 2003; 15:187-96. PubMed
  • Salgia R, Lynch T, Skarin A, Lucca J, Lynch C, Jung K, Hodi FS, Jaklitsch M, Mentzer S, Swanson S, Lukanich J, Bueno R, Wain J, Mathisen D, Wright C, Fidias P, Donahue D, Clift S, Hardy S, Neuberg D, Mulligan R, Webb I, Sugarbaker D, Mihm M, Dranoff G. Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma. J Clin Oncol 2003; 21:624-30. PubMed
  • Gordon GJ, Appasani K, Parcells JP, Mukhopadhyay NK, Jaklitsch MT, Richards WG, Sugarbaker DJ, Bueno R. Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma. Carcinogenesis 2002; 23:1017-24. PubMed
  • Gordon GJ, Chen CJ, Jaklitsch MT, Richards WG, Sugarbaker DJ, Bueno R. Detection and quantification of SV40 large T-antigen DNA in mesothelioma tissues and cell lines. Oncol Rep 2002; 9:631-4. PubMed
  • Harte BH, Jaklitsch MT, McKenna SS, Body SC. Use of a modified single-lumen endobronchial tube in severe tracheobronchial compression. Anesthesiology 2002; 96:510-1. PubMed
  • Murthy S, Looney J, Jaklitsch MT. Gastropericardial fistula after laparoscopic surgery for reflux disease. N Engl J Med 2002; 346:328-32. PubMed
  • Swanson SJ, Batirel HF, Bueno R, Jaklitsch MT, Lukanich JM, Allred E, Mentzer SJ, Sugarbaker DJ. Transthoracic esophagectomy with radical mediastinal and abdominal lymph node dissection and cervical esophagogastrostomy for esophageal carcinoma. Ann Thorac Surg 2002; 72:1918-24; discussion 1924-. PubMed
  • Bueno R, Swanson SJ, Jaklitsch MT, Lukanich JM, Mentzer SJ, Sugarbaker DJ. Combined antegrade and retrograde dilation: a new endoscopic technique in the management of complex esophageal obstruction. Gastrointest Endosc 2001; 54:368-72. PubMed
  • Jaklitsch MT, Linden BC, Braunlin EA, Bolman RM, Foker JE. Open-lung biopsy guides therapy in children. Ann Thorac Surg 2001; 71:1779-85. PubMed
  • Jaklitsch MT, Mery CM, Lukanich JM, Richards WG, Bueno R, Swanson SJ, Mentzer SJ, Davis BD, Allred EN, Sugarbaker DJ. Sequential thoracic metastasectomy prolongs survival by re-establishing local control within the chest. J Thorac Cardiovasc Surg 2001; 121:657-67. PubMed
  • Bueno R, Richards WG, Swanson SJ, Jaklitsch MT, Lukanich JM, Mentzer SJ, Sugarbaker DJ. Nodal stage after induction therapy for stage IIIA lung cancer determines patient survival. Ann Thorac Surg 2001; 70:1826-31. PubMed
  • Swanson SJ, Mentzer SJ, Reilly JJ, Bueno R, Lukanich JM, Jaklitsch MT, Kobzik L, Ingenito EP, Fuhlbrigge A, Donovan C, McKee C, Boyle K, Fagan GP, Sugarbaker DJ. Surveillance transbronchial lung biopsies: implication for survival after lung transplantation. J Thorac Cardiovasc Surg 1999; 119:27-37. PubMed
  • Jaklitsch MT, Bueno R, Swanson SJ, Mentzer SJ, Lukanich JM, Sugarbaker DJ. New surgical options for elderly lung cancer patients. Chest 2000; 116:480S-485S. PubMed
  • Swanson SJ, Jaklitsch MT, Mentzer SJ, Bueno R, Lukanich JM, Sugarbaker DJ. Management of the solitary pulmonary nodule: role of thoracoscopy in diagnosis and therapy. Chest 2000; 116:523S-524S. PubMed
  • DeCamp MM, Swanson SJ, Jaklitsch MT. Esophagectomy after induction chemoradiation. Chest 2000; 116:466S-469S. PubMed
  • Jaklitsch MT, Byrne JG, Mery C. Thymoma encasing last patent vein graft to the heart. J Thorac Cardiovasc Surg 1999; 118:561-3. PubMed
  • Liu G, Rosenfield Darling ML, Chan J, Jaklitsch MT, Skarin AT. Gynecomastia in a patient with lung cancer. J Clin Oncol 1999; 17:1956. PubMed
  • Sugarbaker DJ, Flores RM, Jaklitsch MT, Richards WG, Strauss GM, Corson JM, DeCamp MM, Swanson SJ, Bueno R, Lukanich JM, Baldini EH, Mentzer SJ. Resection margins, extrapleural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: results in 183 patients. J Thorac Cardiovasc Surg 1998; 117:54-63; discussion 63-5. PubMed
  • Flores RM, Jaklitsch MT, DeCamp MM, Sugarbaker DJ. Video-assisted thoracic surgery pericardial resection for effusive disease. Chest Surg Clin N Am 1999; 8:835-51. PubMed
  • Jaklitsch MT, Rego A. Endorsement for sparing the clavicle in the transcervical approach to the thoracic inlet. J Thorac Cardiovasc Surg 1997; 113:959-61. PubMed
  • Jaklitsch MT, DeCamp MM, Liptay MJ, Harpole DH, Swanson SJ, Mentzer SJ, Sugarbaker DJ. Video-assisted thoracic surgery in the elderly. A review of 307 cases. Chest 1996; 110:751-8. PubMed
  • Krasna MJ, Reed CE, Jaklitsch MT, Cushing D, Sugarbaker DJ. Thoracoscopic staging of esophageal cancer: a prospective, multiinstitutional trial. Cancer and Leukemia Group B Thoracic Surgeons. Ann Thorac Surg 1995; 60:1337-40. PubMed
  • DeCamp MM, Jaklitsch MT, Mentzer SJ, Harpole DH, Sugarbaker DJ. The safety and versatility of video-thoracoscopy: a prospective analysis of 895 consecutive cases. J Am Coll Surg 1995; 181:113-20. PubMed
  • Sugarbaker DJ, Jaklitsch MT, Liptay MJ. Thoracoscopic staging and surgical therapy for esophageal cancer. Chest 1995; 107:218S-223S. PubMed
  • Sugarbaker DJ, Jaklitsch MT, Liptay MJ. Mesothelioma and radical multimodality therapy: who benefits? Chest 1995; 107:345S-350S. PubMed
  • Jaklitsch MT, Strauss GM, Healey EA, DeCamp MM, Liptay MJ, Sugarbaker DJ. An historical perspective of multi-modality treatment for resectable non-small cell lung cancer. Lung Cancer 1995; 12 Suppl 2:S17-32. PubMed
  • Banai S, Jaklitsch MT, Shou M, Lazarous DF, Scheinowitz M, Biro S, Epstein SE, Unger EF. Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs. Circulation 1994; 89:2183-9. PubMed
  • Unger EF, Banai S, Shou M, Lazarous DF, Jaklitsch MT, Scheinowitz M, Correa R, Klingbeil C, Epstein SE. Basic fibroblast growth factor enhances myocardial collateral flow in a canine model. Am J Physiol 1994; 266:H1588-95. PubMed
  • Unger EF, Banai S, Shou M, Jaklitsch M, Hodge E, Correa R, Jaye M, Epstein SE. A model to assess interventions to improve collateral blood flow: continuous administration of agents into the left coronary artery in dogs. Cardiovasc Res 1993; 27:785-91. PubMed
  • Jaklitsch MT, Biro S, Casscells W, Dichek DA. Transduced endothelial cells expressing high levels of tissue plasminogen activator have an unaltered phenotype in vitro. J Cell Physiol 1993; 154:207-16. PubMed
  • Flugelman MY, Jaklitsch MT, Newman KD, Casscells W, Bratthauer GL, Dichek DA. Low level in vivo gene transfer into the arterial wall through a perforated balloon catheter. Circulation 1992; 85:1110-7. PubMed
  • Banai S, Shou M, Correa R, Jaklitsch MT, Douek PC, Bonner RF, Epstein SE, Unger EF. Rabbit ear model of injury-induced arterial smooth muscle cell proliferation. Kinetics, reproducibility, and implications. Circ Res 1991; 69:748-56. PubMed
  • Banai S, Jaklitsch MT, Casscells W, Shou M, Shrivastav S, Correa R, Epstein SE, Unger EF. Effects of acidic fibroblast growth factor on normal and ischemic myocardium. Circ Res 1991; 69:76-85. PubMed
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