DF/HCC Program Affiliation

Translational Pharmacology and Early Therapeutic Trials, Co-Leader
Lymphoma and Myeloma
Gastrointestinal Malignancies
Neuro-Oncology

DF/HCC Associations

Associate Director, Clinical Science, Executive Committee
Chair, Clinical Science Coordinating Committee
Member, Center Scientific Council
Scientific Advisor, Cancer Pharmacology

Research Abstract

Major interest is in the clinical testing, pharmaco-kinetics, and biochemical pharacology of new anticancer drugs, particulary natural products and signal transdution inhibitors.

Publications

• Wilson WH, Bates SE, Fojo A, Bryant G, Zhan Z, Regis J, Wittes RE, Jaffe ES, Steinberg SM, Herdt J.Controlled trial of dexverapamil, a modulator of multidrug resistance, in lymphomas refractory to EPOCH chemotherapy.J Clin Oncol 1995 Aug;13(8):1995-2004.
  7636540
• Wilson WH, Jamis-Dow C, Bryant G, Balis FM, Klecker RW, Bates SE, Chabner BA, Steinberg SM, Kohler DR, Wittes RE.Phase I and pharmacokinetic study of the multidrug resistance modulator dexverapamil with EPOCH chemotherapy.J Clin Oncol 1995 Aug;13(8):1985-
  7636539
• Saikawa Y, Knight CB, Saikawa T, Page ST, Chabner BA, Elwood PC.Decreased expression of the human folate receptor mediates transport-defective methotrexate resistance in KB cells.J Biol Chem 1993 Mar 5;268(7):5293-301.
  7680349