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Paul Goss FRCP M.B. BCh Ph.D.

Professor, Department of Medicine, Harvard Medical School

Director, Breast Cancer Research, MGH Cancer Center, Massachusetts General Hospital

Contact Info

Paul Goss
Massachusetts General Hospital
55 Fruit Street
Boston, MA, 02114
Mailstop: Lawrence House 302
Phone: 6177243118
Fax: 6176430589
No email address available.

Assistant

Katie Roche
Phone: 6176432208
Fax: 6176430589
kroche1@partners.org

DF/HCC Program Affiliation

Co-Leader, Breast Cancer Program

DF/HCC Associations

Member, Center Scientific Council

Publications

  • Pater J, Tu D, Shepherd L, Ingle JN, Goss PE. Decision making in adjuvant trials in breast cancer: the NCIC CTG MA.17 trial as an example. Breast Cancer Res Treat 2007 May 3;
    PMID: 17476587
  • Goss PE, Ingle JN, Martino S, Robert NJ, Muss HB, Piccart MJ, Castiglione M, Tu D, Shepherd LE, Pritchard KI, Livingston RB, Davidson NE, Norton L, Perez EA, Abrams JS, Cameron DA, Palmer MJ, Pater JL,. Efficacy of letrozole extended adjuvant therapy according to estrogen receptor and progesterone receptor status of the primary tumor: National Cancer Institute of Canada Clinical Trials Group MA.17. J Clin Oncol 2007 May 20; 25(15):2006-11
    PMID: 17452676
  • Moy B, Goss PE. TEACH: Tykerb evaluation after chemotherapy. Clin Breast Cancer 2007 Feb; 7(6):489-92
    PMID: 17386127
  • Booth CM, Pater JL, Goss PE. Identifying breast cancer patients most likely to benefit from aromatase inhibitor therapy after adjuvant tamoxifen. Cancer 2007 May 1; 109(9):1927-8; author reply 1928
    PMID: 17354227
  • Goss PE, Strasser-Weippl K, Qi S, Hu H. Effects of liarozole fumarate (R85246) in combination with tamoxifen on N-methyl-N-nitrosourea (MNU)-induced mammary carcinoma and uterus in the rat model. BMC Cancer 2007; 7:26
    PMID: 17266767
  • Vachon CM, Ingle JN, Suman VJ, Scott CG, Gottardt H, Olson JE, Goss PE. Pilot study of the impact of letrozole vs. placebo on breast density in women completing 5 years of tamoxifen. Breast 2007 Apr; 16(2):204-10
    PMID: 17145182
  • Chien AJ, Goss PE. Aromatase inhibitors and bone health in women with breast cancer. J Clin Oncol 2006 Nov 20; 24(33):5305-12
    PMID: 17114665
  • Moy B, Goss PE. Lapatinib: current status and future directions in breast cancer. Oncologist 2006 Nov-Dec; 11(10):1047-57
    PMID: 17110623
  • Goss PE, Qi S, Hu H, Cheung AM. The effects of atamestane and toremifene alone and in combination compared with letrozole on bone, serum lipids and the uterus in an ovariectomized rat model. Breast Cancer Res Treat 2006 Oct 25;
    PMID: 17063268
  • Moy B, Tu D, Pater JL, Ingle JN, Shepherd LE, Whelan TJ, Goss PE. Clinical outcomes of ethnic minority women in MA.17: a trial of letrozole after 5 years of tamoxifen in postmenopausal women with early stage breast cancer. Ann Oncol 2006 Nov; 17(11):1637-43
    PMID: 16936184
  • Moy B, Goss PE. Estrogen receptor pathway: resistance to endocrine therapy and new therapeutic approaches. Clin Cancer Res 2006 Aug 15; 12(16):4790-3
    PMID: 16914563
  • Ryan PD, Goss PE. Adjuvant hormonal therapy in peri- and postmenopausal breast cancer. Oncologist 2006 Jul; 11(7):718-31
    PMID: 16880231
  • Delea TE, Karnon J, Goss PE. Conclusions regarding relative cost-utility of alternative strategies for use of aromatase inhibitors in postmenopausal women with early breast cancer are premature. Ann Oncol 2006 Jul 27;
    PMID: 16873429
  • Perez EA, Josse RG, Pritchard KI, Ingle JN, Martino S, Findlay BP, Shenkier TN, Tozer RG, Palmer MJ, Shepherd LE, Liu S, Tu D, Goss PE. Effect of letrozole versus placebo on bone mineral density in women with primary breast cancer completing 5 or more years of adjuvant tamoxifen: a companion study to NCIC CTG MA.17. J Clin Oncol 2006 Aug 1; 24(22):3629-35
    PMID: 16822845
  • Goss PE. Preventing relapse beyond 5 years: the MA.17 extended adjuvant trial. Semin Oncol 2006 Apr; 33(2 Suppl 7):S8-12
    PMID: 16730271
  • Cigler T, Goss PE. Aromatase inhibitor withdrawal response in metastatic breast cancer. J Clin Oncol 2006 Apr 20; 24(12):1955-6
    PMID: 16622274
  • Ingle JN, Tu D, Pater JL, Martino S, Robert NJ, Muss HB, Piccart MJ, Castiglione M, Shepherd LE, Pritchard KI, Livingston RB, Davidson NE, Norton L, Perez EA, Abrams JS, Cameron DA, Palmer MJ, Goss PE. Duration of letrozole treatment and outcomes in the placebo-controlled NCIC CTG MA.17 extended adjuvant therapy trial. Breast Cancer Res Treat 2006 Mar 16;
    PMID: 16541302
  • Karnon J, Delea T, Johnston SR, Smith R, Brandman J, Sung J, Goss PE. Cost effectiveness of extended adjuvant letrozole in postmenopausal women after adjuvant tamoxifen therapy: the UK perspective. Pharmacoeconomics 2006; 24(3):237-50
    PMID: 16519546
  • Goss PE, Qi S, Cheung AM, Hu H, Mendes M, Pritzker KP. The selective estrogen receptor modulator SCH 57068 prevents bone loss, reduces serum cholesterol and blocks estrogen-induced uterine hypertrophy in ovariectomized rats. J Steroid Biochem Mol Biol 2004 Sep; 92(1-2):79-87
    PMID: 15544933
  • Goss PE, Qi S, Josse RG, Pritzker KP, Mendes M, Hu H, Waldman SD, Grynpas MD. The steroidal aromatase inhibitor exemestane prevents bone loss in ovariectomized rats. Bone 2004 Mar; 34(3):384-92
    PMID: 15003786
  • Goss PE, Ingle JN, Martino S, Robert NJ, Muss HB, Piccart MJ, Castiglione M, Tu D, Shepherd LE, Pritchard KI, Livingston RB, Davidson NE, Norton L, Perez EA, Abrams JS, Therasse P, Palmer MJ, Pater JL. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N Engl J Med 2003 Nov 6; 349(19):1793-802
    PMID: 14551341