Photo of Zoltan Arany,  MD, PhD

Zoltan Arany, MD, PhD

Beth Israel Deaconess Medical Center

Beth Israel Deaconess Medical Center
Phone: (617) 735-4252
Fax: (617) 735-4256


zarany@bidmc.harvard.edu

Zoltan Arany, MD, PhD

Beth Israel Deaconess Medical Center

EDUCATIONAL TITLES

  • Lecturer, Medicine, Harvard Medical School
  • Principal Investigator, Medicine, Beth Israel Deaconess Medical Center

Publications

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  • Thom R, Rowe GC, Jang C, Safdar A, Arany Z. Hypoxic Induction of Vascular Endothelial Growth Factor (VEGF) and Angiogenesis in Muscle by Truncated Peroxisome Proliferator-activated Receptor 粒 Coactivator (PGC)-1留. J Biol Chem 2014; 289:8810-7. PubMed
  • Rowe GC, Arany Z. Genetic models of PGC-1 and glucose metabolism and homeostasis. Rev Endocr Metab Disord 2014; 15:21-9. PubMed
  • Icli B, Wara AK, Moslehi J, Sun X, Plovie E, Cahill M, Marchini JF, Schissler A, Padera RF, Shi J, Cheng HW, Raghuram S, Arany Z, Liao R, Croce K, MacRae C, Feinberg MW. MicroRNA-26a regulates pathological and physiological angiogenesis by targeting BMP/SMAD1 signaling. Circ Res 2013; 113:1231-41. PubMed
  • Haq R, Shoag J, Andreu-Perez P, Yokoyama S, Edelman H, Rowe GC, Frederick DT, Hurley AD, Nellore A, Kung AL, Wargo JA, Song JS, Fisher DE, Arany Z, Widlund HR. Oncogenic BRAF regulates oxidative metabolism via PGC1留 and MITF. Cancer Cell 2013; 23:302-15. PubMed
  • Shoag J, Haq R, Zhang M, Liu L, Rowe GC, Jiang A, Koulisis N, Farrel C, Amos CI, Wei Q, Lee JE, Zhang J, Kupper TS, Qureshi AA, Cui R, Han J, Fisher DE, Arany Z. PGC-1 coactivators regulate MITF and the tanning response. Mol Cell 2013; 49:145-57. PubMed
  • Saint-Geniez M, Jiang A, Abend S, Liu L, Sweigard H, Connor KM, Arany Z. PGC-1留 Regulates Normal and Pathological Angiogenesis in the Retina. Am J Pathol 2012. PubMed
  • Rowe GC, Jang C, Patten IS, Arany Z. PGC-1{beta}{beta} REGULATES ANGIOGENESIS IN SKELETAL MUSCLE. Am J Physiol Endocrinol Metab 2011. PubMed
  • LeBrasseur NK, Walsh K, Arany Z. Metabolic benefits of resistance training and fast glycolytic skeletal muscle. Am J Physiol Endocrinol Metab 2010; 300:E3-10. PubMed
  • Shoag J, Arany Z. Regulation of Hypoxia-Inducible Genes by PGC-1{alpha} Arterioscler Thromb Vasc Biol 2010; 30:662-6. PubMed
  • Gupta RK, Arany Z, Seale P, Mepani RJ, Ye L, Conroe HM, Roby YA, Kulaga H, Reed RR, Spiegelman BM. Transcriptional control of preadipocyte determination by Zfp423. Nature 2010; 464:619-23. PubMed
  • Chinsomboon J, Ruas J, Gupta RK, Thom R, Shoag J, Rowe GC, Sawada N, Raghuram S, Arany Z. The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle. Proc Natl Acad Sci U S A 2009; 106:21401-6. PubMed
  • Arany Z. PGC-1 coactivators and skeletal muscle adaptations in health and disease. Curr Opin Genet Dev 2008; 18:426-34. PubMed
  • Arany Z, Wagner BK, Ma Y, Chinsomboon J, Laznik D, Spiegelman BM. Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1alpha and oxidative phosphorylation. Proc Natl Acad Sci U S A 2008; 105:4721-6. PubMed
  • Arany Z, Foo SY, Ma Y, Ruas JL, Bommi-Reddy A, Girnun G, Cooper M, Laznik D, Chinsomboon J, Rangwala SM, Baek KH, Rosenzweig A, Spiegelman BM. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature 2008; 451:1008-12. PubMed
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