Photo of Ross Berbeco,  PhD

Ross Berbeco, PhD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 525-7136


rberbeco@lroc.harvard.edu

Ross Berbeco, PhD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Associate Professor, Radiation Oncology, Harvard Medical School
  • Staff Physicist, Radiation Oncology, Brigham And Women's Hospital
  • Staff Physicist, Radiation Oncology, Dana-Farber Cancer Institute

DF/HCC PROGRAM AFFILIATION

Publications

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  • Cai W, Hurwitz MH, Williams CL, Dhou S, Berbeco RI, Seco J, Mishra P, Lewis JH. 3D delivered dose assessment using a 4DCT-based motion model. Med Phys 2015; 42:2897. PubMed
  • Altundal Y, Cifter G, Detappe A, Sajo E, Tsiamas P, Zygmanski P, Berbeco R, Cormack RA, Makrigiorgos M, Ngwa W. New potential for enhancing concomitant chemoradiotherapy with FDA approved concentrations of cisplatin via the photoelectric effect. 2015; 31:25-30. PubMed
  • Bryant JH, Rottmann J, Lewis JH, Mishra P, Keall PJ, Berbeco RI. Registration of clinical volumes to beams-eye-view images for real-time tracking. Med Phys 2014; 41:121703. PubMed
  • Rottmann J, Berbeco R. Using an external surrogate for predictor model training in real-time motion management of lung tumors. Med Phys 2014; 41:121706. PubMed
  • Yip S, Chen AB, Aerts HJ, Berbeco R. Sensitivity study of voxel-based PET image comparison to image registration algorithms. Med Phys 2014; 41:111714. PubMed
  • Mishra P, Li R, Mak RH, Rottmann J, Bryant JH, Williams CL, Berbeco RI, Lewis JH. An initial study on the estimation of time-varying volumetric treatment images and 3D tumor localization from single MV cine EPID images. Med Phys 2014; 41:081713. PubMed
  • Luchette M, Korideck H, Makrigiorgos M, Tillement O, Berbeco R. Radiation dose enhancement of gadolinium-based AGuIX nanoparticles on HeLa cells. 2014. PubMed
  • Yip S, Rottmann J, Berbeco R. The impact of cine EPID image acquisition frame rate on markerless soft-tissue tracking. Med Phys 2014; 41:061702. PubMed
  • Jensen C, Urribarri J, Cail D, Rottmann J, Mishra P, Lingos T, Niedermayr T, Berbeco R. Cine EPID evaluation of two non-commercial techniques for DIBH. Med Phys 2014; 41:021730. PubMed
  • Herter-Sprie GS, Korideck H, Christensen CL, Herter JM, Rhee K, Berbeco RI, Bennett DG, Akbay EA, Kozono D, Mak RH, Mike Makrigiorgos G, Kimmelman AC, Wong KK. Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models. Nat Commun 2014; 5:5870. PubMed
  • Yip S, McCall K, Aristophanous M, Chen AB, Aerts HJ, Berbeco R. Comparison of texture features derived from static and respiratory-gated PET images in non-small cell lung cancer. PLoS ONE 2014; 9:e115510. PubMed
  • Rottmann J, Keall P, Berbeco R. Real-time soft tissue motion estimation for lung tumors during radiotherapy delivery. Med Phys 2013; 40:091713. PubMed
  • Kumar R, Korideck H, Ngwa W, Berbeco RI, Makrigiorgos GM, Sridhar S. Third generation gold nanoplatform optimized for radiation therapy. Transl Cancer Res 2014. PubMed
  • Williams CL, Mishra P, Seco J, St James S, Mak RH, Berbeco RI, Lewis JH. A mass-conserving 4D XCAT phantom for dose calculation and accumulation. Med Phys 2013; 40:071728. PubMed
  • Detappe A, Tsiamas P, Ngwa W, Zygmanski P, Makrigiorgos M, Berbeco R. The effect of flattening filter free delivery on endothelial dose enhancement with gold nanoparticles. Med Phys 2013; 40:031706. PubMed
  • Mishra P, Li R, James SS, Mak RH, Williams CL, Yue Y, Berbeco RI, Lewis JH. Evaluation of 3D fluoroscopic image generation from a single planar treatment image on patient data with a modified XCAT phantom. Phys Med Biol 2013; 58:841-58. PubMed
  • Tsiamas P, Liu B, Cifter F, Ngwa WF, Berbeco RI, Kappas C, Theodorou K, Marcus K, Makrigiorgos MG, Sajo E, Zygmanski P. Impact of beam quality on megavoltage radiotherapy treatment techniques utilizing gold nanoparticles for dose enhancement. Phys Med Biol 2013; 58:451-64. PubMed
  • Zygmanski P, Hoegele W, Tsiamas P, Cifter F, Ngwa W, Berbeco R, Makrigiorgos M, Sajo E. A stochastic model of cell survival for high-Z nanoparticle radiotherapy. Med Phys 2013; 40:024102. PubMed
  • Berbeco RI, Korideck H, Ngwa W, Kumar R, Patel J, Sridhar S, Johnson S, Price BD, Kimmelman A, Makrigiorgos GM. DNA Damage Enhancement from Gold Nanoparticles for Clinical MV Photon Beams. Radiat Res 2012. PubMed
  • Ngwa W, Makrigiorgos GM, Berbeco RI. Gold nanoparticle enhancement of stereotactic radiosurgery for neovascular age-related macular degeneration. Phys Med Biol 2012; 57:6371-80. PubMed
  • Li R, Lewis JH, Berbeco RI, Xing L. Real-time tumor motion estimation using respiratory surrogate via memory-based learning. Phys Med Biol 2012; 57:4771-86. PubMed
  • Mishra P, St James S, Segars WP, Berbeco RI, Lewis JH. Adaptation and applications of a realistic digital phantom based on patient lung tumor trajectories. Phys Med Biol 2012; 57:3597-608. PubMed
  • Ren Q, Nishioka S, Shirato H, Berbeco R. Adaptive external gating based on the updating method of internal/external correlation and gating window before each beam delivery. Phys Med Biol 2012; 57:N145-57. PubMed
  • Ngwa W, Tsiamas P, Zygmanski P, Makrigiorgos GM, Berbeco RI. A multipurpose quality assurance phantom for the small animal radiation research platform (SARRP). Phys Med Biol 2012; 57:2575-86. PubMed
  • James SS, Mishra P, Hacker F, Berbeco RI, Lewis JH. Quantifying ITV instabilities arising from 4DCT: a simulation study using patient data. Phys Med Biol 2012; 57:L1-7. PubMed
  • Aristophanous M, Yong Y, Yap JT, Killoran JH, Allen AM, Berbeco RI, Chen AB. Evaluating FDG uptake changes between pre and post therapy respiratory gated PET scans. Radiother Oncol 2012; 102:377-82. PubMed
  • Ngwa W, Makrigiorgos GM, Berbeco RI. Gold nanoparticle-aided brachytherapy with vascular dose painting: estimation of dose enhancement to the tumor endothelial cell nucleus. Med Phys 2012; 39:392-8. PubMed
  • Ngwa W, Korideck H, Chin LM, Makrigiorgos GM, Berbeco RI. MOSFET Assessment of Radiation Dose Delivered to Mice Using the Small Animal Radiation Research Platform (SARRP). Radiat Res 2011. PubMed
  • Yue Y, Aristophanous M, Rottmann J, Berbeco RI. 3-D fiducial motion tracking using limited MV projections in arc therapy. Med Phys 2011; 38:3222-31. PubMed
  • Glide-Hurst CK, Ionascu D, Berbeco R, Yan D. Coupling surface cameras with on-board fluoroscopy: a feasibility study. Med Phys 2011; 38:2937-47. PubMed
  • Aristophanous M, Berbeco RI, Killoran JH, Yap JT, Sher DJ, Allen AM, Larson E, Chen AB. Clinical Utility of 4D FDG-PET/CT Scans in Radiation Treatment Planning. Int J Radiat Oncol Biol Phys 2011. PubMed
  • Killoran JH, Gerbaudo VH, Mamede M, Ionascu D, Park SJ, Berbeco R. Motion artifacts occurring at the lung/diaphragm interface using 4D CT attenuation correction of 4D PET scans. J Appl Clin Med Phys 2011; 12:3502. PubMed
  • Court L, Wagar M, Bogdanov M, Ionascu D, Schofield D, Allen A, Berbeco R, Lingos T. Use of reduced dose rate when treating moving tumors using dynamic IMRT. J Appl Clin Med Phys 2011; 12:3276. PubMed
  • Berbeco RI, Ngwa W, Makrigiorgos GM. Localized Dose Enhancement to Tumor Blood Vessel Endothelial Cells via Megavoltage X-rays and Targeted Gold Nanoparticles: New Potential for External Beam Radiotherapy. Int J Radiat Oncol Biol Phys 2010. PubMed
  • Ngwa W, Makrigiorgos GM, Berbeco RI. Applying gold nanoparticles as tumor-vascular disrupting agents during brachytherapy: estimation of endothelial dose enhancement. Phys Med Biol 2010; 55:6533-48. PubMed
  • Court LE, Seco J, Lu XQ, Ebe K, Mayo C, Ionascu D, Winey B, Giakoumakis N, Aristophanous M, Berbeco R, Rottman J, Bogdanov M, Schofield D, Lingos T. Use of a realistic breathing lung phantom to evaluate dose delivery errors. Med Phys 2010; 37:5850-7. PubMed
  • Aristophanous M, Yap JT, Killoran JH, Chen AB, Berbeco RI. Four-Dimensional Positron Emission Tomography: Implications for Dose Painting of High-Uptake Regions. Int J Radiat Oncol Biol Phys 2010. PubMed
  • Aristophanous M, Rottmann J, Park SJ, Nishioka S, Shirato H, Berbeco RI. Image-guided adaptive gating of lung cancer radiotherapy: a computer simulation study. Phys Med Biol 2010; 55:4321-33. PubMed
  • Court L, Wagar M, Berbeco R, Reisner A, Winey B, Schofield D, Ionascu D, Allen AM, Popple R, Lingos T. Evaluation of the interplay effect when using RapidArc to treat targets moving in the craniocaudal or right-left direction. Med Phys 2010; 37:4-11. PubMed
  • Berbeco RI, Nishioka S, Shirato H. Evaluation of the need for simultaneous orthogonal gated setup imaging. J Appl Clin Med Phys 2010; 11:3203. PubMed
  • Park SJ, Ionascu D, Hacker F, Mamon H, Berbeco R. Automatic marker detection and 3D position reconstruction using cine EPID images for SBRT verification. Med Phys 2009; 36:4536-46. PubMed
  • Wu H, Zhao Q, Berbeco RI, Nishioka S, Shirato H, Jiang SB. Gating based on internal/external signals with dynamic correlation updates. Phys Med Biol 2008; 53:7137-50. PubMed
  • McMahon R, Berbeco R, Nishioka S, Ishikawa M, Papiez L. A real-time dynamic-MLC control algorithm for delivering IMRT to targets undergoing 2D rigid motion in the beam's eye view. Med Phys 2008; 35:3875-88. PubMed
  • Park SJ, Ionascu D, Killoran J, Mamede M, Gerbaudo VH, Chin L, Berbeco R. Evaluation of the combined effects of target size, respiratory motion and background activity on 3D and 4D PET/CT images. Phys Med Biol 2008; 53:3661-79. PubMed
  • Berbeco RI, Hacker F, Zatwarnicki C, Park SJ, Ionascu D, O'Farrell D, Mamon HJ. A novel method for estimating SBRT delivered dose with beam's-eye-view images. Med Phys 2008; 35:3225-31. PubMed
  • Ruan D, Fessler JA, Balter JM, Berbeco RI, Nishioka S, Shirato H. Inference of hysteretic respiratory tumor motion from external surrogates: a state augmentation approach. Phys Med Biol 2008; 53:2923-2936. PubMed
  • Court LE, Wagar M, Ionascu D, Berbeco R, Chin L. Management of the interplay effect when using dynamic MLC sequences to treat moving targets. Med Phys 2008; 35:1926-31. PubMed
  • Li J, Wang L, Mamon H, Kulke MH, Berbeco R, Makrigiorgos GM. Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing. Nat Med 2008; 14:579-84. PubMed
  • Ren Q, Nishioka S, Shirato H, Berbeco RI. Adaptive prediction of respiratory motion for motion compensation radiotherapy. Phys Med Biol 2007; 52:6651-61. PubMed
  • Ionascu D, Jiang SB, Nishioka S, Shirato H, Berbeco RI. Internal-external correlation investigations of respiratory induced motion of lung tumors. Med Phys 2007; 34:3893-903. PubMed
  • Kanoulas E, Aslam JA, Sharp GC, Berbeco RI, Nishioka S, Shirato H, Jiang SB. Derivation of the tumor position from external respiratory surrogates with periodical updating of the internal/external correlation. Phys Med Biol 2007; 52:5443-56. PubMed
  • Berbeco RI, Hacker F, Ionascu D, Mamon HJ. Clinical feasibility of using an EPID in CINE mode for image-guided verification of stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys 2007; 69:258-66. PubMed
  • Seppenwoolde Y, Berbeco RI, Nishioka S, Shirato H, Heijmen B. Accuracy of tumor motion compensation algorithm from a robotic respiratory tracking system: a simulation study. Med Phys 2007; 34:2774-84. PubMed
  • Li J, Berbeco R, Distel RJ, J. s-RT-MELT for rapid mutation scanning using enzymatic selection and real time DNA-melting: new potential for multiplex genetic analysis. Nucleic Acids Res 2007; 35:e84. PubMed
  • Berbeco RI, Nishioka S, Shirato H, Jiang SB. Residual motion of lung tumors in end-of-inhale respiratory gated radiotherapy based on external surrogates. Med Phys 2006; 33:4149-56. PubMed
  • Berbeco RI, Pope CJ, Jiang SB. Measurement of the interplay effect in lung IMRT treatment using EDR2 films. J Appl Clin Med Phys 2007; 7:33-42. PubMed
  • Jiang SB, Sharp GC, Neicu T, Berbeco RI, Flampouri S, Bortfeld T. On dose distribution comparison. Phys Med Biol 2006; 51:759-76. PubMed
  • Neicu T, Berbeco R, Wolfgang J, Jiang SB. Synchronized moving aperture radiation therapy (SMART): improvement of breathing pattern reproducibility using respiratory coaching. Phys Med Biol 2006; 51:617-36. PubMed
  • Berbeco RI, Mostafavi H, Sharp GC, Jiang SB. Towards fluoroscopic respiratory gating for lung tumours without radiopaque markers. Phys Med Biol 2005; 50:4481-90. PubMed
  • Berbeco RI, Nishioka S, Shirato H, Chen GT, Jiang SB. Residual motion of lung tumours in gated radiotherapy with external respiratory surrogates. Phys Med Biol 2005; 50:3655-67. PubMed
  • Berbeco RI, Neicu T, Rietzel E, Chen GT, Jiang SB. A technique for respiratory-gated radiotherapy treatment verification with an EPID in cine mode. Phys Med Biol 2005; 50:3669-79. PubMed
  • Berbeco RI, Jiang SB, Sharp GC, Chen GT, Mostafavi H, Shirato H. Integrated radiotherapy imaging system (IRIS): design considerations of tumour tracking with linac gantry-mounted diagnostic x-ray systems with flat-panel detectors. Phys Med Biol 2004; 49:243-55. PubMed
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