Photo of Stanley W. Ashley,  MD

Stanley W. Ashley, MD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 732-6730
Fax: (617) 264-3688


sashley@partners.org

Stanley W. Ashley, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Frank Sawyer Professor of Surgery, Surgery, Harvard Medical School
  • CMO and Senior VP for Medical Affairs, Administration, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

My research focuses on adaptation of the gastrointestinal epithelium, particulary after resection. We are examining the physiological regulation of the intestinal sodium transporter SGLT1 in health and disease as a novel adjunct to current therapeutic strategies. In addition, I am involved in a variety of clinical studies involving GI tumors.

Publications

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  • Xourafas D, Tavakkoli A, Clancy TE, Ashley SW. Distal pancreatic resection for neuroendocrine tumors: is laparoscopic really better than open? J Gastrointest Surg 2015. PubMed
  • Xourafas D, Tavakkoli A, Clancy TE, Ashley SW. Noninvasive intraductal papillary mucinous neoplasms and mucinous cystic neoplasms: recurrence rates and postoperative imaging follow-up. Surgery 2015; 157:473-83. PubMed
  • Waseem T, Duxbury M, Ashley SW, Robinson MK. Ghrelin promotes intestinal epithelial cell proliferation through PI3K/Akt pathway and EGFR trans-activation both converging to ERK 1/2 phosphorylation. Peptides 2014; 52:113-21. PubMed
  • Kelz RR, Reinke CE, Cofer JB, Ashley SW, Hebert JC, Ko CY. APDS panel session IV: intersection of surgical outcomes and medical education. J Surg Educ 2012; 69:687-92. PubMed
  • Balakrishnan A, Stearns AT, Ashley SW, Tavakkolizadeh A, Rhoads DB. Restricted Feeding Phase Shifts Clock Gene and Sodium Glucose Cotransporter 1 (SGLT1) Expression in Rats. J Nutr 2010; 140:908-14. PubMed
  • Viswanathan SR, Khalpey Z, Ashley SW. Gallbladder lymphoma. Med Oncol 2010. PubMed
  • Ahmadiyeh N, Cho NL, Kellogg KC, Lipsitz SR, Moore FD, Ashley SW, Zinner MJ, Breen EM. Career satisfaction of women in surgery: perceptions, factors, and strategies. J Am Coll Surg 2010; 210:23-8. PubMed
  • Greenberg CC, Ashley SW, Schrag D. Centralization of cancer surgery: what does it mean for surgical training? J Clin Oncol 2009; 27:4637-9. PubMed
  • Abolmaali K, Balakrishnan A, Stearns AT, Rounds J, Rhoads DB, Ashley SW, Tavakkolizadeh A. Circadian variation in intestinal dihydropyrimidine dehydrogenase (DPD) expression: a potential mechanism for benefits of 5FU chrono-chemotherapy. Surgery 2009; 146:269-73. PubMed
  • Mortele KJ,Girshman J,Szejnfeld D,Ashley SW,Erturk SM,Banks PA,Silverman SG. CT-guided percutaneous catheter drainage of acute necrotizing pancreatitis: clinical experience and observations in patients with sterile and infected necrosis. AJR Am J Roentgenol 2008; 192:110-6. PubMed
  • Irani JL,Ashley SW,Brooks DC,Osteen RT,Raut CP,Russell S,Swanson RS,Whang EE,Zinner MJ,Clancy TE. Distal pancreatectomy is not associated with increased perioperative morbidity when performed as part of a multivisceral resection. J Gastrointest Surg 2008; 12:2177-82. PubMed
  • Irani JL,Cutler CS,Whang EE,Clancy TE,Russell S,Swanson RS,Ashley SW,Zinner MJ,Raut CP. Severe acute gastrointestinal graft-vs-host disease: an emerging surgical dilemma in contemporary cancer care. Arch Surg 2008; 143:1041-5; discussion 1046. PubMed
  • Raut CP, Ashley SW. How I Do It: Surgical Management of Gastrointestinal Stromal Tumors. J Gastrointest Surg 2008; 12:1592-9. PubMed
  • Tatli S,Cizginer S,Wieczorek TJ,Ashley SW,Silverman SG. Solitary littoral cell angioma of the spleen: computed tomography and magnetic resonance imaging features. J Comput Assist Tomogr 2008; 32:772-5. PubMed
  • Balakrishnan A,Stearns AT,Rhoads DB,Ashley SW,Tavakkolizadeh A. Defining the transcriptional regulation of the intestinal sodium-glucose cotransporter using RNA-interference mediated gene silencing. Surgery 2008; 144:168-73. PubMed
  • Rocha FG, Sundback CA, Krebs NJ, Leach JK, Mooney DJ, Ashley SW, Vacanti JP, Whang EE. The effect of sustained delivery of vascular endothelial growth factor on angiogenesis in tissue-engineered intestine. Biomaterials 2008; 29:2884-90. PubMed
  • Stearns AT, Balakrishnan A, Rounds JD, Rhoads DB, Ashley SW, Tavakkolizadeh A. Capsaicin-sensitive vagal afferents modulate post-transcriptional regulation of the rat Na+/glucose cotransporter SGLT1. Am J Physiol Gastrointest Liver Physiol 2008; 294:G1078-83. PubMed
  • Behrns KE, Ashley SW, Hunter JG, Carr-Locke D. Early ERCP for gallstone pancreatitis: for whom and when? J Gastrointest Surg 2007; 12:629-33. PubMed
  • Waseem T, Duxbury M, Ito H, Ashley SW, Robinson MK. Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways. Surgery 2008; 143:334-42. PubMed
  • Dellinger EP, Tellado JM, Soto NE, Ashley SW, Barie PS, Dugernier T, Imrie CW, Johnson CD, Knaebel HP, Laterre PF, Maravi-Poma E, Olsina Kissler JJ, Garcia MS, Utzolino S,. Re: Early Antibiotic Treatment for Severe Acute Necrotizing Pancreatitis. Ann Surg 2008; 247:394-395. PubMed
  • Wallace CA, Petrov MS, Soybel DI, Ferzoco SJ, Ashley SW, Tavakkolizadeh A. Influence of Imaging on the Negative Appendectomy Rate in Pregnancy. J Gastrointest Surg 2007; 12:46-50. PubMed
  • Hernandez A, Petrov MS, Brooks DC, Banks PA, Ashley SW, Tavakkolizadeh A. Acute pancreatitis and pregnancy: a 10-year single center experience. J Gastrointest Surg 2007; 11:1623-7. PubMed
  • Javid SH, Ashley S, Breen E. A colorectal curriculum for general surgery residents: are we ready for needs assessment? J Surg Educ 2007; 64:324-7. PubMed
  • Greenberg JA, Irani JL, Greenberg CC, Blanco MA, Lipsitz S, Ashley SW, Breen EM, Hafler JP. The ACGME competencies in the operating room. Surgery 2007; 142:180-4. PubMed
  • Liu JJ, Glickman JN, Li X, Maurer R, Ashley SW, Brooks DC, Carr-Locke DL, Saltzman JR. Smooth muscle remodeling of the gastroesophageal junction after endoluminal gastroplication. Gastrointest Endosc 2007; 65:1023-7. PubMed
  • Raut CP, Morgan JA, Ashley SW. Current issues in gastrointestinal stromal tumors: incidence, molecular biology, and contemporary treatment of localized and advanced disease. Curr Opin Gastroenterol 2007; 23:149-58. PubMed
  • Berzin TM, Rocha FG, Whang EE, Mortele KJ, Ashley SW, Banks PA. Prevalence of primary fungal infections in necrotizing pancreatitis. Pancreatology 2007; 7:63-6. PubMed
  • Liau SS, Ashley SW, Whang EE. Lentivirus-mediated RNA interference of HMGA1 promotes chemosensitivity to gemcitabine in pancreatic adenocarcinoma. J Gastrointest Surg 2006; 10:1254-62; discussion 1263. PubMed
  • Raut CP, Kulke MH, Glickman JN, Swanson RS, Ashley SW. Carcinoid tumors. Curr Probl Surg 2006; 43:383-450. PubMed
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