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Jason L. Hornick, MD, PhD

Associate Professor, Department of Pathology, Harvard Medical School

Director, Immunohistochemistry Laboratory, Department of Pathology, Brigham & Women's Hospital

Director of Surgical Pathology, Department of Pathology, Brigham & Women's Hospital

Consultant, Department of Pathology, Dana-Farber Cancer Institute

Contact Info

Jason Hornick
Brigham and Women's Hospital
Department of Pathology

Boston, MA, 02115
Phone not available.
Email not available


Not Available.

DF/HCC Program Affiliation

Gastrointestinal Malignancies

Research Abstract

My major research interests are soft tissue sarcomas, gastrointestinal stromal tumor (GIST), gastrointestinal cancers, and mastocytosis. My focus in soft tissue sarcomas includes evaluating histologic and immunohistochemical parameters that predict clinical outcome, and identifying diagnostic and predictive biomarkers. I study "wild-type" GISTs, focusing on the pathogenesis and clinical significance of succinate dehydrogenase-deficient GIST. I also investigate succinate dehydrogenase deficiency in paraganglioma and renal cell carcinoma. I am interested in extramedullary mastocytosis, especially involvement of the gastrointestinal tract. I also study biomarkers in lung cancer, colon cancer, and neuroendocrine tumors.


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