Photo of Pari V. Pandharipande,  MD, MPH

Pari V. Pandharipande, MD, MPH

Massachusetts General Hospital

Massachusetts General Hospital


ppandharipande@partners.org

Pari V. Pandharipande, MD, MPH

Massachusetts General Hospital

EDUCATIONAL TITLES

  • Assistant Professor, Radiology, Harvard Medical School
  • Director, Institute for Technology Assessment, Radiology, Massachusetts General Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

My career goal is to improve cancer outcomes by defining the best roles for imaging-based technologies in cancer care. I am an abdominal radiologist and health outcomes researcher at Massachusetts General Hospital, and Director of the MGH Institute for Technology Assessment. My research is centered in imaging, decision science, and risk analysis, with a focus in cancer modeling. I have studied the role of imaging technologies in multiple cancer settings, but have focused in renal and pancreatic cancers, and in radiation-induced cancer risks. Leveraging decision science methods, we have established - or refuted - the effectiveness and cost-effectiveness of imaging technologies in several clinical scenarios, and have brought new evidence and insights to their role in cancer care.

Publications

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  • Megibow AJ, Baker ME, Morgan DE, Kamel IR, Sahani DV, Newman E, Brugge WR, Berland LL, Pandharipande PV. Management of Incidental Pancreatic Cysts: A White Paper of the ACR Incidental Findings Committee. J Am Coll Radiol 2017; 14:911-923. PubMed
  • Herts BR, Silverman SG, Hindman NM, Uzzo RG, Hartman RP, Israel GM, Baumgarten DA, Berland LL, Pandharipande PV. Management of the Incidental Renal Mass on CT: A White Paper of the ACR Incidental Findings Committee. J Am Coll Radiol 2017. PubMed
  • Alkasab TK, Bizzo BC, Berland LL, Nair S, Pandharipande PV, Harvey HB. Creation of an Open Framework for Point-of-Care Computer-Assisted Reporting and Decision Support Tools for Radiologists. J Am Coll Radiol 2017. PubMed
  • Mayo-Smith WW, Song JH, Boland GL, Francis IR, Israel GM, Mazzaglia PJ, Berland LL, Pandharipande PV. Management of Incidental Adrenal Masses: A White Paper of the ACR Incidental Findings Committee. J Am Coll Radiol 2017. PubMed
  • Sheehan DF, Criss SD, Gazelle GS, Pandharipande PV, Kong CY. Evaluating lung cancer screening in China: Implications for eligibility criteria design from a microsimulation modeling approach. PLoS ONE 2017; 12:e0173119. PubMed
  • Pandharipande PV, Alabre CI, Coy DL, Zaheer A, Miller CM, Herring MS, Tramontano AC, Dowling EC, Eisenberg JD, Ashar BH, Halpern EF, Donelan K, Gazelle GS. Changes in Physician Decision Making after CT: A Prospective Multicenter Study in Primary Care Settings. Radiology 2016. PubMed
  • Besa C, Lewis S, Pandharipande PV, Chhatwal J, Kamath A, Cooper N, Knight-Greenfield A, Babb JS, Boffetta P, Padron N, Sirlin CB, Taouli B. Hepatocellular carcinoma detection: diagnostic performance of a simulated abbreviated MRI protocol combining diffusion-weighted and T1-weighted imaging at the delayed phase post gadoxetic acid. Abdom Radiol (NY) 2016. PubMed
  • Pandharipande PV, Herts BR, Gore RM, Mayo-Smith WW, Harvey HB, Megibow AJ, Berland LL. Rethinking Normal: Benefits and Risks of Not Reporting Harmless Incidental Findings. J Am Coll Radiol 2016; 13:764-7. PubMed
  • Kang SK, Huang WC, Skolnik EY, Gervais DA, Braithwaite RS, Pandharipande PV. Tumor Anatomy Scoring and Renal Function for Nephron-Sparing Treatment Selection in Patients With Small Renal Masses: A Microsimulation-Based Decision Analysis. AJR Am J Roentgenol 2016. PubMed
  • Harvey HB, Alkasab TK, Prabhakar AM, Halpern EF, Rosenthal DI, Pandharipande PV, Gazelle GS. Radiologist Peer Review by Group Consensus. J Am Coll Radiol 2016. PubMed
  • Pandharipande PV, Heberle C, Dowling EC, Kong CY, Tramontano A, Perzan KE, Brugge W, Hur C. Targeted Screening of Individuals at High Risk for Pancreatic Cancer: Results of a Simulation Model. Radiology 2015; 278:306. PubMed
  • Lu MT, Rosman DA, Wu CC, Gilman MD, Harvey HB, Gervais DA, Alkasab TK, Shepard JO, Boland GW, Pandharipande PV. Radiologist Point-of-Care Clinical Decision Support and Adherence to Guidelines for Incidental Lung Nodules. J Am Coll Radiol 2015. PubMed
  • Harvey HB, Alkasab TK, Pandharipande PV, Halpern EF, Prabhakar AM, Oklu R, Rosenthal DI, Hirsch JA, Gazelle GS, Brink JA. Non-Research-Related Physician-Industry Relationships of Radiologists in the United States. J Am Coll Radiol 2015. PubMed
  • Harvey HB, Tomov E, Babayan A, Dwyer K, Boland S, Pandharipande PV, Halpern EF, Alkasab TK, Hirsch JA, Schaefer PW, Boland GW, Choy G. Radiology Malpractice Claims in the United States From 2008 to 2012: Characteristics and Implications. J Am Coll Radiol 2015. PubMed
  • Glover M, Khalilzadeh O, Choy G, Prabhakar AM, Pandharipande PV, Gazelle GS. Hospital Evaluations by Social Media: A Comparative Analysis of Facebook Ratings among Performance Outliers. J Gen Intern Med 2015. PubMed
  • Pandharipande PV, Reisner AT, Binder WD, Zaheer A, Gunn ML, Linnau KF, Miller CM, Avery LL, Herring MS, Tramontano AC, Dowling EC, Abujudeh HH, Eisenberg JD, Halpern EF, Donelan K, Gazelle GS. CT in the Emergency Department: A Real-Time Study of Changes in Physician Decision Making. Radiology 2015. PubMed
  • Lightfoote JB, Fielding JR, Deville C, Gunderman RB, Morgan GN, Pandharipande PV, Duerinckx AJ, Wynn RB, Macura KJ. Counterpoint: Diversity and Inclusion: Works in Progress. J Am Coll Radiol 2015. PubMed
  • Pandharipande PV, Heberle C, Dowling EC, Kong CY, Tramontano A, Perzan KE, Brugge W, Hur C. Targeted screening of individuals at high risk for pancreatic cancer: results of a simulation model. Radiology 2015; 275:177-87. PubMed
  • Harvey HB, Gilman MD, Wu CC, Cushing MS, Halpern EF, Zhao J, Pandharipande PV, Shepard JA, Alkasab TK. Diagnostic yield of recommendations for chest CT examination prompted by outpatient chest radiographic findings. Radiology 2015; 275:262-71. PubMed
  • Harvey HB, Alkasab TK, Pandharipande PV, Zhao J, Halpern EF, Salazar GM, Abujudeh HH, Rosenthal DI, Gazelle GS. Radiologist compliance with institutional guidelines for use of nonroutine communication of diagnostic imaging results. J Am Coll Radiol 2015; 12:376-84. PubMed
  • Eisenberg JD, Gervais DA, Singh S, Kalra MK, Sabir SH, Paul AB, Pandharipande PV. Radiation exposure from CT-guided ablation of renal masses: effects on life expectancy. AJR Am J Roentgenol 2015; 204:335-42. PubMed
  • Kang SK, Turan EA, Eisenberg JD, Lee PA, Kong CY, Pandharipande PV. Microsimulation model of CT versus MRI surveillance of Bosniak IIF renal cystic lesions: should effects of radiation exposure affect selection of imaging strategy? AJR Am J Roentgenol 2014; 203:W629-36. PubMed
  • Lam DL, Pandharipande PV, Lee JM, Lehman CD, Lee CI. Imaging-based screening: understanding the controversies. AJR Am J Roentgenol 2014; 203:952-6. PubMed
  • Kiatpongsan S, Meng L, Eisenberg JD, Herring M, Avery LL, Kong CY, Pandharipande PV. Imaging for appendicitis: should radiation-induced cancer risks affect modality selection? Radiology 2014; 273:472-82. PubMed
  • Kang SK, Huang WC, Pandharipande PV, Chandarana H. Solid renal masses: what the numbers tell us. AJR Am J Roentgenol 2014; 202:1196-206. PubMed
  • Eisenberg JD, Gilmore ME, Kalra MK, Kong CY, Pandharipande PV. Prioritizing examination-centered over patient-centered dose reduction: a hazard of institutional "benchmarking". AJR Am J Roentgenol 2014; 202:1062-8. PubMed
  • Goske MJ, Frush DP, Brink JA, Kaste SC, Butler PF, Pandharipande PV. Curbing potential radiation-induced cancer risks in oncologic imaging: perspectives from the 'image gently' and 'image wisely' campaigns. Oncology (Huntingt) 2014; 28:232-8, 243. PubMed
  • Eisenberg JD, Lewin SO, Pandharipande PV. The fisherman's cards: how to address past and future radiation exposures in clinical decision making. AJR Am J Roentgenol 2014; 202:362-7. PubMed
  • Harvey HB, Gowda V, Gazelle GS, Pandharipande PV. The ephemeral accountable care organization-an unintended consequence of the Medicare shared savings program. J Am Coll Radiol 2014; 11:121-4. PubMed
  • Mitchell DG, Javitt MC, Glanc P, Bennett GL, Brown DL, Dubinsky T, Harisinghani MG, Harris RD, Horowitz NS, Pandharipande PV, Pannu HK, Podrasky AE, Royal HD, Shipp TD, Siegel CL, Simpson L, Wong-You-Cheong JJ, Zelop CM, . ACR appropriateness criteria staging and follow-up of ovarian cancer. J Am Coll Radiol 2013; 10:822-7. PubMed
  • Pandharipande PV, Eisenberg JD, Avery LL, Gunn ML, Kang SK, Megibow AJ, Turan EA, Harvey HB, Kong CY, Dowling EC, Halpern EF, Donelan K, Gazelle GS. Journal club: How radiation exposure histories influence physician imaging decisions: a multicenter radiologist survey study. AJR Am J Roentgenol 2013; 200:1275-83. PubMed
  • Pandharipande PV, Eisenberg JD, Lee RJ, Gilmore ME, Turan EA, Singh S, Kalra MK, Liu B, Kong CY, Gazelle GS. Patients with testicular cancer undergoing CT surveillance demonstrate a pitfall of radiation-induced cancer risk estimates: the timing paradox. Radiology 2013; 266:896-904. PubMed
  • Harris RD, Javitt MC, Glanc P, Brown DL, Dubinsky T, Harisinghani MG, Khati NJ, Kim YB, Mitchell DG, Pandharipande PV, Pannu HK, Podrasky AE, Royal HD, Shipp TD, Siegel CL, Simpson L, Wall DJ, Wong-You-Cheong JJ, Zelop CM, . ACR Appropriateness Criteria® clinically suspected adnexal mass. Ultrasound Q 2013; 29:79-86. PubMed
  • Hartman RI, Chang CY, Wo JY, Eisenberg JD, Hong TS, Harisinghani MG, Gazelle GS, Pandharipande PV. Optimizing adjuvant treatment decisions for stage t2 rectal cancer based on mesorectal node size: a decision analysis. Acad Radiol 2012. PubMed
  • Eisenberg JD, Harvey HB, Moore DA, Gazelle GS, Pandharipande PV. Falling prey to the sunk cost bias: a potential harm of patient radiation dose histories. Radiology 2012; 263:626-8. PubMed
  • Kong CY, Lee JM, McMahon PM, Lowry KP, Omer ZB, Eisenberg JD, Pandharipande PV, Gazelle GS. Using radiation risk models in cancer screening simulations: important assumptions and effects on outcome projections. Radiology 2012; 262:977-84. PubMed
  • Rutter CM, Knudsen AB, Pandharipande PV. Computer disease simulation models: integrating evidence for health policy. Acad Radiol 2011; 18:1077-86. PubMed
  • Ding A, Eisenberg JD, Pandharipande PV. The economic burden of incidentally detected findings. Radiol Clin North Am 2011; 49:257-65. PubMed
  • Pandharipande PV, Gervais DA, Hartman RI, Harisinghani MG, Feldman AS, Mueller PR, Gazelle GS. Renal mass biopsy to guide treatment decisions for small incidental renal tumors: a cost-effectiveness analysis. Radiology 2010; 256:836-46. PubMed
  • Pandharipande PV, Gazelle GS. Comparative effectiveness research: what it means for radiology. Radiology 2009; 253:600-5. PubMed
  • Pandharipande PV, Mora JT, Uppot RN, Goehler A, Braschi M, Halpern EF, Gazelle GS, Harisinghani MG. Lymphotropic nanoparticle-enhanced MRI for independent prediction of lymph node malignancy: a logistic regression model. AJR Am J Roentgenol 2009; 193:W230-7. PubMed
  • Pandharipande PV,Choy G,del Carmen MG,Gazelle GS,Russell AH,Lee SI. MRI and PET/CT for triaging stage IB clinically operable cervical cancer to appropriate therapy: decision analysis to assess patient outcomes. AJR Am J Roentgenol 2009; 192:802-14. PubMed
  • Pandharipande PV,Harisinghani MG,Ozanne EM,Specht MC,Hur C,Lee JM,Gazelle GS. Staging MR lymphangiography of the axilla for early breast cancer: cost-effectiveness analysis. AJR Am J Roentgenol 2008; 191:1308-19. PubMed
  • Pandharipande PV, Gervais DA, Mueller PR, Hur C, Gazelle GS. Radiofrequency Ablation versus Nephron-sparing Surgery for Small Unilateral Renal Cell Carcinoma: Cost-effectiveness Analysis. Radiology 2008; 248:169-78. PubMed
  • Rodr. Implications and cost of pancreatic leak following distal pancreatic resection. Arch Surg 2006; 141:361-5; discussion 366. PubMed
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