Photo of Rosemary Tambouret,  MD

Rosemary Tambouret, MD

Massachusetts General Hospital

Massachusetts General Hospital
Phone: (617) 724-3862
Fax: (617) 724-6564


rtambouret@partners.org

Rosemary Tambouret, MD

Massachusetts General Hospital

EDUCATIONAL TITLES

  • Assistant Professor, Pathology, Harvard Medical School
  • Assistant in Pathology, Pathology, Massachusetts General Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

My current research involves the evaluation of the enhancement of cervical cytology screening by application of an immunocytochemical stain containing antibodies with specificity for topoisomerase 2a and for minichromosome maintenance 5 protein. I am also working on evaluation of the effect of senescence on cells in cervical cytology specimens by the use of beta-galactosidase reaction.

Publications

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  • Crothers BA, Darragh TM, Tambouret RH, Nayar R, Barkan GA, Zhao C, Booth CN, Padmanabhan V, Tabatabai ZL, Souers RJ, Thomas N, Wilbur DC, Moriarty AT. Trends in Cervical Cytology Screening and Reporting Practices: Results From the College of American Pathologists 2011 PAP Education Supplemental Questionnaire. Arch Pathol Lab Med 2015. PubMed
  • Growdon WB, Groeneweg J, Byron V, DiGloria C, Borger DR, Tambouret R, Foster R, Chenna A, Sperinde J, Winslow J, Rueda BR. HER2 over-expressing high grade endometrial cancer expresses high levels of p95HER2 variant. Gynecol Oncol 2015; 137:160-6. PubMed
  • Zhao C, Moriarty AT, Ghofrani M, Husain M, Tambouret RH, Laucirica R, Laser A, Fischer A, Ocal IT, Souers RJ, Russell DK, Fan F, Crothers BA. Human Papillomavirus Testing and Reporting Rates in 2012: Results of a College of American Pathologists' National Survey. Arch Pathol Lab Med 2014. PubMed
  • Groeneweg JW, Hernandez SF, Byron VF, DiGloria CM, Lopez H, Scialabba V, Kim M, Zhang L, Borger DR, Tambouret R, Foster R, Rueda BR, Growdon WB. Dual HER2 Targeting Impedes Growth of HER2 Gene Amplified Uterine Serous Carcinoma Xenografts. Clin Cancer Res 2014. PubMed
  • Groeneweg JW, Hall TR, Zhang L, Kim M, Byron VF, Tambouret R, Sathayanrayanan S, Foster R, Rueda BR, Growdon WB. Inhibition of gamma-secretase activity impedes uterine serous carcinoma growth in a human xenograft model. Gynecol Oncol 2014. PubMed
  • Guseh SH, Rauh-Hain JA, Tambouret RH, Davis M, Clark RM, Boruta DM, Goodman A, Growdon WB, Schorge JO, del Carmen MG. Transitional cell carcinoma of the ovary: a case-control study. Gynecol Oncol 2014; 132:649-53. PubMed
  • Evans KK, Georgian-Smith D, Tambouret R, Birdwell RL, Wolfe JM. The gist of the abnormal: above-chance medical decision making in the blink of an eye. Psychon Bull Rev 2013; 20:1170-5. PubMed
  • Chebib I, Rao RA, Wilbur DC, Tambouret RH. Using the ASC:SIL ratio, human papillomavirus, and interobserver variability to assess and monitor cytopathology fellow training performance. Cancer Cytopathol 2014; 121:638-43. PubMed
  • Auger M, Nayar R, Khalbuss WE, Barkan GA, Benedict CC, Tambouret R, Schwartz MR, Howell LP, Souers RJ, Hartley DA, Thomas N, Moriarty AT. Implementation of the Bethesda System for Reporting Thyroid Cytopathology: observations from the 2011 thyroid supplemental questionnaire of the College of American Pathologists. Arch Pathol Lab Med 2013; 137:1555-9. PubMed
  • Tambouret RH. The evolution of the Papanicolaou smear. Clin Obstet Gynecol 2013; 56:3-9. PubMed
  • Nishino HT, Wilbur DC, Tambouret RH. Low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion: a category with an increased outcome of high-grade lesions: use as a quality assurance measure. Am J Clin Pathol 2012; 138:198-202. PubMed
  • Growdon WB, Roussel BN, Scialabba VL, Foster R, Dias-Santagata D, Iafrate AJ, Ellisen LW, Tambouret RH, Rueda BR, Borger DR. Tissue-specific signatures of activating PIK3CA and RAS mutations in carcinosarcomas of gynecologic origin. Gynecol Oncol 2011; 121:212-7. PubMed
  • Ferriss JS, Brix W, Tambouret R, DeSimone CP, Stoler M, Modesitt SC. Cervical stromal invasion predicting survival in endometrial cancer. Obstet Gynecol 2010; 116:1035-41. PubMed
  • Etit D, Selig M, Faquin WC, Pitman MB, Tambouret RH, Misdraji J, Petur Nielsen G. The utility of electron microscopy in cytopathology. Ultrastruct Pathol 2010; 34:252-9. PubMed
  • Fischer AH, Zhao C, Li QK, Gustafson KS, Eltoum IE, Tambouret R, Benstein B, Savaloja LC, Kulesza P. The cytologic criteria of malignancy. J Cell Biochem 2010; 110:795-811. PubMed
  • Young RH, Goodman A, Penson RT, Russell AH, Uppot RN, Tambouret RH. Case records of the Massachusetts General Hospital. Case 8-2010. A 22-year-old woman with hypercalcemia and a pelvic mass. N Engl J Med 2010; 362:1031-40. PubMed
  • Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, Pitman MB, Rosenberg AE, Smith RN, Sohani AR, Stone JR, Tambouret RH, Wu CL, Young RH, Zembowicz A, Klietmann W. Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. Arch Pathol Lab Med 2009; 133:1949-53. PubMed
  • Sauder K,Wilbur DC,Duska L,Tambouret RH. An approach to post-radical trachelectomy vaginal-isthmus cytology. Diagn Cytopathol 2009; 37:437-42. PubMed
  • Olawaiye A,Del Carmen M,Tambouret R,Goodman A,Fuller A,Duska LR. Abdominal radical trachelectomy: Success and pitfalls in a general gynecologic oncology practice. Gynecol Oncol 2009; 112:506-10. PubMed
  • Tambouret RH. [Diagnostic importance of ProEx C in gynecologic cytopathology] Ann Pathol 2008; 28 Spec No 1:S92-3. PubMed
  • Kirkham JC,Nero CJ,Tambouret RH,Yoon SS. Leiomyoma and leiomyosarcoma arising from the round ligament of the uterus. J Am Coll Surg 2008; 207:452. PubMed
  • Tambouret RH,Misdraji J,Wilbur DC. Longitudinal clinical evaluation of a novel antibody cocktail for detection of high-grade squamous intraepithelial lesions on cervical cytology specimens. Arch Pathol Lab Med 2008; 132:918-25. PubMed
  • Belsley NA, Tambouret RH, Misdraji J, Muzikansky A, Russell DK, Wilbur DC. Cytologic features of endocervical glandular lesions: comparison of SurePath, ThinPrep, and conventional smear specimen preparations. Diagn Cytopathol 2008; 36:232-7. PubMed
  • Ko V, Nanji S, Tambouret RH, Wilbur DC. Testing for HPV as an objective measure for quality assurance in gynecologic cytology: positive rates in equivocal and abnormal specimens and comparison with the ASCUS to SIL ratio. Cancer 2007; 111:67-73. PubMed
  • Ko V, Tambouret RH, Kuebler DL, Black-Schaffer WS, Wilbur DC. Human papillomavirus testing using hybrid capture II with SurePath collection: initial evaluation and longitudinal data provide clinical validation for this method. Cancer 2006; 108:468-74. PubMed
  • Misdraji J, Vaidya A, Tambouret RH, Duska L, Bell DA. Psammoma bodies in cervicovaginal cytology specimens: A clinicopathological analysis of 31 cases. Gynecol Oncol 2006; 103:238-46. PubMed
  • Tambouret RH, Wilbur DC. The many faces of atrophy in gynecologic cytology. Clin Lab Med 2003; 23:659-79. PubMed
  • Tambouret R, Clement PB, Young RH. Endometrial endometrioid adenocarcinoma with a deceptive pattern of spread to the uterine cervix: a manifestation of stage IIb endometrial carcinoma liable to be misinterpreted as an independent carcinoma or a benign lesion. Am J Surg Pathol 2003; 27:1080-8. PubMed
  • Brogi E, Tambouret R, Bell DA. Classification of benign endometrial glandular cells in cervical smears from postmenopausal women. Cancer 2002; 96:60-6. PubMed
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