I am the Director of GI Pathology Division at Brigham and Women's Hospital and Professor of Pathology at Harvard Medical School. My main research interests include the pathology, pathogenesis, natural history, and molecular biology of cancer development in chronic inflammatory conditions of the GI tract - most notably Barrett's esophagus and inflammatory bowel disease. This research focuses on the mechanisms of progression from chronic inflammation through various grades of dysplasia to adenocarcinoma. Other research interests include laboratory and animal research on the mechanisms involved in inflammation, and in the development, of Barrett's esophagus in patients with gastroesophageal reflux disease. I collaborate with a number of basic research laboratories, and with clinical services from other widely acclaimed institutes in America and in Europe. I have authored more than 300 peer reviewed research papers, reviews, editorials, and book chapters. I am the senior editor of the largest most comprehensive textbook of GI pathology titled "Surgical Pathology of the GI Tract and the Biliary tract and Pancreas"