Photo of Nancy A. Rigotti,  MD

Nancy A. Rigotti, MD

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 724-3548
Fax: (617) 724-6774

Nancy A. Rigotti, MD

Massachusetts General Hospital


  • Professor, Medicine, Harvard Medical School
  • Professor, Population Medicine, Harvard Medical School
  • Director, Tobacco Research and Treatment Unit, Massachusetts General Hospital


Research Abstract

Nancy Rigotti, MD, is an internationally known expert in tobacco use, tobacco cessation, and tobacco control public policy. Trained as a general internist, she is Associate Chief of the Division of General Internal Medicine at Massachusetts General Hospital, a Professor of Medicine at Harvard Medical School, and Past President of both the Society of General Internal Medicine and the Society for Research in Nicotine and Tobacco. Dr. Rigotti founded and directs the Tobacco Research and Treatment Center at Massachusetts General Hospital. This program combines a clinical service (MGH Tobacco Treatment Smoking Service) with a multidisciplinary research group whose mission is to develop innovative and effective smoking cessation treatment and tobacco control policy approaches. Her research includes formal evaluations of the effects of tobacco control public policy and clinical and outcomes research studies testing behavioral and pharmacologic smoking cessation treatments. Her current research focuses on developing and testing systems that embed tobacco dependence treatment into the evolving U.S. health care delivery system, with a special interest in using hospitalization as an opportunity to promote tobacco cessation. With colleagues from the Tobacco Research and Treatment Center and DFHCC, Dr. Rigotti is also testing smoking cessation interventions targeting patients with cancer, peripheral vascular disease, parents of children attending pediatric practices, and patients in primary care practices.



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  • Kruse GR, Rigotti NA, Raw M, McNeill A, Murray R, PinĂ©-Abata H, Bitton A, McEwen A. Tobacco Dependence Treatment Training Programs: An International Survey. Nicotine Tob Res 2015. PubMed
  • Park ER, Gareen IF, Japuntich S, Lennes I, Hyland K, DeMello S, Sicks JD, Rigotti NA. Primary Care Provider-Delivered Smoking Cessation Interventions and Smoking Cessation Among Participants in the National Lung Screening Trial. JAMA Intern Med 2015. PubMed
  • Japuntich SJ, Luberto CM, Streck JM, Rigotti NA, Temel J, Lanuti M, Dresler C, Zallen JP, Davies D, Park ER. Integrating tobacco treatment into thoracic oncology settings: Lessons learned. J Health Psychol 2015. PubMed
  • Regan S, Reid ZZ, Kelley JH, Reyen M, Korotkin M, Japuntich SJ, Viana JC, Levy DE, Rigotti NA. Smoking Status Confirmation by Proxy: Validation in a Smoking Cessation Trial. Nicotine Tob Res 2015. PubMed
  • Rigotti NA. Improving the success of treating tobacco smokers. JAMA Intern Med 2015; 175:272-3. PubMed
  • Haas JS, Linder JA, Park ER, Gonzalez I, Rigotti NA, Klinger EV, Kontos EZ, Zaslavsky AM, Brawarsky P, Marinacci LX, St Hubert S, Fleegler EW, Williams DR. Proactive tobacco cessation outreach to smokers of low socioeconomic status: a randomized clinical trial. JAMA Intern Med 2015; 175:218-26. PubMed
  • Rigotti NA, Wu M. Advising patients about electronic cigarettes. Eur Heart J 2015; 36:135-6. PubMed
  • Reid ZZ, Regan S, Kelley JH, Streck JM, Ylioja T, Tindle HA, Chang Y, Levy DE, Park ER, Singer DE, Carpenter KM, Reyen M, Rigotti NA. Comparative effectiveness of post-discharge strategies for hospitalized smokers: study protocol for the Helping HAND 2 randomized controlled trial. BMC Public Health 2015; 15:109. PubMed
  • Japuntich SJ, Eilers MA, Shenhav S, Park ER, Winickoff JP, Benowitz NL, Rigotti NA. Secondhand tobacco smoke exposure among hospitalized nonsmokers with coronary heart disease. JAMA Intern Med 2015; 175:133-6. PubMed
  • Winickoff JP, Nabi-Burza E, Chang Y, Regan S, Drehmer J, Finch S, Wasserman R, Ossip D, Hipple B, Woo H, Klein J, Rigotti NA. Sustainability of a Parental Tobacco Control Intervention in Pediatric Practice. Pediatrics 2014. PubMed
  • Kruse GR, Rigotti NA. Routine screening of hospital patients for secondhand tobacco smoke exposure: A feasibility study. Prev Med 2014; 69C:141-145. PubMed
  • Rigotti NA, Park ER, Streck J, Chang Y, Reyen M, McKool K, Winickoff JP. An intervention to address secondhand tobacco smoke exposure among nonsmokers hospitalized with coronary heart disease. Am J Cardiol 2014; 114:1040-5. PubMed
  • Rigotti NA, Regan S, Levy DE, Japuntich S, Chang Y, Park ER, Viana JC, Kelley JH, Reyen M, Singer DE. Sustained care intervention and postdischarge smoking cessation among hospitalized adults: a randomized clinical trial. JAMA 2014; 312:719-28. PubMed
  • Drehmer JE, Ossip DJ, Nabi-Burza E, Rigotti NA, Hipple B, Woo H, Chang Y, Winickoff JP. Thirdhand smoke beliefs of parents. Pediatrics 2014; 133:e850-6. PubMed
  • Kruse GR, Bangsberg DR, Hahn JA, Haberer JE, Hunt PW, Muzoora C, Bennett JP, Martin JN, Rigotti NA. Tobacco Use Among Adults Initiating Treatment for HIV Infection in Rural Uganda. AIDS Behav 2014. PubMed
  • Park ER, Streck JM, Gareen IF, Ostroff JS, Hyland KA, Rigotti NA, Pajolek H, Nichter M. A qualitative study of lung cancer risk perceptions and smoking beliefs among national lung screening trial participants. Nicotine Tob Res 2014; 16:166-73. PubMed
  • Rigotti NA, Regan S, Levy DE, Japuntich SJ, Chang Y, Park ER, Viana JC, Kelley JHK, Reyen M, Singer DE.. Sustained care intervention and post-discharge smoking cessation among hospitalized adults: a randomized clinical trial JAMA 2014; 312:719-728.
  • Bernstein SL, Yu S, Post LA, Dziura J, Rigotti NA. Undertreatment of tobacco use relative to other chronic conditions. Am J Public Health 2013; 103:e59-65. PubMed
  • Winickoff JP, Nabi-Burza E, Chang Y, Finch S, Regan S, Wasserman R, Ossip D, Woo H, Klein J, Dempsey J, Drehmer J, Hipple B, Weiley V, Murphy S, Rigotti NA. Implementation of a parental tobacco control intervention in pediatric practice. Pediatrics 2013; 132:109-17. PubMed
  • Park ER, Gareen IF, Jain A, Ostroff JS, Duan F, Sicks JD, Rakowski W, Diefenbach M, Rigotti NA. Examining whether lung screening changes risk perceptions: National Lung Screening Trial participants at 1-year follow-up. Cancer 2013; 119:1306-13. PubMed
  • Carpenter MJ, Jardin BF, Burris JL, Mathew AR, Schnoll RA, Rigotti NA, Cummings KM. Clinical strategies to enhance the efficacy of nicotine replacement therapy for smoking cessation: a review of the literature. Drugs 2013; 73:407-26. PubMed
  • Levy DE, Rigotti NA, Winickoff JP. Tobacco smoke exposure in a sample of Boston public housing residents. Am J Prev Med 2012; 44:63-6. PubMed
  • Friebely J, Rigotti NA, Chang Y, Hall N, Weiley V, Dempsey J, Hipple B, Nabi-Burza E, Murphy S, Woo H, Winickoff JP. Parent smoker role conflict and planning to quit smoking: a cross-sectional study. BMC Public Health 2013; 13:164. PubMed
  • Drehmer JE, Ossip DJ, Rigotti NA, Nabi-Burza E, Woo H, Wasserman RC, Chang Y, Winickoff JP. Pediatrician interventions and thirdhand smoke beliefs of parents. Am J Prev Med 2012; 43:533-6. PubMed
  • Rigotti NA. Strategies to help a smoker who is struggling to quit. JAMA 2012; 308:1573-80. PubMed
  • Rigotti NA, Wakefield M. Real People, Real Stories: A New Mass Media Campaign That Could Help Smokers Quit. Ann Intern Med 2012. PubMed
  • Japuntich SJ, Regan S, Viana J, Tymoszcuk J, Reyen M, Levy DE, Singer DE, Park ER, Chang Y, Rigotti NA. Comparative effectiveness of post-discharge interventions for hospitalized smokers: study protocol for a randomized controlled trial. Trials 2012; 13:124. PubMed
  • Land TG, Rigotti NA, Levy DE, Schilling T, Warner D, Li W. The effect of systematic clinical interventions with cigarette smokers on quit status and the rates of smoking-related primary care office visits. PLoS ONE 2012; 7:e41649. PubMed
  • Regan S, Reyen M, Lockhart AC, Richards AE, Rigotti NA. An interactive voice response system to continue a hospital-based smoking cessation intervention after discharge. Nicotine Tob Res 2011; 13:255-60. PubMed
  • Rigotti NA. Integrating comprehensive tobacco treatment into the evolving US health care system: it's time to act: comment on "A randomized trial of Internet and telephone treatment for smoking cessation". Arch Intern Med 2011; 171:53-5. PubMed
  • Bitton A, Raw M, Richards A, McNeill A, Rigotti NA. A comparison of four international surveys of tobacco dependence treatment provision: implications for monitoring the Framework Convention on Tobacco Control. Addiction 2010; 105:2184-91. PubMed
  • Baggett TP, Rigotti NA. Cigarette smoking and advice to quit in a national sample of homeless adults. Am J Prev Med 2010; 39:164-72. PubMed
  • Baggett TP, O'Connell JJ, Singer DE, Rigotti NA. The unmet health care needs of homeless adults: a national study. Am J Public Health 2010; 100:1326-33. PubMed
  • Winickoff JP, Healey EA, Regan S, Park ER, Cole C, Friebely J, Rigotti NA. Using the postpartum hospital stay to address mothers' and fathers' smoking: the NEWS study. Pediatrics 2010; 125:518-25. PubMed
  • Rigotti NA, Pipe AL, Benowitz NL, Arteaga C, Garza D, Tonstad S. Efficacy and safety of varenicline for smoking cessation in patients with cardiovascular disease: a randomized trial. Circulation 2010; 121:221-9. PubMed
  • Park ER, Chang Y, Quinn VP, Ross K, Rigotti NA. Perceived support to stay quit: what happens after delivery? Addict Behav 2009; 34:1000-4. PubMed
  • Thorndike AN, Rigotti NA. A tragic triad: coronary artery disease, nicotine addiction, and depression. Curr. Opin. Cardiol. 2009; 24:447-53. PubMed
  • Raw M, Regan S, Rigotti NA, McNeill A. A survey of tobacco dependence treatment guidelines in 31 countries. Addiction 2009; 104:1243-50. PubMed
  • Rigotti NA. Helping smokers with cardiac disease to abstain from tobacco after a stay in hospital. CMAJ 2009; 180:1283-4. PubMed
  • Rigotti NA. Addressing tobacco use in anesthesiology practice: a call to action. Anesthesiology 2009; 110:1207-8. PubMed
  • Park ER, Ostroff JS, Rakowski W, Gareen IF, Diefenbach MA, Feibelmann S, Rigotti NA. Risk perceptions among participants undergoing lung cancer screening: baseline results from the national lung screening trial. Ann Behav Med 2009; 37:268-79. PubMed
  • Linder JA,Rigotti NA,Schneider LI,Kelley JH,Brawarsky P,Haas JS. An electronic health record-based intervention to improve tobacco treatment in primary care: a cluster-randomized controlled trial. Arch Intern Med 2009; 169:781-7. PubMed
  • Rigotti NA. The future of tobacco treatment in the health care system. Ann Intern Med 2009; 150:496-7. PubMed
  • Levy DE,Biener L,Rigotti NA. The natural history of light smokers: A population-based cohort study. Nicotine Tob Res 2009; 11:156-63. PubMed
  • Quinn VP,Hollis JF,Smith KS,Rigotti NA,Solberg LI,Hu W,Stevens VJ. Effectiveness of the 5-As tobacco cessation treatments in nine HMOs. J Gen Intern Med 2008; 24:149-54. PubMed
  • Rigotti NA,Bitton A,Richards AE,Reyen M,Wassum K,Raw M. An international survey of training programs for treating tobacco dependence. Addiction 2009; 104:288-96. PubMed
  • Fagan P,Rigotti NA. Light and intermittent smoking: the road less traveled. Nicotine Tob Res 2009; 11:107-10. PubMed
  • Raw M,Regan S,Rigotti NA,McNeill A. A survey of tobacco dependence treatment services in 36 countries. Addiction 2009; 104:279-87. PubMed
  • Rigotti NA,Gonzales D,Dale LC,Lawrence D,Chang Y. A randomized controlled trial of adding the nicotine patch to rimonabant for smoking cessation: efficacy, safety and weight gain. Addiction 2009; 104:266-76. PubMed
  • Rigotti NA,Munafo MR,Stead LF. Smoking cessation interventions for hospitalized smokers: a systematic review. Arch Intern Med 2008; 168:1950-60. PubMed
  • Koplan KE,Regan S,Goldszer RC,Schneider LI,Rigotti NA. A computerized aid to support smoking cessation treatment for hospital patients. J Gen Intern Med 2008; 23:1214-7. PubMed
  • Winickoff JP,Park ER,Hipple BJ,Berkowitz A,Vieira C,Friebely J,Healey EA,Rigotti NA. Clinical effort against secondhand smoke exposure: development of framework and intervention. Pediatrics 2008; 122:e363-75. PubMed
  • Geller AC,Brooks DR,Powers CA,Brooks KR,Rigotti NA,Bognar B,McIntosh S,Zapka J. Tobacco cessation and prevention practices reported by second and fourth year students at US medical schools. J Gen Intern Med 2008; 23:1071-6. PubMed
  • Berg CJ,Park ER,Chang Y,Rigotti NA. Is concern about post-cessation weight gain a barrier to smoking cessation among pregnant women? Nicotine Tob Res 2008; 10:1159-63. PubMed
  • Rigotti NA, Park ER, Chang Y, Regan S. Smoking cessation medication use among pregnant and postpartum smokers. Obstet Gynecol 2008; 111:348-55. PubMed
  • Thorndike AN, Regan S, McKool K, Pasternak RC, Swartz S, Torres-Finnerty N, Rigotti NA. Depressive symptoms and smoking cessation after hospitalization for cardiovascular disease. Arch Intern Med 2008; 168:186-91. PubMed
  • Koplan KE, David SP, Rigotti NA. Smoking cessation. BMJ 2008; 336:217. PubMed
  • Levy DE, Thorndike AN, Biener L, Rigotti NA. Use of nicotine replacement therapy to reduce or delay smoking but not to quit: prevalence and association with subsequent cessation efforts. Tob Control 2007; 16:384-9. PubMed
  • Thorndike AN, Regan S, Rigotti NA. The treatment of smoking by US physicians during ambulatory visits: 1994 2003. Am J Public Health 2007; 97:1878-83. PubMed
  • Gelenberg AJ, de Leon J, Evins AE, Parks JJ, Rigotti NA. Smoking cessation in patients with psychiatric disorders. J Clin Psychiatry 2007; 68:1404-10. PubMed
  • Evins AE, Cather C, Culhane MA, Birnbaum A, Horowitz J, Hsieh E, Freudenreich O, Henderson DC, Schoenfeld DA, Rigotti NA, Goff DC. A 12-week double-blind, placebo-controlled study of bupropion sr added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia. J Clin Psychopharmacol 2007; 27:380-6. PubMed
  • Albers AB, Siegel M, Cheng DM, Biener L, Rigotti NA. Effect of smoking regulations in local restaurants on smokers' anti-smoking attitudes and quitting behaviours. Tobacco Control 2007; 16:101-6. PubMed
  • Thomson CC, Hamilton WL, Siegel MB, Biener L, Rigotti NA. Effect of local youth-access regulations on progression to established smoking among youths in Massachusetts. Tobacco Control 2007; 16:119-26. PubMed
  • Park ER, Quinn VP, Chang Y, Regan S, Loudin B, Cummins S, Perry K, Rigotti NA. Recruiting pregnant smokers into a clinical trial: using a network-model managed care organization versus community-based practices. Prev Med 2007; 44:223-9. PubMed
  • Rigotti NA, Munafo MR, Stead LF. Interventions for smoking cessation in hospitalised patients. Cochrane Database Syst Rev 2007. PubMed
  • Rigotti NA, Thorndike AN, Regan S, McKool K, Pasternak RC, Chang Y, Swartz S, Torres-Finnerty N, Emmons KM, Singer DE. Bupropion for smokers hospitalized with acute cardiovascular disease. Am J Med 2006; 119:1080-7. PubMed
  • Tindle HA, Rigotti NA, Davis RB, Barbeau EM, Kawachi I, Shiffman S. Cessation among smokers of "light" cigarettes: results from the 2000 national health interview survey. Am J Public Health 2006; 96:1498-504. PubMed
  • Jorenby DE, Hays JT, Rigotti NA, Azoulay S, Watsky EJ, Williams KE, Billing CB, Gong J, Reeves KR,. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA 2006; 296:56-63. PubMed
  • Rigotti NA, Park ER, Regan S, Chang Y, Perry K, Loudin B, Quinn V. Efficacy of telephone counseling for pregnant smokers: a randomized controlled trial. Obstet Gynecol 2006; 108:83-92. PubMed
  • Biener L, Reimer RL, Wakefield M, Szczypka G, Rigotti NA, Connolly G. Impact of smoking cessation aids and mass media among recent quitters. Am J Prev Med 2006; 30:217-24. PubMed
  • Conley Thomson C, Siegel M, Winickoff J, Biener L, Rigotti NA. Household smoking bans and adolescents' perceived prevalence of smoking and social acceptability of smoking. Prev Med 2005; 41:349-56. PubMed
  • Geller AC, Zapka J, Brooks KR, Dube C, Powers CA, Rigotti N, O'Donnell J, Ockene J,. Tobacco control competencies for US medical students. Am J Public Health 2005; 95:950-5. PubMed
  • Thorndike AN, Biener L, Rigotti NA. Effect on smoking cessation of switching nicotine replacement therapy to over-the-counter status. Am J Public Health 2002; 92:437-42. PubMed
  • Ossip DJ, Chang Y, Nabi-Burza E, Drehmer J, Finch S, Hipple B, Rigotti NA, Klein JD, Winickoff JP. Strict smoke-free home policies among smoking parents in pediatric settings. Acad Pediatr 2013; 13:517-23. PubMed