Photo of Steven L. Chang,  MD

Steven L. Chang, MD

Brigham And Women's Hospital

Brigham And Women's Hospital
Phone: (617) 525-3117
Fax: (617) 566-3475


SLCHANG@partners.org

Steven L. Chang, MD

Brigham And Women's Hospital

EDUCATIONAL TITLES

  • Assistant Professor, Surgery, Harvard Medical School
  • Associate Surgeon, Surgery, Brigham And Women's Hospital

DF/HCC PROGRAM AFFILIATION

Research Abstract

As a fellowship trained Urologic Oncologist, I have expertise in the evaluation and management of patients with urologic malignancies. I also have a Master of Science in Health Services Research, which has allowed me to apply principles of economic evaluation and decision analysis to clinical problems in urology. The overarching goal of the my research is to develop clinical recommendations that will improve the care of patients with urologic malignancies while reducing over the overall burden of these diseases on the United States health care system.

Publications

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  • Hanna N, Sun M, Meyer CP, Nguyen PL, Pal SK, Chang SL, de Velasco G, Trinh QD, Choueiri TK. Survival Analyses of Metastatic Renal Cancer Patients Treated With Targeted Therapy With or Without Cytoreductive Nephrectomy: A National Cancer Data Base Study. J Clin Oncol 2016. PubMed
  • Wang Y, Chen YW, Leow JJ, Levy AC, Chang SL, Gelpi FH. Cost-Effectiveness of Management Options for Small Renal Mass: A Systematic Review. Am J Clin Oncol 2016. PubMed
  • Leow JJ, Heah NH, Chang SL, Chong YL, Png KS. Outcomes After Robotic Versus Laparoscopic Partial Nephrectomy: An Updated Meta-Analysis Of 4919 Patients. J Urol 2016. PubMed
  • Cole AP, Leow JJ, Chang SL, Chung BI, Meyer CP, Kibel AS, Menon M, Nguyen PL, Choueiri TK, Reznor G, Lipsitz SR, Sammon JD, Sun M, Trinh QD. Surgeon and Hospital-Level Variation in the Costs of Robot-Assisted Radical Prostatectomy. J Urol 2016. PubMed
  • Leow JJ, Chang SL, Meyer CP, Wang Y, Hanske J, Sammon JD, Cole AP, Preston MA, Dasgupta P, Menon M, Chung BI, Trinh QD. Robot-assisted Versus Open Radical Prostatectomy: A Contemporary Analysis of an All-payer Discharge Database. Eur Urol 2016. PubMed
  • Leow JJ, Chang SL, Trinh QD. Accurately Determining Patients Who Underwent Robot-Assisted Surgery: Limitations Of Administrative Databases. BJU Int 2016. PubMed
  • Tinay I, Gelpi-Hammerschmidt F, Leow JJ, Allard CB, Rodriguez D, Wang Y, Chung BI, Chang SL. Trends in utilization, perioperative outcomes and costs for nephroureterectomies in the management of upper tract urothelial carcinoma (UTUC): a 10-year population-based analysis. BJU Int 2015. PubMed
  • Allard CB, Gelpi-Hammerschmidt F, Harshman LC, Choueiri TK, Faiena I, Modi P, Chung BI, Tinay I, Singer EA, Chang SL. Contemporary trends in high-dose interleukin-2 use for metastatic renal cell carcinoma in the United States. Urol Oncol 2015. PubMed
  • Gelpi-Hammerschmidt F, Tinay I, Allard CB, Su LM, Preston MA, Trinh QD, Kibel AS, Wang Y, Chung BI, Chang SL. The Contemporary Incidence and Sequelae of Rhabdomyolysis Following Extirpative Renal Surgery: A Population Based Analysis. J Urol 2015. PubMed
  • Kramann R, Fleig SV, Schneider RK, Fabian SL, DiRocco DP, Maarouf O, Wongboonsin J, Ikeda Y, Heckl D, Chang SL, Rennke HG, Waikar SS, Humphreys BD. Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis. J Clin Invest 2015; 125:2935-51. PubMed
  • Chang SL, Kibel AS, Brooks JD, Chung BI. The impact of robotic surgery on the surgical management of prostate cancer in the USA. BJU Int 2015. PubMed
  • Chung BI, Leow JJ, Gelpi-Hammerschmidt F, Wang Y, Del Giudice F, De S, Chou EP, Song KH, Almario L, Chang SL. Racial Disparities in Postoperative Complications After Radical Nephrectomy: A Population-based Analysis. Urology 2015; 85:1411-6. PubMed
  • Allard CB, Meyer CP, Gandaglia G, Chang SL, Chun FK, Gelpi-Hammerschmidt F, Hanske J, Kibel AS, Preston MA, Trinh QD. The Effect of Resident Involvement on Perioperative Outcomes in Transurethral Urologic Surgeries. J Surg Educ 2015. PubMed
  • Leow JJ, Reese S, Trinh QD, Bellmunt J, Chung BI, Kibel AS, Chang SL. Impact of surgeon volume on the morbidity and costs of radical cystectomy in the USA: a contemporary population-based analysis. BJU Int 2015. PubMed
  • Leow JJ, Orsola A, Chang SL, Bellmunt J. A contemporary review of management and prognostic factors of upper tract urothelial carcinoma. Cancer Treat Rev 2015. PubMed
  • Lucca I, Leow JJ, Shariat SF, Chang SL. Diagnosis and management of upper tract urothelial carcinoma. Hematol Oncol Clin North Am 2015; 29:271-88, ix. PubMed
  • Meyer CP, Hanske J, Friedlander DF, Schmid M, Dahlem R, Trinh VQ, Chang SL, Kibel AS, Chun FK, Fisch M, Trinh QD, Eswara JR. The impact of resident involvement in male one-stage anterior urethroplasties. Urology 2015; 85:937-41. PubMed
  • Martin-Doyle W, Leow JJ, Orsola A, Chang SL, Bellmunt J. Improving selection criteria for early cystectomy in high-grade t1 bladder cancer: a meta-analysis of 15,215 patients. J Clin Oncol 2015; 33:643-50. PubMed
  • Leow JJ, Gandaglia G, Sood A, Ruhotina N, Klett DE, Sammon JD, Schmid M, Sun M, Chang SL, Kibel AS, Trinh QD. Readmissions after major urologic cancer surgery. Can J Urol 2014; 21:7537-46. PubMed
  • Schmid M, Ravi P, Abd-El-Barr AE, Klap J, Sammon JD, Chang SL, Menon M, Kibel AS, Fisch M, Trinh QD. Chronic kidney disease and perioperative outcomes in urological oncological surgery. Int J Urol 2014. PubMed
  • Ravi P, Karakiewicz PI, Roghmann F, Gandaglia G, Choueiri TK, Menon M, McKay RR, Nguyen PL, Sammon JD, Sukumar S, Varda B, Chang SL, Kibel AS, Sun M, Trinh QD. Mental health outcomes in elderly men with prostate cancer. Urol Oncol 2014. PubMed
  • Schmid M, Abd-El-Barr AE, Gandaglia G, Sood A, Olugbade K, Ruhotina N, Sammon JD, Varda B, Chang SL, Kibel AS, Chun FK, Menon M, Fisch M, Trinh QD. Predictors of 30-day acute kidney injury following radical and partial nephrectomy for renal cell carcinoma. Urol Oncol 2014. PubMed
  • Gandaglia G, Varda B, Sood A, Pucheril D, Konijeti R, Sammon JD, Sukumar S, Menon M, Sun M, Chang SL, Montorsi F, Kibel AS, Trinh QD. Short-term perioperative outcomes of patients treated with radical cystectomy for bladder cancer included in the National Surgical Quality Improvement Program (NSQIP) database. Can Urol Assoc J 2014; 8:E681-7. PubMed
  • Leow JJ, Reese SW, Jiang W, Lipsitz SR, Bellmunt J, Trinh QD, Chung BI, Kibel AS, Chang SL. Propensity-matched comparison of morbidity and costs of open and robot-assisted radical cystectomies: a contemporary population-based analysis in the United States. Eur Urol 2014. PubMed
  • Leow JJ, Martin-Doyle W, Fay AP, Choueiri TK, Chang SL, Bellmunt J. A systematic review and meta-analysis of adjuvant and neoadjuvant chemotherapy for upper tract urothelial carcinoma. Eur Urol 2014. PubMed
  • Ruhotina N, Dagenais J, Gandaglia G, Sood A, Abdollah F, Chang SL, Leow JJ, Olugbade K, Rai A, Sammon JD, Schmid M, Varda B, Zorn KC, Menon M, Kibel AS, Trinh QD. The impact of resident involvement in minimally-invasive urologic oncology procedures. Can Urol Assoc J 2014; 8:334-40. PubMed
  • Shinagare AB, Silverman SG, Gershanik EF, Chang SL, Khorasani R. Evaluating hematuria: impact of guideline adherence on urologic cancer diagnosis. Am J Med 2014. PubMed
  • Bhojani N, Gandaglia G, Sood A, Rai A, Pucheril D, Chang SL, Karakiewicz PI, Menon M, Olugbade K, Ruhotina N, Sammon JD, Sukumar S, Sun M, Ghani KR, Schmid M, Varda B, Kibel AS, Zorn KC, Trinh QD. Morbidity and mortality after benign prostatic hyperplasia surgery: data from the American College of Surgeons national surgical quality improvement program. J Endourol 2014. PubMed
  • Leow JJ, Martin-Doyle W, Rajagopal PS, Patel CG, Anderson EM, Rothman AT, Cote RJ, Urun Y, Chang SL, Choueiri TK, Bellmunt J. Adjuvant chemotherapy for invasive bladder cancer: a 2013 updated systematic review and meta-analysis of randomized trials. Eur Urol 2014. PubMed
  • Antczak C, Trinh VQ, Sood A, Ravi P, Roghmann F, Trudeau V, Chang SL, Karakiewicz PI, Kibel AS, Krishna N, Nguyen PL, Saad F, Sammon JD, Sukumar S, Zorn KC, Sun M, Trinh QD. The health care burden of skeletal related events in patients with renal cell carcinoma and bone metastasis. J Urol 2014. PubMed
  • Gandaglia G, Sammon JD, Chang SL, Choueiri TK, Hu JC, Karakiewicz PI, Kibel AS, Kim SP, Konijeti R, Montorsi F, Nguyen PL, Sukumar S, Menon M, Sun M, Trinh QD. Comparative effectiveness of robot-assisted and open radical prostatectomy in the postdissemination era. J Clin Oncol 2014. PubMed
  • Look Hong NJ, Chang SL, Raut CP. The economic impact of cytoreductive surgery and tyrosine kinase inhibitor therapy in the treatment of advanced gastrointestinal stromal tumours: a Markov chain decision analysis. Eur J Cancer 2014; 50:397-405. PubMed
  • Chang SL, Cipriano LE, Harshman LC, Garber AM, Chung BI. Cost-effectiveness analysis of nephron sparing options for the management of small renal masses. J Urol 2011; 185:1591-7. PubMed
  • Hsu M, Chang SL, Ferrari M, Nolley R, Presti JC, Brooks JD. Length of site-specific positive surgical margins as a risk factor for biochemical recurrence following radical prostatectomy. Int J Urol 2014. PubMed
  • Chang SL, Harshman LC, Presti JC. Impact of common medications on serum total prostate-specific antigen levels: analysis of the National Health and Nutrition Examination Survey. J Clin Oncol 2010; 28:3951-7. PubMed
  • Levesque BG, Cipriano LE, Chang SL, Lee KK, Owens DK, Garber AM. Cost effectiveness of alternative imaging strategies for the diagnosis of small-bowel Crohn's disease. Clin Gastroenterol Hepatol 2010; 8:261-7, 267.e1-4. PubMed
  • Chang SL, Gonzalgo ML. Editorial comment. J Urol 2010; 183:459; discussion 459. PubMed
  • Chang SL, Freedland SJ, Terris MK, Aronson WJ, Kane CJ, Amling CL, Presti JC. Freedom from a detectable ultrasensitive prostate-specific antigen at two years after radical prostatectomy predicts a favorable clinical outcome: analysis of the SEARCH database. Urology 2010; 75:439-44. PubMed
  • Chang SL, Liao JC, Shinghal R. Decreasing use of luteinizing hormone-releasing hormone agonists in the United States is Independent of Reimbursement Changes: A Medicare and Veterans Health Administration claims analysis. J Urol 2009; 182:255-60; discussion 261. PubMed
  • Chang SL, Gonzalgo ML. Surgery: laparoscopic prostatectomy: learning curve and cancer control. Nat Rev Urol 2009; 6:361-2. PubMed
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