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External Cancer Publications

Latest in Cancer Research Publications

Oncogene

Oncogene is one of the world’s leading cancer journals. It is published weekly and covers all aspects of the structure and function of Oncogenes. Oncogene also publishes 8 Reviews issues a year, on a broad range of topics.
Oncogene
Thyroid hormone receptor mutants implicated in human hepatocellular carcinoma display an altered target gene repertoire
LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer
Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation
Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene
The Cdk inhibitor p57Kip2 controls LIM-kinase 1 activity and regulates actin cytoskeleton dynamics
Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation
A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer
A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis
RNA aptamers interfering with nucleophosmin oligomerization induce apoptosis of cancer cells
PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis
Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines
Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration
Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type- and mutation-specific manner
Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions
Pro-proliferative FoxM1 is a target of p53-mediated repression
Pannexin2 as a novel growth regulator in C6 glioma cells
‘Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma’
SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue
Genetic inactivation of ApoJ/clusterin: effects on prostate tumourigenesis and metastatic spread
Lysine 269 is essential for cyclin D1 ubiquitylation by the SCFFbx4/αB-crystallin ligase and subsequent proteasome-dependent degradation
Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells
TLR4 signaling induced by lipopolysaccharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer
Transcription activity is required for p53-dependent tumor suppression
Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells
YKL-40, a secreted glycoprotein, promotes tumor angiogenesis
A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways
The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts
Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer
The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer
Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer
PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression
Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage
Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein
Functional variant of KLOTHO: a breast cancer risk modifier among BRCA1 mutation carriers of Ashkenazi origin
Downregulation of E-cadherin is an essential event in activating β-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells
RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1
Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma
Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation
RalA suppresses early stages of Ras-induced squamous cell carcinoma progression
HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions
Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways
Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells
Shc is required for ErbB2-induced inhibition of apoptosis but is dispensable for cell proliferation and disruption of cell polarity
Modeling the effect of the RB tumor suppressor on disease progression: dependence on oncogene network and cellular context
Chemotherapy induces NEDP1-mediated destabilization of MDM2
AKT1 mutations in bladder cancer: identification of a novel oncogenic mutation that can co-operate with E17K
The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival
Selective inhibition of choline kinase simultaneously attenuates MAPK and PI3K/AKT signaling
Cytokine expression and signaling in drug-induced cellular senescence