Photo of Robert S. Stern,  MD

Robert S. Stern, MD

Beth Israel Deaconess Medical Center

Beth Israel Deaconess Medical Center
Phone: (617) 667-4995
Fax: (617) 667-4948


rstern@bidmc.harvard.edu

Robert S. Stern, MD

Beth Israel Deaconess Medical Center

EDUCATIONAL TITLES

  • Carl J. Herzog Professor of Dermatologly, Dermatology, Harvard Medical School
  • Chairman, Dermatology, Beth Israel Deaconess Medical Center

DF/HCC PROGRAM AFFILIATION

Research Abstract

My clinical research interests include the epidemiology of both melanoma and non-melanoma skin cancer and the treatment of skin cancer, particularly non-melanoma skin cancer. I am also involved in the treatment of cutaneous T-cell lymphoma and its precursors. In addition, I participate in teaching and patient care related to the above topics.

Publications

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  • Wu PA, Stern RS. How likely is another nonmelanoma skin cancer?: better informing patients and clinicians. JAMA Dermatol 2015; 151:369-70. PubMed
  • Stern RS. Cost effectiveness of mohs micrographic surgery. J Invest Dermatol 2013; 133:1129-31. PubMed
  • Roujeau JC, Mockenhaupt M, Tahan SR, Henshaw J, Martin EC, Harding M, van Baelen B, Bengtsson L, Singhal P, Kauffman RS, Stern RS. Telaprevir-Related Dermatitis. Arch Dermatol 2012. PubMed
  • Curiel-Lewandrowski C, Nijsten T, Gomez ML, Hollestein LM, Atkins MB, Stern RS. Long-Term Use of Nonsteroidal Anti-inflammatory Drugs Decreases the Risk of Cutaneous Melanoma: Results of a United States Case-Control Study. J Invest Dermatol 2011. PubMed
  • Stern RS. Poor metrics and lost opportunity. J Am Acad Dermatol 2010; 63:718-9. PubMed
  • Stern RS. Prevalence of a history of skin cancer in 2007: results of an incidence-based model. Arch Dermatol 2010; 146:279-82. PubMed
  • Stern RS. Putting Iatrogenic Risk in Perspective: Basal Cell Cancer in PUVA Patients and Australians. J Invest Dermatol 2009; 129:2315-6. PubMed
  • Nijsten T,Spuls P,Stern RS. STROBE: a Beacon for observational studies. Arch Dermatol 2008; 144:1200-4. PubMed
  • Martin DC, Atmuri V, Hemming RJ, Farley J, Mort JS, Byers S, Hombach-Klonisch S, Stern R, Triggs-Raine BL. A mouse model of human Mucopolysaccharidosis IX exhibits osteoarthritis. Hum Mol Genet 2008; 17:1904-15. PubMed
  • Hubbard EJ, Santini V, Blankevoort CG, Volkers KM, Barrup MS, Byerly L, Chaisson C, Jefferson AL, Kaplan E, Green RC, Stern RA. Clock drawing performance in cognitively normal elderly. Arch Clin Neuropsychol 2008; 23:295-327. PubMed
  • Stern R, Maibach HI. Hyaluronan in skin: aspects of aging and its pharmacologic modulation. Clin Dermatol 2008; 26:106-22. PubMed
  • Ashendorf L, Jefferson AL, O'Connor MK, Chaisson C, Green RC, Stern RA. Trail Making Test errors in normal aging, mild cognitive impairment, and dementia. Arch Clin Neuropsychol 2008; 23:129-37. PubMed
  • Posternak M, Novak S, Stern R, Hennessey J, Joffe R, Prange A Jr, Zimmerman M. A pilot effectiveness study: placebo-controlled trial of adjunctive L-triiodothyronine (T3) used to accelerate and potentiate the antidepressant response. Int J Neuropsychopharmacol 2007; 11:15-25. PubMed
  • Karagas MR, Stukel TA, Umland V, Tsoukas MM, Mott LA, Sorensen HT, Jensen AO, Nelson HH, Spencer SK, Perry AE, Stern RS. Reported use of photosensitizing medications and basal cell and squamous cell carcinoma of the skin: results of a population-based case-control study. J Invest Dermatol 2007; 127:2901-3. PubMed
  • Stern RS. Chronic medication use and inflammatory skin diseases: the power and limitations of the case-control study. J Invest Dermatol 2007; 127:2709-10. PubMed
  • Pirmohamed M, Arbuckle JB, Bowman CE, Brunner M, Burns DK, Delrieu O, Dix LP, Twomey JA, Stern RS. Investigation into the multidimensional genetic basis of drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis. Pharmacogenomics 2007; 8:1661-91. PubMed
  • Stern R, Kogan G, Jedrzejas MJ, Soltes L. The many ways to cleave hyaluronan. Biotechnol Adv 2007; 25:537-57. PubMed
  • Nijsten T, Looman CW, Stern RS. Clinical severity of psoriasis in last 20 years of PUVA study. Arch Dermatol 2007; 143:1113-21. PubMed
  • Stern RS. Psoralen and ultraviolet a light therapy for psoriasis. N Engl J Med 2007; 357:682-90. PubMed
  • Malanos D, Stern RS. Psoralen plus ultraviolet A does not increase the risk of cataracts: a 25-year prospective study. J Am Acad Dermatol 2007; 57:231-7. PubMed
  • Jones-Caballero M, Unaeze J, Penas PF, Stern RS. Use of biological agents in patients with moderate to severe psoriasis: a cohort-based perspective. Arch Dermatol 2007; 143:846-50. PubMed
  • Nijsten TE, Stern RS. The increased risk of skin cancer is persistent after discontinuation of psoralen+ultraviolet A: a cohort study. J Invest Dermatol 2003; 121:252-8. PubMed
  • Stern RS. Assessing the safety of immunologic modifiers for the treatment of chronic disease: the psoriasis paradigm. J Invest Dermatol 2003; 120:xi-xii. PubMed
  • Stern RS. Actinic degeneration and pigmentary change in association with psoralen and UVA treatment: a 20-year prospective study. J Am Acad Dermatol 2003; 48:61-7. PubMed
  • Shuster S, Frost GI, Csoka AB, Formby B, Stern R. Hyaluronidase reduces human breast cancer xenografts in SCID mice. Int J Cancer 2002; 102:192-7. PubMed
  • Stern RS, Bolshakov S, Nataraj AJ, Ananthaswamy HN. p53 mutation in nonmelanoma skin cancers occurring in psoralen ultraviolet a-treated patients: evidence for heterogeneity and field cancerization. J Invest Dermatol 2002; 119:522-6. PubMed
  • Nijsten TE, Stern RS. Genital squamous cell carcinoma in men treated by photochemotherapy. A cancer registry-based study from 1978 to 1998. Br J Dermatol 2002; 147:184-5; author reply 185-6. PubMed
  • Katz KA, Marcil I, Stern RS. Incidence and risk factors associated with a second squamous cell carcinoma or basal cell carcinoma in psoralen + ultraviolet a light-treated psoriasis patients. J Invest Dermatol 2002; 118:1038-43. PubMed
  • Marcil I, Stern RS. Squamous-cell cancer of the skin in patients given PUVA and ciclosporin: nested cohort crossover study. Lancet 2001; 358:1042-5. PubMed
  • Lin G, Stern R. Plasma hyaluronidase (Hyal-1) promotes tumor cell cycling. Cancer Lett 2001; 163:95-101. PubMed
  • Marcil I, Stern RS. Risk of developing a subsequent nonmelanoma skin cancer in patients with a history of nonmelanoma skin cancer: a critical review of the literature and meta-analysis. Arch Dermatol 2000; 136:1524-30. PubMed
  • Lindel. Incidence of skin cancer in 5356 patients following organ transplantation. Br J Dermatol 2000; 143:513-9. PubMed
  • Morrow GR, Andrews PL, Hickok JT, Stern R. Vagal changes following cancer chemotherapy: implications for the development of nausea. Psychophysiology 2000; 37:378-84. PubMed
  • Meyer LJ, Russell SB, Russell JD, Trupin JS, Egbert BM, Shuster S, Stern R. Reduced hyaluronan in keloid tissue and cultured keloid fibroblasts. J Invest Dermatol 2000; 114:953-9. PubMed
  • Frost GI, Mohapatra G, Wong TM, Cs. HYAL1LUCA-1, a candidate tumor suppressor gene on chromosome 3p21.3, is inactivated in head and neck squamous cell carcinomas by aberrant splicing of pre-mRNA. Oncogene 2000; 19:870-7. PubMed
  • Baron ED, Stern RS, Taylor CR. Correlating skin type and minimum erythema dose. Arch Dermatol 1999; 135:1278-9. PubMed
  • Stern RS. The mysteries of geographic variability in nonmelanoma skin cancer incidence. Arch Dermatol 1999; 135:843-4. PubMed
  • Rzany B, Correia O, Kelly JP, Naldi L, Auquier A, Stern R. Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis during first weeks of antiepileptic therapy: a case-control study. Study Group of the International Case Control Study on Severe Cutaneous Adverse Reactions. Lancet 1999; 353:2190-4. PubMed
  • Stern RS. Malignant melanoma in patients treated for psoriasis with PUVA. Photodermatol Photoimmunol Photomed 1999; 15:37-8. PubMed
  • Stern RS, Lunder EJ. Risk of squamous cell carcinoma and methoxsalen (psoralen) and UV-A radiation (PUVA). A meta-analysis. Arch Dermatol 1999; 134:1582-5. PubMed
  • Lunder EJ, Stern RS. Merkel-cell carcinomas in patients treated with methoxsalen and ultraviolet A radiation. N Engl J Med 1998; 339:1247-8. PubMed
  • Stern RS, Liebman EJ, V. Oral psoralen and ultraviolet-A light (PUVA) treatment of psoriasis and persistent risk of nonmelanoma skin cancer. PUVA Follow-up Study. J Natl Cancer Inst 1998; 90:1278-84. PubMed
  • Tennis P, Stern RS. Risk of serious cutaneous disorders after initiation of use of phenytoin, carbamazepine, or sodium valproate: a record linkage study. Neurology 1997; 49:542-6. PubMed
  • Stern RS, V. Noncutaneous malignant tumors in the PUVA follow-up study: 1975-1996. J Invest Dermatol 1997; 108:897-900. PubMed
  • Stern RS, Nichols KT, V. Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). The PUVA Follow-Up Study. N Engl J Med 1997; 336:1041-5. PubMed
  • McKenna KE, Stern RS. The impact of psoriasis on the quality of life of patients from the 16-center PUVA follow-up cohort. J Am Acad Dermatol 1997; 36:388-94. PubMed
  • Goyal S, Arndt KA, Stern RS, O'Hare D, Dover JS. Laser treatment of tattoos: a prospective, paired, comparison study of the Q-switched Nd:YAG (1064 nm), frequency-doubled Q-switched Nd:YAG (532 nm), and Q-switched ruby lasers. J Am Acad Dermatol 1997; 36:122-5. PubMed
  • Stern RS, Nichols KT. Therapy with orally administered methoxsalen and ultraviolet A radiation during childhood increases the risk of basal cell carcinoma. The PUVA Follow-up Study. J Pediatr 1996; 129:915-7. PubMed
  • Stern RS. Managed care and the treatment of skin diseases. Dermatologists do it less often. Arch Dermatol 1996; 132:1039-42. PubMed
  • Stern RS. Acne therapy. Medication use and sources of care in office-based practice. Arch Dermatol 1996; 132:776-80. PubMed
  • Coopman SA, Johnson RA, Platt R, Stern RS. Cutaneous disease and drug reactions in HIV infection. N Engl J Med 1993; 328:1670-4. PubMed
  • Stern RS, Scotto J, Fears TR. Psoriasis and susceptibility to nonmelanoma skin cancer. J Am Acad Dermatol 1984; 12:67-73. PubMed
  • Kopf AW, Kripke ML, Stern RS. Sun and malignant melanoma. J Am Acad Dermatol 1984; 11:674-84. PubMed
  • Stern RS, Bigby M. An expanded profile of cutaneous reactions to nonsteroidal anti-inflammatory drugs. Reports to a specialty-based system for spontaneous reporting of adverse reactions to drugs. JAMA 1984; 252:1433-7. PubMed
  • Paul BS, Momtaz K, Stern RS, Arndt KA, Parrish JA. Combined methotrexate--ultraviolet B therapy in the treatment of psoriasis. J Am Acad Dermatol 1982; 7:758-62. PubMed
  • Stern RS, Zierler S, Parrish JA. Skin carcinoma in patients with psoriasis treated with topical tar and artificial ultraviolet radiation. Lancet 1980; 1:732-5. PubMed
  • Stern RS, Thibodeau LA, Kleinerman RA, Parrish JA, Fitzpatrick TB. Risk of cutaneous carcinoma in patients treated with oral methoxsalen photochemotherapy for psoriasis. N Engl J Med 1979; 300:809-13. PubMed
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