DF/HCC Program Affiliation

Leader, Cancer Survivorship Program
Member, Cancer Genetics Program
Member, Cancer Risk Reduction Program
Member, Outcomes Research Program

DF/HCC Associations

Member, Center Scientific Council

Research Abstract

My research focuses on secondary cancer prevention and detection in childhood cancer survivors. Ongoing studies include assessment of genetic risk factors for primary and secondary cancers, evaluation of breast cancer screening after chest irradiation during childhood and studies of the role of genetic counseling and genetic testing in promoting quality-of-life of survivors. In addition, we are interested in the long-term effects of cancer treatment on adolescent and young adult survivors, specifically assessing medical and psychological outcomes such as hearing, fertility and cardiac function after chemotherapy exposure and cognitive function after brain irradiation.

Publications

• George RE, Attiyeh EF, Li S, Moreau LA, Neuberg D, Li C, Fox EA, Meyerson M, Diller L, Fortina P, Look AT, Maris JM. Genome-Wide Analysis of Neuroblastomas using High-Density Single Nucleotide Polymorphism Arrays. PLoS ONE 2007; 2:e255
  PMID: 17327916
• Henderson TO, Whitton J, Stovall M, Mertens AC, Mitby P, Friedman D, Strong LC, Hammond S, Neglia JP, Meadows AT, Robison L, Diller L. Secondary sarcomas in childhood cancer survivors: a report from the Childhood Cancer Survivor Study. Journal of the National Cancer Institute 2007 Feb 21; 99(4):300-8
  PMID: 17312307
• Radulescu VC, Gerrard M, Moertel C, Grundy PE, Mathias L, Feusner J, Diller L, Dome JS. Treatment of recurrent clear cell sarcoma of the kidney with brain metastasis. Pediatr Blood Cancer 2007 Jan 16;
  PMID: 17226850
• Duffey-Lind EC, O'Holleran E, Healey M, Vettese M, Diller L, Park ER. Transitioning to survivorship: a pilot study. J Pediatr Oncol Nurs 2006 Nov-Dec; 23(6):335-43
  PMID: 17035624
• Moreau LA, McGrady P, London WB, Shimada H, Cohn SL, Maris JM, Diller L, Look AT, George RE. Does MYCN amplification manifested as homogeneously staining regions at diagnosis predict a worse outcome in children with neuroblastoma? A Children's Oncology Group study. Clin Cancer Res 2006 Oct 1; 12(19):5693-7
  PMID: 17020972
• Recklitis CJ, Lockwood RA, Rothwell MA, Diller LR. Suicidal ideation and attempts in adult survivors of childhood cancer. J Clin Oncol 2006 Aug 20; 24(24):3852-7
  PMID: 16921037
• Guinan EC, Kalish LA, Berry WS, McDaniel S, Lehmann LE, Diller LR. A novel pattern of transaminase elevation associated with autologous transplant for neuroblastoma. Pediatr Transplant 2006 Sep; 10(6):669-76
  PMID: 16911489
• George RE, Li S, Medeiros-Nancarrow C, Neuberg D, Marcus K, Shamberger RC, Pulsipher M, Grupp SA, Diller L. High-risk neuroblastoma treated with tandem autologous peripheral-blood stem cell-supported transplantation: long-term survival update. J Clin Oncol 2006 Jun 20; 24(18):2891-6
  PMID: 16782928
• Ng AK, Li S, Recklitis C, Neuberg D, Chakrabarti S, Silver B, Diller L. A comparison between long-term survivors of Hodgkin's disease and their siblings on fatigue level and factors predicting for increased fatigue. Ann Oncol 2005 Dec; 16(12):1949-55
  PMID: 16227316
• Nichols KE, Levitz S, Shannon KE, Wahrer DC, Bell DW, Chang G, Hegde S, Neuberg D, Shafman T, Tarbell NJ, Mauch P, Ishioka C, Haber DA, Diller L. Heterozygous germline ATM mutations do not contribute to radiation-associated malignancies after Hodgkin's disease. J Clin Oncol 1999 Apr; 17(4):1259
  PMID: 10561187
• Diller L, Ghahremani M, Morgan J, Grundy P, Reeves C, Breslow N, Green D, Neuberg D, Pelletier J, Li FP. Constitutional WT1 mutations in Wilms' tumor patients. J Clin Oncol 1998 Nov; 16(11):3634-40
  PMID: 9817285