Photo of Motaz Qadan,  MD, PhD

Motaz Qadan, MD, PhD

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 643-5153


mqadan@mgh.harvard.edu

Motaz Qadan, MD, PhD

Massachusetts General Hospital

EDUCATIONAL TITLES

  • Assistant Professor, Surgery, Harvard Medical School
  • Assistant in Surgery, Surgery, Massachusetts General Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

My research focuses on the tumor microenvironment in the treatment of pancreas cancer. Pancreas cancer is a highly resilient tumor and by influencing the environment and character of the tumor, early data suggests that the disease may be rendered more susceptible to treatments including chemotherapy, radiation, and immunotherapy. I am currently involved in setting up clinical trials related to novel agents in this field.

In addition, I am interested in clinical outcomes research that focuses on methods to collect, analyze, and improve outcomes related to cancer surgery at the National level. I conducts my outcomes research at the Codman Center for Clinical Effectiveness in Surgery. Some of my current interests include optimization of patients who are due to undergo oncologic surgery by improving their nutritional, physical, and psychological well-being prior to operation, as well as a specific focus on surgical intervention in the palliative setting.

Publications

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  • Qadan M, D'Angelica MI. Extending the Limits of Resection for Colorectal Liver Metastases: Positive Resection Margin and Outcome After Resection of Colorectal Cancer Liver Metastases. J Gastrointest Surg 2016; 21:196-198. PubMed
  • Qadan M, Kingham TP. Technical Aspects of Gallbladder Cancer Surgery. Surg Clin North Am 2016; 96:229-45. PubMed
  • Qadan M, Garden OJ, Corvera CU, Visser BC. Management of Postoperative Hepatic Failure. J Am Coll Surg 2016; 222:195-208. PubMed
  • Qadan M, D'Angelica MI. Complex Surgical Strategies to Improve Resectability in Borderline-Resectable Disease. 2017; 11:369-377. PubMed
  • McAuliffe JC, Qadan M, D'Angelica MI. Hepatic resection, hepatic arterial infusion pump therapy, and genetic biomarkers in the management of hepatic metastases from colorectal cancer. J Gastrointest Oncol 2015; 6:699-708. PubMed
  • Tran TB, Qadan M, Dua MM, Norton JA, Poultsides GA, Visser BC. Prognostic relevance of lymph node ratio and total lymph node count for small bowel adenocarcinoma. Surgery 2015; 158:486-93. PubMed
  • Qadan M, Dua M, Worhunsky D, Triadafilopoulos G, Visser B. More with less: pancreas-preserving total duodenectomy. Dig Dis Sci 2015; 60:1565-8. PubMed
  • Dua MM, Qadan M, Lutchman GA, Park WG, Triadafilopoulos G, Visser BC. Non-MalIg(G4)nant Biliary Obstruction: When the Pill Is Mightier than the Knife. Dig Dis Sci 2015; 60:1178-82. PubMed
  • Worhunsky DJ, Qadan M, Dua MM, Park WG, Poultsides GA, Norton JA, Visser BC. Laparoscopic transgastric necrosectomy for the management of pancreatic necrosis. J Am Coll Surg 2014; 219:735-43. PubMed
  • Qadan M, Ma Y, Visser BC, Kunz PL, Fisher GA, Norton JA, Poultsides GA. Reassessment of the current American Joint Committee on Cancer staging system for pancreatic neuroendocrine tumors. J Am Coll Surg 2014; 218:188-95. PubMed
  • Qadan M, Curet MJ, Wren SM. The evolving application of single-port robotic surgery in general surgery. J Hepatobiliary Pancreat Sci 2013; 21:26-33. PubMed
  • Qadan M, Akca O. Reassessing the role of supplemental oxygen in the prevention of surgical site infection. Ann Surg 2012; 256:902-3. PubMed
  • Billeter AT, Qadan M, Druen D, Gardner SA, The T, Polk HC. Does clinically relevant temperature change miRNA and cytokine expression in whole blood? J. Interferon Cytokine Res. 2012; 32:485-94. PubMed
  • Qadan M, Clarke S, Morrow E, Triadafilopoulos G, Visser B. Sump syndrome as a complication of choledochoduodenostomy. Dig Dis Sci 2012; 57:2011-5. PubMed
  • Qadan M, Visser B, Kim J, Pai R, Triadafilopoulos G. Abdominal mass, anemia, diabetes mellitus, and necrolytic migratory erythema. Dig Dis Sci 2012; 57:1465-8. PubMed
  • Billeter AT, Polk HC, Hohmann SF, Qadan M, Fry DE, Jorden JR, McCafferty MH, Galandiuk S. Mortality after elective colon resection: the search for outcomes that define quality in surgical practice. J Am Coll Surg 2012; 214:436-43; discussion 443-4. PubMed
  • Lamb AD, Qadan M, Roberts S, Timlin H, Vowler SL, Campbell FM, Grigor K, Bartlett JM, McNeill SA. CD4+ and CD8+ T-lymphocyte scores cannot reliably predict progression in patients with benign prostatic hyperplasia. BJU Int 2011; 108:E43-50. PubMed
  • Qadan M, Kastenberg Z, Carvalho B, Sultan P. Crossing the pond: applying to train in the USA. Br J Hosp Med (Lond) 2011; 72:M50-2. PubMed
  • Qadan M, Polk HC, Hohmann SF, Fry DE. A reassessment of needs and practice patterns in pharmacologic prophylaxis of venous thromboembolism following elective major surgery. Ann Surg 2011; 253:215-20. PubMed
  • Kirkpatrick AW, Papia G, McCloskey SA, Polk HC, Akca O, Qadan M, . CAGS and ACS evidence based reviews in surgery. 36. Effect of high perioperative oxygen fraction on surgical site infection. Can J Surg 2011; 54:67-9. PubMed
  • Dickinson A, Qadan M, Weller C, Gardner S, Polk HC. In vitro study of variables relevant to perioperative care of the surgical patient: glucose, osmolarity, and rewarming. J Am Coll Surg 2011; 212:180-6. PubMed
  • Lenz AM, Qadan M, Gardner SA, Cheadle WG. Impact of microbial tolerance in persistent secondary Klebsiella pneumoniae peritonitis. Cytokine 2010; 53:84-93. PubMed
  • Brown RE, Qadan M, Martin RC, Polk HC. The evolving importance of readmission data to the practicing surgeon. J Am Coll Surg 2010; 211:558-60. PubMed
  • Qadan M, Battista C, Gardner SA, Anderson G, Akca O, Polk HC. Oxygen and surgical site infection: a study of underlying immunologic mechanisms. Anesthesiology 2010; 113:369-77. PubMed
  • Watkins JM, Qadan M, Battista C, Polk HC. A closer look at surgical quality measures across different surgical specialties. Am J Surg 2010; 200:90-6. PubMed
  • Cronen P, Qadan M, Hicks NZ, Polk HC. Standards of surgery beyond metropolitan centers: a fresh look at perioperative quality measures in small-town America. Am J Surg 2010; 200:97-104. PubMed
  • Kanaan Z, Qadan M, Eichenberger MR, Galandiuk S. The actin-cytoskeleton pathway and its potential role in inflammatory bowel disease-associated human colorectal cancer. Genet Test Mol Biomarkers 2010; 14:347-53. PubMed
  • Qadan M, Weller EB, Gardner SA, Maldonado C, Fry DE, Polk HC. Glucose and surgical sepsis: a study of underlying immunologic mechanisms. J Am Coll Surg 2010; 210:966-74. PubMed
  • Dickinson A, Qadan M, Polk HC. Optimizing surgical care: a contemporary assessment of temperature, oxygen, and glucose. Am Surg 2010; 76:571-7. PubMed
  • Qadan M, Cheadle WG. Controversies in host defense against surgical site infection. Expert Rev Anti Infect Ther 2009; 7:1043-7. PubMed
  • Qadan M, Gardner SA, Vitale DS, Lominadze D, Joshua IG, Polk HC. Hypothermia and surgery: immunologic mechanisms for current practice. Ann Surg 2009; 250:134-40. PubMed
  • Polk HC, Vitale DS, Qadan M. The very busy urban surgeon: another face of the evermore obvious shortage of general surgeons. J Am Coll Surg 2009; 209:144-7. PubMed
  • Qadan M, Cheadle WG. Common microbial pathogens in surgical practice. Surg Clin North Am 2009; 89:295-310, vii. PubMed
  • Qadan M, Ak├ža O, Mahid SS, Hornung CA, Polk HC. Perioperative supplemental oxygen therapy and surgical site infection: a meta-analysis of randomized controlled trials. Arch Surg 2009; 144:359-66; discussion 366-7. PubMed
  • Qadan M, Tyson M, McCafferty MH, Hohmann SF, Polk HC. Venous thromboembolism in elective operations: balancing the choices. Surgery 2008; 144:654-60, discussion 660-1. PubMed
  • Lamb AD, Qadan M, Gray AJ. Detection of occult pneumothoraces in the significantly injured adult with blunt trauma. Eur J Emerg Med 2007; 14:65-7. PubMed
  • Chia S, Qadan M, Newton R, Ludlam CA, Fox KA, Newby DE. Intra-arterial tumor necrosis factor-alpha impairs endothelium-dependent vasodilatation and stimulates local tissue plasminogen activator release in humans. Arterioscler Thromb Vasc Biol 2003; 23:695-701. PubMed
  • Ahdoot M, Qadan M, Santa-Maria M, Kennedy WA, Ilano A. Indirect inguinal hernia with uterine tissue in a male: A case of persistent Mullerian duct syndrome and literature review. Can Urol Assoc J 2013; 7:E121-4. PubMed
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